Search Results - "Loghin, Monica E."
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Donepezil for Irradiated Brain Tumor Survivors: A Phase III Randomized Placebo-Controlled Clinical Trial
Published in Journal of clinical oncology (20-05-2015)“…Neurotoxic effects of brain irradiation include cognitive impairment in 50% to 90% of patients. Prior studies have suggested that donepezil, a neurotransmitter…”
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Phase 1 lead‐in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma
Published in Cancer (01-02-2019)“…Background Repurposed memantine, mefloquine, and metformin have putative anticancer activity. The objective of this phase 1 study was to determine the maximum…”
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Toxicity in the era of immune checkpoint inhibitor therapy
Published in Frontiers in immunology (2024)“…Immune checkpoint inhibitors (ICIs) reinvigorate anti-tumor immune responses by disrupting co-inhibitory immune checkpoint molecules such as programmed cell…”
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Chimeric antigen receptor T-cell therapy — assessment and management of toxicities
Published in Nature reviews. Clinical oncology (01-01-2018)“…Key Points Chimeric antigen receptor (CAR)-T-cell therapy is a promising approach for the treatment of refractory malignancies, but is associated with unique…”
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Posterior reversible encephalopathy syndrome in cancer patients: a single institution retrospective study
Published in Journal of neuro-oncology (01-05-2016)“…Posterior reversible encephalopathy syndrome (PRES) is a clinico-radiologic entity. Its management and outcome in the oncology population is limited because it…”
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Phase I Study of Temozolomide and Irinotecan for Recurrent Malignant Gliomas in Patients Receiving Enzyme-Inducing Antiepileptic Drugs: A North American Brain Tumor Consortium Study
Published in Clinical cancer research (01-12-2007)“…Purpose: To determine the maximum tolerated dose of irinotecan when administrated with temozolomide every 28 days, in patients with recurrent malignant glioma…”
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A randomized phase II trial of standard dose bevacizumab versus low dose bevacizumab plus lomustine (CCNU) in adults with recurrent glioblastoma
Published in Journal of neuro-oncology (01-09-2016)“…Antiangiogenic therapy can rapidly reduce vascular permeability and cerebral edema but high doses of bevacizumab may induce selective pressure to promote…”
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Randomized phase II adjuvant factorial study of dose-dense temozolomide alone and in combination with isotretinoin, celecoxib, and/or thalidomide for glioblastoma
Published in Neuro-oncology (Charlottesville, Va.) (01-02-2015)“…Chemoradiation, followed by adjuvant temozolomide, is the standard treatment for newly diagnosed glioblastoma. Adding other active agents may enhance treatment…”
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Posterior Reversible Encephalopathy Syndrome: A Neurologic Phenomenon in Cancer Patients
Published in Current oncology reports (01-05-2014)“…Posterior reversible encephalopathy syndrome is a well-recognized entity associated with a variety of benign and malignant conditions. This syndrome typically…”
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Accelerated tumor progression after COVID-19 infection in patients with glioblastoma: A retrospective case-control study
Published in Neuro-oncology practice (01-08-2024)“…We observed rapid tumor progression following COVID-19 infection among patients with glioblastoma and sought to systematically characterize their disease…”
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Prolonged survival in adult neurofibromatosis type I patients with recurrent high-grade gliomas treated with bevacizumab
Published in Journal of neurology (01-08-2014)“…Astrocytic tumors, especially optic pathway pilocytic astrocytomas, are common in pediatric NF1 patients. High-grade gliomas (HGGs) appear to be rare in adult…”
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Spinal cord compression in cancer patients: Review of diagnosis and treatment
Published in Current oncology reports (2008)“…Spinal cord compression (SCC) is a well-known complication in cancer patients, with an enormous potential impact on quality of life. In most cases, treatment…”
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Distinct molecular and immune hallmarks of inflammatory arthritis induced by immune checkpoint inhibitors for cancer therapy
Published in Nature communications (12-04-2022)“…Immune checkpoint inhibitors are associated with immune-related adverse events (irAEs), including arthritis (arthritis-irAE). Management of arthritis-irAE is…”
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A Rare Case of Primary Angiitis of the Central Nervous System (PACNS) Associated with Metastatic Prostate Cancer (P3.155)
Published in Neurology (18-04-2017)“…Abstract only…”
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