Search Results - "Logan, Paige E."
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APOE ε4 is associated with earlier symptom onset in LOAD but later symptom onset in EOAD
Published in Alzheimer's & dementia (01-05-2023)“…Background We studied the effect of apolipoprotein E (APOE) ε4 status and sex on age of symptom onset (AO) in early‐ (EO) and late‐ (LO) onset Alzheimer's…”
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Predicting the Emergence of Major Neurocognitive Disorder Within Three Months After a Stroke
Published in Frontiers in aging neuroscience (16-08-2021)“…Background: Neurocognitive disorder (NCD) is common after stroke, with major NCD appearing in about 10% of survivors of a first-ever stroke. We aimed to…”
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APOE ε4 carrier status and sex differentiate rates of cognitive decline in early‐ and late‐onset Alzheimer's disease
Published in Alzheimer's & dementia (01-05-2023)“…Background We studied the effect of apolipoprotein E (APOE) ε4 status and sex on rates of cognitive decline in early‐ (EO) and late‐ (LO) onset Alzheimer's…”
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Associations Between Social Network Characteristics and Brain Structure Among Older Adults
Published in Alzheimer's & dementia (01-02-2024)“…INTRODUCTION Social connectedness is associated with slower cognitive decline among older adults. Recent research suggests that distinct aspects of social…”
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Criterion Validation of Tau PET Staging Schemes in Relation to Cognitive Outcomes
Published in Journal of Alzheimer's disease (01-01-2023)“…Utilization of NIA-AA Research Framework requires dichotomization of tau pathology. However, due to the novelty of tau-PET imaging, there is no consensus on…”
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A simulative deep learning model of SNP interactions on chromosome 19 for predicting Alzheimer's disease risk and rates of disease progression
Published in Alzheimer's & dementia (01-12-2023)“…BACKGROUND Identifying genetic patterns that contribute to Alzheimer's disease (AD) is important not only for pre‐symptomatic risk assessment but also for…”
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APOE4 is associated with earlier symptom onset in LOAD but later symptom onset in EOAD
Published in Alzheimer's & dementia (01-12-2021)“…Background Apolipoprotein‐ε4 (APOE‐ε4) is the strongest genetic risk factor for sporadic Alzheimer’s disease (AD). APOE‐ε4 has been associated with younger…”
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Transcriptomic profiling of brain amyloidosis and Alzheimer’s disease phenotypes identifies novel gene targets from peripheral blood gene expression data
Published in Alzheimer's & dementia (01-06-2023)“…Background In an effort towards pre‐symptomatic risk assessment, precision medicine and biomarker development in AD, we evaluated the efficacy of…”
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Females Derive Greater Neuroprotective Benefits from Social Connectedness than Males
Published in Alzheimer's & dementia (01-12-2023)“…Background Social connectedness is associated with better cognitive performance among older adults. Previously, we found that bridging (access to an expansive…”
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Females Derive Greater Neuroprotective Benefits from Social Connectedness than Males
Published in Alzheimer's & dementia (01-12-2023)“…Background Social connectedness is associated with better cognitive performance among older adults. Previously, we found that bridging (access to an expansive…”
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Increased Bridging Characteristics in Social Networks are Associated with Increasing Amygdala Volume and Grey Matter Density
Published in Alzheimer's & dementia (01-12-2022)“…Background Social connectedness has been linked to decreased rates of cognitive decline particularly among older adults (Fratiglioni et al., 2004). Several…”
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Early‐onset APOE‐ε4 carriers show greater decline in memory, language and executive function than late‐onset carriers
Published in Alzheimer's & dementia (01-12-2021)“…Background Apolipoprotein‐ε4 (APOE‐ε4) is the strongest genetic risk factor for sporadic Alzheimer’s disease (AD). However, whether APOE‐ε4 accelerates…”
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FDG-PET Brain Metabolic Changes in A-/T-/N-Early- and Late-onset Cognitively Impaired Subjects (1871)
Published in Neurology (13-04-2021)“…Abstract only…”
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Abstract P66: Prediction of Early Post-Stroke Major Neurocognitive Disorder Using Support Vector Machines
Published in Stroke (1970) (01-03-2021)“…Neurocognitive disorder (NCD) appears in 10% of survivors of a first-ever stroke and in 30% after a recurrent one. We aimed to classify clinical- and imaging…”
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Increased Bridging Characteristics in Social Networks are Associated with Increasing Amygdala Volume and Grey Matter Density
Published in Alzheimer's & dementia (01-12-2022)“…Background Social connectedness has been linked to decreased rates of cognitive decline particularly among older adults (Fratiglioni et al., 2004). Several…”
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Sex‐associated differences in plasma and cerebrospinal fluid biomarkers in Early‐onset Alzheimer’s disease
Published in Alzheimer's & dementia (01-12-2023)“…Background Female sex is associated with greater atrophy, amyloid and tau burden in Early‐onset Alzheimer’s Disease (EOAD) in the Longitudinal EOAD Study…”
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Associations of plasma GFAP, NfL, and p‐tau231 with early‐onset Alzheimer’s Disease pathology
Published in Alzheimer's & dementia (01-12-2023)“…Background Increased levels of glial fibrillary acidic protein (GFAP), neurofilament light (NfL), and phosphorylated tau 231 (p‐tau231) in plasma have been…”
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Associations of plasma GFAP, NfL, and p‐tau231 with early‐onset Alzheimer’s Disease pathology
Published in Alzheimer's & dementia (01-12-2023)“…Background Increased levels of glial fibrillary acidic protein (GFAP), neurofilament light (NfL), and phosphorylated tau 231 (p‐tau231) in plasma have been…”
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Associations of GFAP, NfL, Aβ42/40, and pTau231 with global cognition in LEADS
Published in Alzheimer's & dementia (01-12-2023)“…Background Historically, Alzheimer’s disease (AD) biomarkers have been used to identify the presence of pathology and have been shown to change well ahead of…”
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Sex‐associated differences in plasma and cerebrospinal fluid biomarkers in Early‐onset Alzheimer’s disease
Published in Alzheimer's & dementia (01-12-2023)“…Background Female sex is associated with greater atrophy, amyloid and tau burden in Early‐onset Alzheimer’s Disease (EOAD) in the Longitudinal EOAD Study…”
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