Search Results - "Lohi, H"

A large case-control study indicates a breed-specific predisposition to feline tooth resorption by Vapalahti, K., Neittaanmäki, H., Lohi, H., Virtala, A.-M.

“…Tooth resorption (TR) is one of the most common dental diseases of cats. It is a painful condition leading to tooth loss. The etiology of TR remains unclear,…”
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Diagnostic Utility of Wireless Video‐Electroencephalography in Unsedated Dogs by James, F.M.K., Cortez, M.A., Monteith, G., Jokinen, T.S., Sanders, S., Wielaender, F., Fischer, A., Lohi, H.

“…Background Poor agreement between observers on whether an unusual event is a seizure drives the need for a specific diagnostic tool provided by…”
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The canine era: the rise of a biomedical model by van Steenbeek, F. G., Hytönen, M. K., Leegwater, P. A. J., Lohi, H.

“…Summary Since the annotation of its genome a decade ago, the dog has proven to be an excellent model for the study of inherited diseases. A large variety of…”
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Balancing selection and heterozygote advantage in major histocompatibility complex loci of the bottlenecked Finnish wolf population by Niskanen, A. K, Kennedy, L. J, Ruokonen, M, Kojola, I, Lohi, H, Isomursu, M, Jansson, E, Pyhäjärvi, T, Aspi, J

“…Maintaining effective immune response is an essential factor in the survival of small populations. One of the most important immune gene regions is the highly…”
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Breed‐specific reference ranges for standard echocardiographic measurements in salukis by Giraut, S., Häggström, J., Koskinen, L. L. E., Lohi, H., Wiberg, M.

“…Objectives To establish normal reference ranges for standard echocardiographic measurements in Salukis and to examine whether bodyweight, age, gender and heart…”
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Association study reveals novel risk loci for sporadic inclusion body myositis by Johari, M., Arumilli, M., Palmio, J., Savarese, M., Tasca, G., Mirabella, M., Sandholm, N., Lohi, H., Hackman, P., Udd, B.

“…Background and purpose The aim was to identify potential genetic risk factors associated with sporadic inclusion body myositis (sIBM). Methods An association…”
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A novel KRT71 variant in curly‐coated dogs by Salmela, E., Niskanen, J., Arumilli, M., Donner, J., Lohi, H., Hytönen, M. K.

“…Summary Curly fur is a common phenotype in many dog breeds, known to result from a missense variant (c.451C>T) in exon 2 of the keratin 71 (KRT71) gene. During…”
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Two novel genomic regions associated with fearfulness in dogs overlap human neuropsychiatric loci by Sarviaho, R., Hakosalo, O., Tiira, K., Sulkama, S., Salmela, E., Hytönen, M. K., Sillanpää, M. J., Lohi, H.

“…Anxiety disorders are among the leading health issues in human medicine. The complex phenotypic and allelic nature of these traits as well as the challenge of…”
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Two MC1R loss‐of‐function alleles in cream‐coloured Australian Cattle Dogs and white Huskies by Dürig, N., Letko, A., Lepori, V., Hadji Rasouliha, S., Loechel, R., Kehl, A., Hytönen, M. K., Lohi, H., Mauri, N., Dietrich, J., Wiedmer, M., Drögemüller, M., Jagannathan, V., Schmutz, S. M., Leeb, T.

“…Summary Loss‐of‐function variants in the MC1R gene cause recessive red or yellow coat‐colour phenotypes in many species. The canine MC1R:c.916C>T (p.Arg306Ter)…”
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Ventricular arrhythmia and sudden cardiac death in young Leonbergers by Wiberg, M., Niskanen, J.E., Hytönen, M., Dillard, K., Hagner, K., Anttila, M., Lohi, H.

“…To describe unexpected sudden cardiac death (SCD) in young Leonbergers (<3 years) and to review the circumstances before death and necropsy findings; to…”
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Absence Seizures as a Feature of Juvenile Myoclonic Epilepsy in Rhodesian Ridgeback Dogs by Wielaender, F., James, F.M.K., Cortez, M.A., Kluger, G., Neßler, J.N., Tipold, A., Lohi, H., Fischer, A.

