Search Results - "Lohan, Silke"
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Application of 233 nm far-UVC LEDs for eradication of MRSA and MSSA and risk assessment on skin models
Published in Scientific reports (16-02-2022)“…A newly developed UVC LED source with an emission wavelength of 233 nm was proved on bactericidal efficacy and skin tolerability. The bactericidal efficacy was…”
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Evidence of the protective effect of anti-pollution products against oxidative stress in skin ex vivo using EPR spectroscopy and autofluorescence measurements
Published in European journal of pharmaceutics and biopharmaceutics (01-04-2024)“…[Display omitted] The concentration of air pollution is gradually increasing every year so that daily skin exposure is unavoidable. Dietary supplements and…”
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Skin tolerant inactivation of multiresistant pathogens using far-UVC LEDs
Published in Scientific reports (19-07-2021)“…Multiresistant pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) cause serious postoperative infections. A skin tolerant far-UVC (< 240 nm)…”
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Radical formation in skin and preclinical characterization of a novel medical plasma device for dermatology after single application
Published in Free radical biology & medicine (14-11-2024)“…Cold atmospheric plasma (CAP) enables painless tissue treatment by producing reactive species including excited molecules and charged particles and is of great…”
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Significance of melanin distribution in the epidermis for the protective effect against UV light
Published in Scientific reports (12-02-2024)“…Melanin, the most abundant skin chromophore, is produced by melanocytes and is one of the key components responsible for mediating the skin’s response to…”
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pH-sensitive Eudragit® L 100 nanoparticles promote cutaneous penetration and drug release on the skin
Published in Journal of controlled release (10-02-2019)“…Nanoparticles (NPs) are promising carriers for dermal and transdermal drug delivery. However, the underlying dynamics of drug release from the NPs, especially,…”
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Oxidative stress coping capacity (OSC) value: Development and validation of an in vitro measurement method for blood plasma using electron paramagnetic resonance spectroscopy (EPR) and vitamin C
Published in Free radical biology & medicine (01-01-2023)“…Oxidative stress as a driver of disease is reinforcing the trend towards supplementation with antioxidants. While antioxidants positively influence the redox…”
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EPR Spectroscopy as a Method for ROS Quantification in the Skin
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…Electron paramagnetic resonance (EPR) spectroscopy is an established method for the measurement of free radicals. Solar radiation is essential for human life…”
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Establishment of a method to expose and measure pollution in excised porcine skin with electron paramagnetic resonance spectroscopy
Published in Ecotoxicology and environmental safety (01-12-2022)“…Health problems associated with the amount of air pollutants are increasing worldwide. Pollution damages not only the lungs; it also has an impact on skin…”
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10
Irradiation of human oral mucosa by 233 nm far UV-C LEDs for the safe inactivation of nosocomial pathogens
Published in Scientific reports (16-12-2023)“…The inactivation of multi resistant pathogens is an important clinical need. One approach is UV-C irradiation, which was previously not possible in vivo due to…”
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ROS production and glutathione response in keratinocytes after application of β-carotene and VIS/NIR irradiation
Published in Chemico-biological interactions (25-01-2018)“…The skin is exposed to many stress factors which, in turn, can promote a shift of the antioxidant (AO) network towards the prooxidative side, supporting the…”
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Evaluation of DNA lesions and radicals generated by a 233 nm far-UVC LED in superficial ex vivo skin wounds
Published in Journal of photochemistry and photobiology. B, Biology (01-08-2023)“…The application of a far-ultraviolet C (UVC) light emitting diode (LED) of 233 nm showed significant bactericidal efficacy at an applied dose between 20 and…”
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13
Carotenoids in Human Skin In Vivo: Antioxidant and Photo-Protectant Role against External and Internal Stressors
Published in Antioxidants (01-07-2022)“…The antioxidant system of the human body plays a crucial role in maintaining redox homeostasis and has an important protective function. Carotenoids have…”
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14
Ultra-small lipid nanoparticles promote the penetration of coenzyme Q10 in skin cells and counteract oxidative stress
Published in European journal of pharmaceutics and biopharmaceutics (01-01-2015)“…[Display omitted] •Uptake of CoQ10 into HaCaTs by ultra-small lipid nanoparticles (usNLC).•usNLC were distributed within the cytoplasm of HaCaT cells.•Electron…”
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15
Free radicals induced by sunlight in different spectral regions - in vivo versus ex vivo study
Published in Experimental dermatology (01-05-2016)“…Sunlight represents an exogenous factor stimulating formation of free radicals which can induce cell damage. To assess the effect of the different spectral…”
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Eco-friendly sunscreen formulation based on starches and PEG-75 lanolin increases the antioxidant capacity and the light scattering activity in the visible light
Published in Journal of photochemistry and photobiology. B, Biology (01-09-2021)“…Most modern sunscreens contain physical filters, which scatter the sunlight, increasing the photons' pathway in the upper stratum corneum. This effect can lead…”
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Treatment of the Candida subspecies Candida albicans and Candida parapsilosis with two far‐UVC sources to minimise mycoses in clinical practice
Published in Mycoses (01-01-2023)“…Fungal infections have increased considerably over the last decades, becoming progressively resistant to common drugs. UVC light has shown microbiological…”
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Insight into the redox status of inflammatory skin equivalents as determined by EPR spectroscopy
Published in Chemico-biological interactions (01-09-2019)“…Atopic dermatitis (AD) is a chronic inflammatory skin disease whose pathogenesis is still not fully understood. Since inflammatory processes correlate with…”
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Far-UVC- and UVB-induced DNA damage depending on skin type
Published in Experimental dermatology (01-09-2023)“…Far-UVC radiation sources of wavelengths 222 nm and 233 nm represent an interesting potential alternative for the antiseptic treatment of the skin due to their…”
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A Dual Fluorescence–Spin Label Probe for Visualization and Quantification of Target Molecules in Tissue by Multiplexed FLIM–EPR Spectroscopy
Published in Angewandte Chemie International Edition (25-06-2021)“…Simultaneous visualization and concentration quantification of molecules in biological tissue is an important though challenging goal. The advantages of…”
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