Search Results - "Logan, Susan K"

Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells by Lee, Eugine, Ha, Susan, Logan, Susan K

“…Despite decades of effort to develop effective therapy and to identify promising new drugs, prostate cancer is lethal once it progresses to…”
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Design of Peptoid-peptide Macrocycles to Inhibit the β-catenin TCF Interaction in Prostate Cancer by Schneider, Jeffrey A., Craven, Timothy W., Kasper, Amanda C., Yun, Chi, Haugbro, Michael, Briggs, Erica M., Svetlov, Vladimir, Nudler, Evgeny, Knaut, Holger, Bonneau, Richard, Garabedian, Michael J., Kirshenbaum, Kent, Logan, Susan K.

“…New chemical inhibitors of protein–protein interactions are needed to propel advances in molecular pharmacology. Peptoids are peptidomimetic oligomers with the…”
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Metformin targets c-MYC oncogene to prevent prostate cancer by Akinyeke, Tunde, Matsumura, Satoko, Wang, Xinying, Wu, Yingjie, Schalfer, Eric D, Saxena, Anjana, Yan, Wenbo, Logan, Susan K, Li, Xin

“…Prostate cancer (PCa) is the second leading cause of cancer-related death in American men and many PCa patients develop skeletal metastasis. Current treatment…”
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Inhibition of androgen receptor and β-catenin activity in prostate cancer by Lee, Eugine, Madar, Aviv, David, Gregory, Garabedian, Michael J., DasGupta, Ramanuj, Logan, Susan K.

“…Androgen receptor (AR) is the major therapeutic target in aggressive prostate cancer. However, targeting AR alone can result in drug resistance and disease…”
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Glucocorticoid Receptor Phosphorylation Differentially Affects Target Gene Expression by Chen, Weiwei, Dang, Thoa, Blind, Raymond D, Wang, Zhen, Cavasotto, Claudio N, Hittelman, Adam B, Rogatsky, Inez, Logan, Susan K, Garabedian, Michael J

“…The glucocorticoid receptor (GR) is phosphorylated at multiple sites within its N terminus (S203, S211, S226), yet the role of phosphorylation in receptor…”
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RIP-seq reveals LINE-1 ORF1p association with p-body enriched mRNAs by Briggs, Erica M, McKerrow, Wilson, Mita, Paolo, Boeke, Jef D, Logan, Susan K, Fenyö, David

“…Long INterspersed Element-1 (LINE-1) is an autonomous retroelement able to "copy-and-paste" itself into new loci of the host genome through a process called…”
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Analysis of URI nuclear interaction with RPB5 and components of the R2TP/prefoldin-like complex by Mita, Paolo, Savas, Jeffrey N, Ha, Susan, Djouder, Nabil, Yates, 3rd, John R, Logan, Susan K

“…Unconventional prefoldin RPB5 Interactor (URI) was identified as a transcriptional repressor that binds RNA polymerase II (pol II) through interaction with the…”
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Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence by Bainor, Anthony J, Deng, Fang-Ming, Wang, Yu, Lee, Peng, Cantor, David J, Logan, Susan K, David, Gregory

“…Distinguishing between indolent and aggressive prostate adenocarcinoma remains a priority to accurately identify patients who need therapeutic intervention…”
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UXT is required for spermatogenesis in mice by Schafler, Eric D, Thomas, Phillip A, Ha, Susan, Wang, Yu, Bermudez-Hernandez, Keria, Tang, Zuojian, Fenyö, David, Vigodner, Margarita, Logan, Susan K

“…Male mammals must simultaneously produce prodigious numbers of sperm and maintain an adequate reserve of stem cells to ensure continuous production of gametes…”
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PIM1 phosphorylation of the androgen receptor and 14-3-3 ζ regulates gene transcription in prostate cancer by Ruff, Sophie E., Vasilyev, Nikita, Nudler, Evgeny, Logan, Susan K., Garabedian, Michael J.