“…Myoclonic epilepsy in Rhodesian Ridgeback (RR) dogs is characterized by myoclonic seizures occurring mainly during relaxation periods, a juvenile age of onset…”
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A novel genomic region on chromosome 11 associated with fearfulness in dogs by Sarviaho, R., Hakosalo, O., Tiira, K., Sulkama, S., Niskanen, J. E., Hytönen, M. K., Sillanpää, M. J., Lohi, H.

“…The complex phenotypic and genetic nature of anxieties hampers progress in unravelling their molecular etiologies. Dogs present extensive natural variation in…”
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Behavioral Abnormalities in Lagotto Romagnolo Dogs with a History of Benign Familial Juvenile Epilepsy: A Long‐Term Follow‐Up Study by Jokinen, T.S., Tiira, K., Metsähonkala, L., Seppälä, E.H., Hielm‐Björkman, A., Lohi, H., Laitinen‐Vapaavuori, O.

“…Background Lagotto Romagnolo (LR) dogs with benign juvenile epilepsy syndrome often experience spontaneous remission of seizures. The long‐term outcome in…”
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Exploration of known stereotypic behaviour-related candidate genes in equine crib-biting by Hemmann, K., Ahonen, S., Raekallio, M., Vainio, O., Lohi, H.

“…Crib-biting in horses is a stereotypic oral behaviour. Genetic susceptibility has been suggested on a causal basis, together with environmental factors such as…”
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Deep sequencing of a candidate region harboring the SOX9 gene for the canine XX disorder of sex development by Nowacka‐Woszuk, J., Szczerbal, I., Pausch, H., Hundi, S., Hytönen, M. K., Grzemski, A., Flisikowski, K., Lohi, H., Switonski, M., Szydlowski, M.

“…Summary A disorder of sex development (DSD) in dogs with female sex chromosomes (78, XX), a lack of the SRY gene and the presence of testes or ovotestes is…”
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Disease Progression and Treatment Response of Idiopathic Epilepsy in Australian Shepherd Dogs by Weissl, J., Hülsmeyer, V., Brauer, C., Tipold, A., Koskinen, L.L., Kyöstilä, K., Lohi, H., Sauter‐Louis, C., Wolf, M., Fischer, A.

“…Background Idiopathic epilepsy (IE) in Australian Shepherds (ASs) occurs worldwide but there is a lack of description of the epilepsy syndrome in this breed…”
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Association study reveals novel genetic risk factors associated with sporadic inclusion body myositis by Johari, M, Arumilli, M, Sandholm, N, Lohi, H, Hackman, P, Udd, B

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MHC variability supports dog domestication from a large number of wolves: high diversity in Asia by Niskanen, A K, Hagström, E, Lohi, H, Ruokonen, M, Esparza-Salas, R, Aspi, J, Savolainen, P

“…The process of dog domestication is still somewhat unresolved. Earlier studies indicate that domestic dogs from all over the world have a common origin in…”
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Paroxysmal Dyskinesia in Border Terriers: Clinical, Epidemiological, and Genetic Investigations by Stassen, Q.E.M., Koskinen, L.L.E., van Steenbeek, F.G., Seppälä, E.H., Jokinen, T.S., Prins, P.G.M., Bok, H.G.J., Zandvliet, M.M.J.M., Vos‐Loohuis, M., Leegwater, P.A.J., Lohi, H.

“…Background In the last decade, a disorder characterized by episodes of involuntary movements and dystonia has been recognized in Border Terriers. Objectives To…”
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Interbreed variation in serum serotonin (5-hydroxytryptamine) concentration in healthy dogs by Höglund, K., Häggström, J., Hanås, S., Merveille, A.-C., Gouni, V., Wiberg, M., Lundgren Willesen, J., Entee, K.Mc, Mejer Sørensen, L., Tiret, L., Seppälä, E.H., Lohi, H., Chetboul, V., Fredholm, M., Lequarré, A.-S., Ljungvall, I.

“…Serotonin (5-hydroxytryptamine [5-HT]) has several biological functions. In different species, excessive 5-HT has been linked to valvular lesions, similar to…”
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