Search Results - "Lohoff, F.W"
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Case–control association analysis of polymorphisms in the delta-opioid receptor, OPRD1 , with cocaine and opioid addicted populations
Published in Drug and alcohol dependence (01-01-2013)“…Abstract Background Addiction susceptibility and treatment responsiveness are greatly influenced by genetic factors. Sequence variation in genes involved in…”
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VMAT1 deletion causes neuronal loss in the hippocampus and neurocognitive deficits in spatial discrimination
Published in Neuroscience (01-03-2013)“…Highlights ► VMAT1 is expressed in mouse brain. ► Deletion of VMAT1 results in reduced neurogenesis and apoptosis in the hippocampus. ► VMAT2 expression is not…”
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Association between variation in the human KCNJ10 potassium ion channel gene and seizure susceptibility
Published in Epilepsy research (01-02-2004)“…Purpose: Our research program uses genetic linkage and association analysis to identify human seizure sensitivity and resistance alleles. Quantitative trait…”
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Interaction between polymorphisms in serotonin transporter genes predict treatment response to venlafaxine XR in generalized anxiety disorder
Published in The pharmacogenomics journal (01-10-2013)“…Variation in genes involved in serotonergic signaling is thought to be associated with antidepressant treatment response in generalized anxiety disorder (GAD)…”
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Serotonin receptor 2A (HTR2A) gene polymorphism predicts treatment response to venlafaxine XR in generalized anxiety disorder
Published in The pharmacogenomics journal (01-02-2013)“…Generalized anxiety disorder (GAD) is a chronic psychiatric disorder with significant morbidity and mortality. Antidepressant drugs are the preferred choice…”
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Genetic variation in OPRD1 and the response to treatment for opioid dependence with buprenorphine in European-American females
Published in The pharmacogenomics journal (01-06-2014)“…Two commonly prescribed treatments for opioid addiction are methadone and buprenorphine. Although these drugs show some efficacy in treating opioid dependence,…”
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Confirmation of association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene and bipolar I disorder
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (05-11-2005)“…Recent studies have indicated that the brain‐derived neurotrophic factor (BDNF) gene is involved in the etiology of bipolar disorder (BPD). Two family‐based…”
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Exome sequence analysis of Finnish patients with clozapine-induced agranulocytosis
Published in Molecular psychiatry (01-04-2014)Get full text
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Functional genetic variants in the vesicular monoamine transporter 1 modulate emotion processing
Published in Molecular psychiatry (01-01-2014)“…Emotional behavior is in part heritable and often disrupted in psychopathology. Identification of specific genetic variants that drive this heritability may…”
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Supportive evidence for an allelic association of the human KCNJ10 potassium channel gene with idiopathic generalized epilepsy
Published in Epilepsy research (01-02-2005)“…Quantitative trait loci (QTL) mapping in mice revealed a seizure-related QTL ( Szs1), for which the inward-rectifying potassium channel Kcnj10 is the most…”
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