Search Results - "Logan, Timothy"
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Metabolism in Human Mesenchymal Stromal Cells: A Missing Link Between hMSC Biomanufacturing and Therapy?
Published in Frontiers in immunology (08-05-2019)“…Human mesenchymal stem cells (hMSCs) are the most commonly-tested adult stem cells in cell therapy. While the initial focus for hMSC clinical applications was…”
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In Vitro Culture Expansion Shifts the Immune Phenotype of Human Adipose-Derived Mesenchymal Stem Cells
Published in Frontiers in immunology (10-03-2021)“…Human mesenchymal stem or stromal cells (hMSCs) are known for their potential in regenerative medicine due to their differentiation abilities, secretion of…”
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Commitment to Aerobic Glycolysis Sustains Immunosuppression of Human Mesenchymal Stem Cells
Published in Stem cells translational medicine (01-01-2019)“…Human mesenchymal stem cells (hMSCs) promote endogenous tissue repair in part by coordinating multiple components of the host immune system in response to…”
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Metabolic Reconfiguration Supports Reacquisition of Primitive Phenotype in Human Mesenchymal Stem Cell Aggregates
Published in Stem cells (Dayton, Ohio) (01-02-2017)“…Spontaneous aggregation and the associated enhancement of stemness have been observed in many anchorage dependent cells. Recently, aggregation of human…”
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A major determinant of cyclophilin dependence and cyclosporine susceptibility of hepatitis C virus identified by a genetic approach
Published in PLoS pathogens (01-09-2010)“…Since the advent of genome-wide small interfering RNA screening, large numbers of cellular cofactors important for viral infection have been discovered at a…”
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Aerosol vertical distribution and optical properties over China from long-term satellite and ground-based remote sensing
Published in Atmospheric chemistry and physics (17-02-2017)“…The seasonal and spatial variations of vertical distribution and optical properties of aerosols over China are studied using long-term satellite observations…”
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Density‐Dependent Metabolic Heterogeneity in Human Mesenchymal Stem Cells
Published in Stem cells (Dayton, Ohio) (01-11-2015)“…Human mesenchymal stem cells (hMSCs) are intrinsically heterogeneous and comprise subpopulations that differ in their proliferation, multi‐potency, and…”
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Aerosol Properties and Their Impacts on Surface CCN at the ARM Southern Great Plains Site during the 2011 Midlatitude Continental Convective Clouds Experiment
Published in Advances in atmospheric sciences (01-02-2018)“…Aerosol particles are of particular importance because of their impacts on cloud development and precipitation processes over land and ocean. Aerosol…”
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NAD+/NADH redox alterations reconfigure metabolism and rejuvenate senescent human mesenchymal stem cells in vitro
Published in Communications biology (15-12-2020)“…Human mesenchymal stem cells (hMSCs) promote endogenous tissue regeneration and have become a promising candidate for cell therapy. However, in vitro culture…”
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Gas chromatography–mass spectrometry analysis of human mesenchymal stem cell metabolism during proliferation and osteogenic differentiation under different oxygen tensions
Published in Journal of biotechnology (01-01-2014)“…•GC–MS was used to investigate glucose metabolism in hMSC and hMSC-derived osteoblasts (hMSC-OS) cultured at 2% or 20% O2.•hMSC and hMSC-OS exhibited different…”
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Ca2+-induced PRE-NMR changes in the troponin complex reveal the possessive nature of the cardiac isoform for its regulatory switch
Published in PloS one (13-11-2014)“…The interaction between myosin and actin in cardiac muscle, modulated by the calcium (Ca2+) sensor Troponin complex (Tn), is a complex process which is yet to…”
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A Conserved Tandem Cyclophilin-Binding Site in Hepatitis C Virus Nonstructural Protein 5A Regulates Alisporivir Susceptibility
Published in Journal of Virology (01-05-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Photopatterning Enzymes on Polymer Monoliths in Microfluidic Devices for Steady-State Kinetic Analysis and Spatially Separated Multi-Enzyme Reactions
Published in Analytical chemistry (Washington) (01-09-2007)“…A method for photopatterning multiple enzymes on porous polymer monoliths within microfluidic devices has been developed and used to perform spatially…”
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14
Error Prevention as Developed in Airlines
Published in International journal of radiation oncology, biology, physics (01-01-2008)“…The airline industry is a high-risk endeavor. Tens of thousands of flights depart each day carrying millions of passengers with the potential for catastrophic…”
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Protein Dynamics and Monomer−Monomer Interactions in AntR Activation by Electron Paramagnetic Resonance and Double Electron−Electron Resonance
Published in Biochemistry (Easton) (16-10-2007)“…The Anthracis repressor (AntR) is a Mn(II)-activated DNA binding protein that is involved in the regulation of Mn(II) homeostasis in Bacillus anthracis. AntR…”
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Assessing Radiative Impacts of African Smoke Aerosols Over the Southeastern Atlantic Ocean
Published in Earth and space science (Hoboken, N.J.) (01-04-2024)“…Biomass burning smoke aerosols are efficient at attenuating incoming solar radiation. The Layered Atlantic Smoke Interactions with Clouds campaign was…”
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Zn(II) Stimulation of Fe(II)-Activated Repression in the Iron-Dependent Repressor from Mycobacterium tuberculosis
Published in Biochemistry (Easton) (19-03-2013)“…Thermodynamic measurements of Fe(II) binding and activation of repressor function in the iron-dependent repressor from Mycobacterium tuberculosis (IdeR) are…”
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A study of Asian dust plumes using satellite, surface, and aircraft measurements during the INTEX-B field experiment
Published in Journal of Geophysical Research: Atmospheres (16-04-2010)“…Asian dust events occur frequently during the boreal spring season. Their optical properties have been analyzed by using a combination of source region…”
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Quantifying Long‐Term Seasonal and Regional Impacts of North American Fire Activity on Continental Boundary Layer Aerosols and Cloud Condensation Nuclei
Published in Earth and space science (Hoboken, N.J.) (01-12-2020)“…An intimate knowledge of aerosol transport is essential in reducing the uncertainty of the impacts of aerosols on cloud development. Data sets from the U.S…”
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Single Peptide Assembly onto a 1.5 nm Au Surface via a Histidine Tag
Published in Journal of the American Chemical Society (03-12-2008)“…Nanoparticle surfaces functionalized with proteins or other biomolecules provide a mechanism for interfacing the unique properties of nanomaterials with…”
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