Search Results - "Logeart‐Avramoglou, D."
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Survival and function of mesenchymal stem cells (MSCs) depend on glucose to overcome exposure to long‐term, severe and continuous hypoxia
Published in Journal of cellular and molecular medicine (01-07-2011)“…Use of mesenchymal stem cells (MSCs) has emerged as a potential new treatment for various diseases but has generated marginally successful results. A…”
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Engineering bone: challenges and obstacles
Published in Journal of cellular and molecular medicine (01-01-2005)“…Repair of large bone defects is still a challenge for the orthopaedic, reconstructive and maxillo‐facial surgeon. Availability of pluripotent stem cells from…”
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Human mesenchymal stem cell responses to hydrostatic pressure and shear stress
Published in European cells & materials (19-02-2016)“…The effects of mechanical stimuli to which cells are exposed in vivo are, at best, incompletely understood; in this respect, gene-level information regarding…”
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Assessment of a polyelectrolyte multilayer film coating loaded with BMP-2 on titanium and PEEK implants in the rabbit femoral condyle
Published in Acta biomaterialia (01-05-2016)“…[Display omitted] The aim of this study was to evaluate the osseointegration of titanium implants (Ti-6Al-4V, noted here TA6V) and poly(etheretherketone) PEEK…”
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Strategies for improving the efficacy of bioengineered bone constructs: a perspective
Published in Osteoporosis international (01-06-2011)“…Bioengineered bone scaffolds are intended for use in large bone defects. Successful bone constructs should stimulate and support both the onset and the…”
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Optimization of a gene electrotransfer method for mesenchymal stem cell transfection
Published in Gene therapy (01-04-2008)“…Gene electrotransfer is an efficient and reproducible nonviral gene transfer technique useful for the nonpermanent expression of therapeutic transgenes. The…”
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A comparative study of tissue-engineered constructs from Acropora and Porites coral in a large animal bone defect model
Published in Bone & joint research (01-04-2017)“…To compare the therapeutic potential of tissue-engineered constructs (TECs) combining mesenchymal stem cells (MSCs) and coral granules from either or to repair…”
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An assay for the determination of biologically active bone morphogenetic proteins using cells transfected with an inhibitor of differentiation promoter-luciferase construct
Published in Analytical biochemistry (01-02-2006)“…Bone morphogenetic proteins (BMPs) control cell fate by regulating gene expression, especially inhibitor of differentiation (Id) genes. This property has been…”
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Sustained and promoter dependent bone morphogenetic protein expression by rat mesenchymal stem cells after BMP-2 transgene electrotransfer
Published in European cells & materials (09-07-2012)“…Transplantation of mesenchymal stem cells (MSCs) with electrotransferred bone morphogenetic protein-2 (BMP-2) transgene is an attractive therapeutic modality…”
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The role of the seeding density on the HMSC fate in bone tissue engineered constructs in vivo
Published in Bone (New York, N.Y.) (01-06-2010)Get full text
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In vivo molecular evidence of delayed titanium implant osseointegration in compromised bone
Published in Bone (New York, N.Y.) (01-05-2011)Get full text
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Validation of a skeletal unloading model for assessment of the Impact of bone quality on initial implant osseointegration
Published in Bone (New York, N.Y.) (01-06-2010)Get full text
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The performance of BMP-2 loaded TCP/HAP porous ceramics with a polyelectrolyte multilayer film coating
Published in Biomaterials (01-10-2011)“…Abstract Delivering rhBMP-2 (recombinant Bone Morphogenic Protein-2) at low but therapeutically efficient dose is one of the current challenges for bone tissue…”
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Nouvelles perspectives dans l’action paracrine et/ou endocrine des BMPs au niveau hypophysaire
Published in Annales d'endocrinologie (01-09-2013)Get full text
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The stability of BMP loaded polyelectrolyte multilayer coatings on titanium
Published in Biomaterials (01-07-2013)“…Abstract Immobilization of bone morphogenetic proteins (BMP) onto material surfaces is a promising, but still challenging, strategy for achieving dependable…”
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Quiescence Preconditioned Human Multipotent Stromal Cells Adopt a Metabolic Profile Favorable for Enhanced Survival under Ischemia
Published in Stem cells (Dayton, Ohio) (01-01-2017)“…A major impediment to the development of therapies with mesenchymal stem cells/multipotent stromal cells (MSC) is the poor survival and engraftment of MSCs at…”
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Hypoxia affects mesenchymal stromal cell osteogenic differentiation and angiogenic factor expression
Published in Bone (New York, N.Y.) (01-04-2007)“…Abstract Mesenchymal stromal cells (MSCs) seeded onto biocompatible scaffolds have been proposed for repairing bone defects. When transplanted in vivo , MSCs…”
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Optimisation des matériaux hybrides à base de cellules souches pour la réparation de grands défauts osseux
Published in Ingénierie et recherche biomédicale (01-04-2012)“…Résumé Les limites imposées par l’autogreffe osseuse ont poussé au développement de nouvelles stratégies pour le traitement des grandes pertes de substances…”
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Ischemia is the prime but not the only cause of human multipotent stromal cell death in tissue-engineered constructs in vivo
Published in Tissue engineering. Part A (01-10-2012)“…Local tissue ischemia is a prime cause responsible for the massive cell death in tissue-engineered (TE) constructs observed postimplantation. To assess the…”
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