Search Results - "Lohmann, Suzanne M."

Physiology and pathophysiology of vascular signaling controlled by cyclic guanosine 3', 5'-cyclic monophosphate-dependent protein kinase by MÜNZEL, Thomas, FEIL, Robert, MÜLSCH, Alexander, LOHMANN, Suzanne M, HOFMANN, Franz, WALTER, Ulrich

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Inhibition of Calcineurin-NFAT Hypertrophy Signaling by cGMP-Dependent Protein Kinase Type I in Cardiac Myocytes by Fiedler, Beate, Lohmann, Suzanne M., Smolenski, Albert, Linnemüller, Stephan, Pieske, Burkert, Schröder, Frank, Molkentin, Jeffery D., Drexler, Helmut, Wollert, Kai C.

“…Recent investigation has focused on identifying signaling pathways that inhibit cardiac hypertrophy, a major risk factor for cardiovascular morbidity and…”
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cGMP-dependent Protein Kinase Type I Inhibits TAB1-p38 Mitogen-activated Protein Kinase Apoptosis Signaling in Cardiac Myocytes by Fiedler, Beate, Feil, Robert, Hofmann, Franz, Willenbockel, Christian, Drexler, Helmut, Smolenski, Albert, Lohmann, Suzanne M., Wollert, Kai C.

“…Cardiac myocyte apoptosis during ischemia and reperfusion (I/R) is tightly controlled by a complex network of stress-responsive signaling pathways. One…”
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Active Rho Kinase (ROK-α) Associates with Insulin Receptor Substrate-1 and Inhibits Insulin Signaling in Vascular Smooth Muscle Cells by Begum, Najma, Sandu, Oana A., Ito, Masaaki, Lohmann, Suzanne M., Smolenski, Albert

“…Recent studies from our laboratory have shown that insulin stimulates myosin-bound phosphatase (MBP) in vascular smooth muscle cells (VSMCs) by decreasing…”
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cGMP Inhibition of Na+/H+ Antiporter 3 (NHE3) Requires PDZ Domain Adapter NHERF2, a Broad Specificity Protein Kinase G-anchoring Protein by Cha, Boyoung, Kim, Jae Ho, Hut, Hans, Hogema, Boris M., Nadarja, Janani, Zizak, Mirza, Cavet, Megan, Lee-Kwon, Whaseon, Lohmann, Suzanne M., Smolenski, Albert, Tse, Chung Ming, Yun, Chris, de Jonge, Hugo R., Donowitz, Mark

“…Electroneutral NaCl absorption mediated by Na+/H+ exchanger 3 (NHE3) is important in intestinal and renal functions related to water/Na+ homeostasis. cGMP…”
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Gene Transfer of cGMP-Dependent Protein Kinase I Enhances the Antihypertrophic Effects of Nitric Oxide in Cardiomyocytes by Wollert, Kai C, Fiedler, Beate, Gambaryan, Stepan, Smolenski, Albert, Heineke, Jörg, Butt, Elke, Trautwein, Christian, Lohmann, Suzanne M, Drexler, Helmut

“…NO acting through soluble guanylyl cyclase and cGMP formation is a negative regulator of cardiomyocyte hypertrophy. Downstream targets mediating the inhibitory…”
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Thrombin and Collagen Induce a Feedback Inhibitory Signaling Pathway in Platelets Involving Dissociation of the Catalytic Subunit of Protein Kinase A from an NFκB-IκB Complex by Gambaryan, Stepan, Kobsar, Anna, Rukoyatkina, Natalia, Herterich, Sabine, Geiger, Joerg, Smolenski, Albert, Lohmann, Suzanne M., Walter, Ulrich

“…Protein kinase A (PKA) activation by cAMP phosphorylates multiple target proteins in numerous platelet inhibitory pathways that have a very important role in…”
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Cyclic Guanosine 5′-Monophosphate-Dependent Protein Kinase II Is Induced by Luteinizing Hormone and Progesterone Receptor-Dependent Mechanisms in Granulosa Cells and Cumulus Oocyte Complexes of Ovulating Follicles by Sriraman, Venkataraman, Rudd, Michael D, Lohmann, Suzanne M, Mulders, Sabine M, Richards, JoAnne S

“…Cyclic GMP (cGMP)-dependent protein kinase II (Prkg2, cGK II) was identified as a potential target of the progesterone receptor (Nr3c3) in the mouse ovary…”
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Analysis of Drosophila cGMP-dependent Protein Kinases and Assessment of Their in Vivo Roles by Targeted Expression in a Renal Transporting Epithelium by MacPherson, Matthew R., Lohmann, Suzanne M., Davies, Shireen-A.

