Search Results - "Loh, H H"

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    A leptin–BDNF pathway regulating sympathetic innervation of adipose tissue by Wang, Putianqi, Loh, Ken H., Wu, Michelle, Morgan, Donald A., Schneeberger, Marc, Yu, Xiaofei, Chi, Jingyi, Kosse, Christin, Kim, Damian, Rahmouni, Kamal, Cohen, Paul, Friedman, Jeffrey

    Published in Nature (London) (30-07-2020)
    “…Mutations in the leptin gene ( ob ) result in a metabolic disorder that includes severe obesity 1 , and defects in thermogenesis 2 and lipolysis 3 , both of…”
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    Unidirectional Cross-Activation of GRPR by MOR1D Uncouples Itch and Analgesia Induced by Opioids by Liu, Xian-Yu, Liu, Zhong-Chun, Sun, Yan-Gang, Ross, Michael, Kim, Seungil, Tsai, Feng-Fang, Li, Qi-Fang, Jeffry, Joseph, Kim, Ji-Young, Loh, Horace H., Chen, Zhou-Feng

    Published in Cell (14-10-2011)
    “…Spinal opioid-induced itch, a prevalent side effect of pain management, has been proposed to result from pain inhibition. We now report that the μ-opioid…”
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    Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts by Loh, Ken H., Stawski, Philipp S., Draycott, Austin S., Udeshi, Namrata D., Lehrman, Emily K., Wilton, Daniel K., Svinkina, Tanya, Deerinck, Thomas J., Ellisman, Mark H., Stevens, Beth, Carr, Steven A., Ting, Alice Y.

    Published in Cell (25-08-2016)
    “…Cellular compartments that cannot be biochemically isolated are challenging to characterize. Here we demonstrate the proteomic characterization of the synaptic…”
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    The Q175 mouse model of Huntington's disease shows gene dosage- and age-related decline in circadian rhythms of activity and sleep by Loh, Dawn H, Kudo, Takashi, Truong, Danny, Wu, Yingfei, Colwell, Christopher S

    Published in PloS one (30-07-2013)
    “…Sleep and circadian disruptions are commonly reported by patients with neurodegenerative diseases, suggesting these may be an endophenotype of the disorders…”
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    Built environment and physical activity among adolescents: the moderating effects of neighborhood safety and social support by Loh, Venurs H Y, Veitch, Jenny, Salmon, Jo, Cerin, Ester, Thornton, Lukar, Mavoa, Suzanne, Villanueva, Karen, Timperio, Anna

    “…Increasing emphasis has been placed on improving physical activity levels through multilevel interventions. This study aims to examine moderating effects of…”
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    Precision Spectroscopy of Polarized Molecules in an Ion Trap by Loh, H., Cossel, K. C., Grau, M. C, Ni, K.-K., Meyer, E. R., Bohn, J. L, Ye, J., Cornell, E. A.

    “…Polar molecules are desirable systems for quantum simulations and cold chemistry. Molecular ions are easily trapped, but a bias electric field applied to…”
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    PINK1 cleavage at position A103 by the mitochondrial protease PARL by DEAS, Emma, PLUN-FAVREAU, Helene, ABRAMOV, Andrey Y, WOOD, Nicholas W, GANDHI, Sonia, DESMOND, Howard, KJAER, Svend, LOH, Samantha H. Y, RENTON, Alan E. M, HARVEY, Robert J, WHITWORTH, Alexander J, MARTINS, L. Miguel

    Published in Human molecular genetics (01-03-2011)
    “…Mutations in PTEN-induced kinase 1 (PINK1) cause early onset autosomal recessive Parkinson's disease (PD). PINK1 is a 63 kDa protein kinase, which exerts a…”
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    Loss of PRC2 subunits primes lineage choice during exit of pluripotency by Loh, Chet H., van Genesen, Siebe, Perino, Matteo, Bark, Magnus R., Veenstra, Gert Jan C.