“…PIM1 is a serine/threonine kinase over-expressed in prostate cancer. We have previously shown that PIM1 phosphorylates the androgen receptor (AR), the primary…”
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A genome-wide RNA interference screen identifies new regulators of androgen receptor function in prostate cancer cells by Imberg-Kazdan, Keren, Ha, Susan, Greenfield, Alex, Poultney, Christopher S, Bonneau, Richard, Logan, Susan K, Garabedian, Michael J

“…The androgen receptor (AR) is a mediator of both androgen-dependent and castration-resistant prostate cancers. Identification of cellular factors affecting AR…”
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Unbiased proteomic mapping of the LINE-1 promoter using CRISPR Cas9 by Briggs, Erica M, Mita, Paolo, Sun, Xiaoji, Ha, Susan, Vasilyev, Nikita, Leopold, Zev R, Nudler, Evgeny, Boeke, Jef D, Logan, Susan K

“…The autonomous retroelement Long Interspersed Element-1 (LINE-1) mobilizes though a copy and paste mechanism using an RNA intermediate (retrotransposition)…”
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A re-evaluation of LINE-1 ORF2 expression in LNCaP prostate cancer cells by Briggs, Erica M, Spadafora, Corrado, Logan, Susan K

“…We previously examined expression of Long Interspersed Element-1 (LINE-1) in a variety of prostate cancer cells including hormone-dependent LNCaP cells. These…”
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Long interspersed nuclear element-1 expression and retrotransposition in prostate cancer cells by Briggs, Erica M, Ha, Susan, Mita, Paolo, Brittingham, Gregory, Sciamanna, Ilaria, Spadafora, Corrado, Logan, Susan K

“…Long Interspersed Nuclear Element-1 (LINE-1) is an autonomous retrotransposon that generates new genomic insertions through the retrotransposition of a RNA…”
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TBLR1 as an androgen receptor (AR) coactivator selectively activates AR target genes to inhibit prostate cancer growth by Daniels, Garrett, Li, Yirong, Gellert, Lan Lin, Zhou, Albert, Melamed, Jonathan, Wu, Xinyu, Zhang, Xinming, Zhang, David, Meruelo, Daniel, Logan, Susan K, Basch, Ross, Lee, Peng

“…Androgen receptor (AR), a steroid hormone receptor, is critical for prostate cancer growth. However, activation of AR by androgens can also lead to growth…”
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Identification of PIM1 substrates reveals a role for NDRG1 phosphorylation in prostate cancer cellular migration and invasion by Ledet, Russell J., Ruff, Sophie E., Wang, Yu, Nayak, Shruti, Schneider, Jeffrey A., Ueberheide, Beatrix, Logan, Susan K., Garabedian, Michael J.

“…PIM1 is a serine/threonine kinase that promotes and maintains prostate tumorigenesis. While PIM1 protein levels are elevated in prostate cancer relative to…”
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Androgen receptor levels are upregulated by Akt in prostate cancer by Ha, Susan, Ruoff, Rachel, Kahoud, Nicole, Franke, Thomas F, Logan, Susan K

“…Multiple lines of evidence suggest a functional link between the androgen receptor (AR) and the serine/threonine kinase Akt in the development and progression…”
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Revisiting the role of Wnt/β-catenin signaling in prostate cancer by Schneider, Jeffrey A., Logan, Susan K.

“…The androgen receptor (AR) is a widely accepted therapeutic target in prostate cancer and multiple studies indicate that the AR and Wnt/β-catenin pathways…”
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Regulation of Androgen Receptor-Mediated Transcription by RPB5 Binding Protein URI/RMP by Mita, Paolo, Savas, Jeffrey N., Djouder, Nabil, Yates, John R., Ha, Susan, Ruoff, Rachel, Schafler, Eric D., Nwachukwu, Jerome C., Tanese, Naoko, Cowan, Nicholas J., Zavadil, Jiri, Garabedian, Michael J., Logan, Susan K.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cell-specific Regulation of Androgen Receptor Phosphorylation in Vivo by Taneja, Samir S., Ha, Susan, Swenson, Nicole K., Huang, Hong Ying, Lee, Peng, Melamed, Jonathan, Shapiro, Ellen, Garabedian, Michael J., Logan, Susan K.

“…The biological ramifications of phosphorylation of the androgen receptor (AR) are largely unknown. To examine the phosphorylation of AR at serine 213, a…”
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