“…cGMP-dependent protein kinase (cGK) forms encoded by the dg2 (for) gene are implicated in behavior and epithelial transport in Drosophila melanogaster. Here,…”
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Cyclic GMP-dependent Protein Kinase Iα Attenuates Necrosis and Apoptosis Following Ischemia/Reoxygenation in Adult Cardiomyocyte by Das, Anindita, Smolenski, Albert, Lohmann, Suzanne M., Kukreja, Rakesh C.

“…Cyclic GMP-dependent protein kinases protein kinase G (PKG) Iα and PKGIβ are major mediators of cGMP signaling in the cardiovascular system. PKGIα is present…”
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Increased effects of C‐type natriuretic peptide on contractility and calcium regulation in murine hearts overexpressing cyclic GMP‐dependent protein kinase I by Wollert, Kai C, Yurukova, Sevdalina, Kilic, Ana, Begrow, Frank, Fiedler, Beate, Gambaryan, Stepan, Walter, Ulrich, Lohmann, Suzanne M, Kuhn, Michaela

“…C‐type natriuretic peptide (CNP) and its receptor guanylyl cyclase (GC‐B) are expressed in the heart and modulate cardiac contractility in a cGMP‐dependent…”
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Cyclic GMP-Dependent Protein Kinases and the Cardiovascular System: Insights From Genetically Modified Mice by Feil, Robert, Lohmann, Suzanne M, de Jonge, Hugo, Walter, Ulrich, Hofmann, Franz

“…ABSTRACT—Signaling cascades initiated by nitric oxide (NO) and natriuretic peptides (NPs) play an important role in the maintenance of cardiovascular…”
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Presynaptic and Postsynaptic Roles of NO, cGK, and RhoA in Long-Lasting Potentiation and Aggregation of Synaptic Proteins by Wang, Hong-Gang, Lu, Fang-Min, Jin, Iksung, Udo, Hiroshi, Kandel, Eric R., de Vente, Jan, Walter, Ulrich, Lohmann, Suzanne M., Hawkins, Robert D., Antonova, Irina

“…Recent results suggest that long-lasting potentiation at hippocampal synapses involves the rapid formation of clusters or puncta of presynaptic as well as…”
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Cyclic GMP-dependent Protein Kinase Signaling Pathway Inhibits RhoA-induced Ca2+ Sensitization of Contraction in Vascular Smooth Muscle by Sauzeau, Vincent, Le Jeune, Hélène, Cario-Toumaniantz, Chrystelle, Smolenski, Albert, Lohmann, Suzanne M., Bertoglio, Jacques, Chardin, Pierre, Pacaud, Pierre, Loirand, Gervaise

“…The potent vasodilator action of cyclic GMP-dependent protein kinase (cGK) involves decreasing the Ca2+ sensitivity of contraction of smooth muscle via…”
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Tracking functions of cGMP-dependent protein kinases (cGK) by Lohmann, Suzanne M, Walter, Ulrich

“…The options available for distinguishing the effects of cGMP mediated by cGK versus those mediated by other cGMP targets are discussed and evaluated. These…”
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Distinct and specific functions of cGMP-dependent protein kinases by Lohmann, Suzanne M., Vaandrager, Arie B., Smolenski, Albert, Walter, Ulrich, De Jonge, Hugo R.

“…cGMP-dependent protein kinases I and II conduct signals from widespread signaling systems. Whereas the type I kinase mediates numerous effects of natriuretic…”
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Endothelial Nitric-oxide Synthase (Type III) Is Activated and Becomes Calcium Independent upon Phosphorylation by Cyclic Nucleotide-dependent Protein Kinases by Butt, Elke, Bernhardt, Manfred, Smolenski, Albert, Kotsonis, Peter, Fröhlich, Lothar G., Sickmann, Albert, Meyer, Helmut E., Lohmann, Suzanne M., Schmidt, Harald H.H.W.

“…Endothelial nitric-oxide synthase (NOS-III) is defined as being strictly dependent on Ca2+/calmodulin (CaM) for activity, although NO release from endothelial…”
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Regulation of Human Endothelial Cell Focal Adhesion Sites and Migration by cGMP-dependent Protein Kinase I by Smolenski, Albert, Poller, Wolfgang, Walter, Ulrich, Lohmann, Suzanne M.

“…cGMP-dependent protein kinase type I (cGK I), a major constituent of the atrial natriuretic peptide (ANP)/nitric oxide/cGMP signal transduction pathway,…”
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Presynaptic Role of cGMP-Dependent Protein Kinase during Long-Lasting Potentiation by Arancio, Ottavio, Antonova, Irina, Gambaryan, Stepan, Lohmann, Suzanne M, Wood, Jason S, Lawrence, David S, Hawkins, Robert D

“…Previous research has suggested that cGMP-dependent protein kinases (cGKs) may play a role in long-term potentiation in hippocampus, but their site of action…”
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The nitric oxide and cGMP signal transduction system: regulation and mechanism of action by Schmidt, H H, Lohmann, S M, Walter, U

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