    Published in Nature communications (30-11-2021)
    “…Polycomb Repressive Complex 2 (PRC2) is crucial for the coordinated expression of genes during early embryonic development, catalyzing histone H3 lysine 27…”
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    Role of T helper 17 cells and T regulatory cells in alopecia areata: comparison of lesion and serum cytokine between controls and patients by Loh, S.‐H., Moon, H.‐N., Lew, B.‐L., Sim, W.‐Y.

    “…Background Alopecia areata (AA) is an organ‐specific autoimmune disease with T‐cell‐mediated attack of hair follicle autoantigens. As T helper 17 (Th17) cells…”
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    Development and Validation of a Tool to Screen for Cognitive Frailty Among Community-Dwelling Elders by Tseng, S.-H., Liu, L.-K., Peng, Li-Ning, Wang, P.-N., Loh, C.-H., Chen, Liang-Kung

    Published in The Journal of nutrition, health & aging (01-11-2019)
    “…Objectives Reciprocal age-related impairments in physical and cognitive functioning have been termed ‘cognitive frailty’, which is associated with adverse…”
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    Long-Term Mortality Risk in Older Adults with Sarcopenia: An 11-Year Prospective Cohort Study Comparing AWGS 2014 and AWGS 2019 Guidelines for Enhanced Clinical Utility and Accurate Risk Prediction by Liang, C.-K., Peng, L.-N., Lin, M.-H., Loh, C.-H., Lee, Wei-Ju, Hsiao, F.-Y., Chen, L.-K.

    Published in The Journal of nutrition, health & aging (01-07-2023)
    “…Objectives To discern the diagnostic accuracy between the updated diagnostic consensus of the Asian Working Group for Sarcopenia (AWGS) in 2019 (AWGS 2019) and…”
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    Acute myocardial infarction and myocarditis following COVID-19 vaccination by Aye, Y N, Mai, A S, Zhang, A, Lim, O Z H, Lin, N, Ng, C H, Chan, M Y, Yip, J, Loh, P -H, Chew, N W S

    Published in QJM : An International Journal of Medicine (29-04-2023)
    “…Abstract Emerging reports raise concerns on the potential association between the COVID-19 vaccines and cardiac manifestations. We sought to evaluate cardiac…”
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    Parp mutations protect from mitochondrial toxicity in Alzheimer’s disease by Yu, Yizhou, Fedele, Giorgio, Celardo, Ivana, Loh, Samantha H. Y., Martins, L. Miguel

    Published in Cell death & disease (25-06-2021)
    “…Alzheimer’s disease is the most common age-related neurodegenerative disorder. Familial forms of Alzheimer’s disease associated with the accumulation of a…”
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    Circadian dysfunction in a mouse model of Parkinson's disease by Kudo, Takashi, Loh, Dawn H., Truong, Danny, Wu, Yingfei, Colwell, Christopher S.

    Published in Experimental neurology (01-11-2011)
    “…Many Parkinson's disease (PD) patients exhibit sleep disorders as part of their symptoms with evidence suggesting that REM sleep disorders may be intimately…”
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    Malignant Transformation in Porokeratosis Ptychotropica: A Systematic Review by Loh, Chee H, Tan, Chris L, Tan, Kong B, Sudhoff, Holger, Goon, Peter

    Published in Acta dermato-venereologica (10-10-2024)
    “…Porokeratosis ptychotropica (PP) is a rare and unusual variant of porokeratosis. There is a dearth of information on the natural history, epidemiology, and…”
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    Transcriptional and Epigenetic Regulation of Opioid Receptor Genes: Present and Future by WEI, Li-Na, LOH, Horace H

    “…Three opioid receptors (ORs) are known: μ opioid receptors (MORs), δ opioid receptors (DORs), and κ opioid receptors (KORs). Each is encoded by a distinct…”
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    Targeting Transmission Pathways for Emerging Zoonotic Disease Surveillance and Control by Loh, Elizabeth H, Zambrana-Torrelio, Carlos, Olival, Kevin J, Bogich, Tiffany L, Johnson, Christine K, Mazet, Jonna A K, Karesh, William, Daszak, Peter

    “…We used literature searches and a database of all reported emerging infectious diseases (EIDs) to analyze the most important transmission pathways (e.g.,…”
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