Search Results - "Loh, Kah Poh"
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Evaluating the association of frailty with communication about aging‐related concerns between older patients with advanced cancer and their oncologists
Published in Cancer (01-03-2022)“…Background A geriatric assessment (GA) intervention improves communication about aging‐related concerns, but its effect on communication in patients with…”
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Defining Undertreatment and Overtreatment in Older Adults With Cancer: A Scoping Literature Review
Published in Journal of clinical oncology (01-08-2020)“…The terms undertreatment and overtreatment are often used to describe inappropriate management of older adults with cancer. We conducted a comprehensive…”
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The longitudinal relationship between immune cell profiles and frailty in patients with breast cancer receiving chemotherapy
Published in Breast cancer research : BCR (05-02-2021)“…Frailty is associated with an increased risk of chemotherapy toxicity. Cellular markers of inflammation can help identify patients with frailty…”
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Systematic Review of Randomized Controlled Trials of Exercise Interventions Using Digital Activity Trackers in Patients With Cancer
Published in Journal of the National Comprehensive Cancer Network (01-01-2019)“…Exercise can ameliorate cancer- and treatment-related toxicities, but poor adherence to exercise regimens is a barrier. Exercise interventions using digital…”
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How Genetics Can Drive Initial Therapy Choices for Older Patients with Acute Myeloid Leukemia
Published in Current treatment options in oncology (01-08-2022)“…Opinion statement Treatment of older adults with acute myeloid leukemia (AML) is challenging. Therapy decisions must be guided by multiple factors including…”
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The shared uncertainty experience of older adults with advanced cancer and their caregivers
Published in Psycho-oncology (Chichester, England) (01-06-2022)“…Objective One primary source of psychological distress in patients with cancer and their caregivers is uncertainty. However, the uncertainty trajectory and its…”
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Associations of interleukin-6 with functional trajectories in older adults with cancer: Findings from the Health, Aging, and Body Composition Study
Published in Experimental gerontology (15-06-2023)“…Elevated markers of inflammation, such as interleukin-6 (IL-6), are associated with aging, cancer, and functional decline. We assessed the association of…”
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Exercise and inflammatory cytokine regulation among older adults with myeloid malignancies
Published in Experimental gerontology (01-03-2024)“…Tumor necrosis factor (TNF)α is a major regulator of inflammation. However, the epigenetic regulation of TNFα in the context of an exercise intervention among…”
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Influence of Yoga on Cancer-Related Fatigue and on Mediational Relationships Between Changes in Sleep and Cancer-Related Fatigue: A Nationwide, Multicenter Randomized Controlled Trial of Yoga in Cancer Survivors
Published in Integrative cancer therapies (01-06-2019)“…Background: Cancer-related fatigue (CRF) often co-occurs with sleep disturbance and is one of the most pervasive toxicities resulting from cancer and its…”
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Nutritional impairment, psychological health and quality of life among older adults with advanced cancer: A secondary analysis of a randomized clinical trial
Published in Cancer medicine (Malden, MA) (01-06-2024)“…Background Nutritional impairment is associated with treatment toxicity and worse overall survival in patients with cancer. We aimed to (1) evaluate the…”
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Advance care planning in older patients with acute myeloid leukemia and myelodysplastic syndromes
Published in Journal of geriatric oncology (01-01-2023)“…Older patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) have worse survival rates compared to younger patients, and experience…”
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Exercise and epigenetic ages in older adults with myeloid malignancies
Published in European journal of medical research (30-05-2023)“…Older adults with myeloid malignancies are susceptible to treatment-related toxicities. Accelerated DNAm age, or the difference between DNA methylation (DNAm)…”
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An Unusual Cause of Delirium and Debility: Refractory Hypercalcemia in a Man with B-Cell Prolymphocytic Leukemia
Published in Journal of the American Geriatrics Society (JAGS) (01-10-2014)Get full text
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Use of cyclin-dependent kinase 4/6 (CDK4/6) inhibitors in older patients with ER-positive HER2-negative breast cancer: Young International Society of Geriatric Oncology review paper
Published in Therapeutic Advances in Medical Oncology (01-01-2018)“…The current standard of care for the management of estrogen receptor (ER)-positive and human epidermal growth factor receptor 2 (HER2)-negative breast cancer…”
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Novel therapies in platinumrefractory metastatic germ cell tumor: a case report with a focus on a PD-1 inhibitor
Published in Rare tumors (03-07-2017)“…Testicular germ cell tumor (GCT) is the most common malignancy in young males between the ages of 15 to 35 years. Although the overall cure rate of GCTs…”
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Patient‐centered communication tool for older patients with acute myeloid leukemia, their caregivers, and oncologists: A single‐arm pilot study
Published in Cancer medicine (Malden, MA) (01-04-2023)“…Background In a single‐arm pilot study, we assessed the feasibility and usefulness of an innovative patient‐centered communication tool (UR‐GOAL tool) that…”
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Characterizing cancer cachexia in the geriatric oncology population
Published in Journal of geriatric oncology (01-05-2019)“…Cancer cachexia, characterized by weight loss and sarcopenia, leads to a decline in physical function and is associated with poorer survival. Cancer cachexia…”
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Clinicians' Perspectives on the Telehealth Serious Illness Care Program for Older Adults With Myeloid Malignancies: Single-Arm Pilot Study
Published in JMIR formative research (27-06-2024)“…Serious illness conversations may help patients avoid unwanted treatments. We previously piloted the telehealth Serious Illness Care Program (SICP) for older…”
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128 A single-arm pilot study of an adapted Serious Illness Care Program for older patients with acute myeloid leukemia and myelodysplastic syndromes
Published in Journal of clinical and translational science (01-04-2023)“…OBJECTIVES/GOALS: We adapted the Serious Illness Care Program (SICP), an evidence-based intervention designed to promote early serious illness conversation, to…”
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Geriatric oncology research at the 2019 American Geriatrics Society (AGS) annual meeting: Joint perspectives from the Young International Society of Geriatric Oncology (SIOG) and AGS Cancer and Aging Special Interest Group
Published in Journal of geriatric oncology (01-11-2019)Get full text
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