Search Results - "Loftus, Neil"
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Global metabolic profiling of animal and human tissues via UPLC-MS
Published in Nature protocols (01-01-2013)“…Obtaining comprehensive, untargeted metabolic profiles for complex solid samples, e.g., animal tissues, requires sample preparation and access to…”
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Journal Article -
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Use of Machine Learning in Interactive Cybersecurity and Network Education
Published in Sensors (Basel, Switzerland) (09-03-2023)“…Cybersecurity is a complex subject for students to pursue. Hands-on online learning through labs and simulations can help students become more familiar with…”
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Unraveling Cecal Alterations in Clostridioides difficile Colonized Mice through Comprehensive Metabolic Profiling
Published in Journal of proteome research (31-10-2024)“…The disruption of gut microbiota caused by antibiotics favors the intestinal colonization of - a Gram-positive, spore-forming anaerobic bacterium that causes…”
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Fully automated sample preparation procedure to measure drugs of abuse in plasma by liquid chromatography tandem mass spectrometry
Published in Analytical and bioanalytical chemistry (01-08-2018)“…For the analysis of drugs and pharmaceutical compounds in biological matrices, extraction procedures are typically used for LC-MS/MS analysis often requiring…”
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Proteomics Challenges for the Assessment of Synuclein Proteoforms as Clinical Biomarkers in Parkinson's Disease
Published in Frontiers in aging neuroscience (31-03-2022)“…Parkinson's disease is a complex neurodegenerative disorder resulting in a multifaceted clinical presentation which includes bradykinesia combined with either…”
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Metabolic Phenotyping Study of Mouse Brain Following Microbiome Disruption by C. difficile Colonization
Published in Metabolites (28-10-2022)“…Clostridioides difficile infection (CDI) is responsible for an increasing number of cases of post-antibiotic diarrhea worldwide, which has high severity and…”
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Metabolic consequences for mice lacking Endosialin: LC–MS/MS-based metabolic phenotyping of serum from C56Bl/6J Control and CD248 knock‐out mice
Published in Metabolomics (01-02-2021)“…Introduction The Endosialin/CD248/TEM1 protein is expressed in adipose tissue and its expression increases with obesity. Recently, genetic deletion of CD248…”
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Global Metabolite Profiling of Human Colorectal Cancer Xenografts in Mice Using HPLC–MS/MS
Published in Journal of proteome research (07-06-2013)“…Reversed-phase gradient LC–MS was used to perform untargeted metabonomic analysis on extracts of human colorectal cancer (CRC) cell lines (COLO 205, HT-29, HCT…”
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Endogenous and xenobiotic metabolite profiling of liver extracts from SCID and chimeric humanized mice following repeated oral administration of troglitazone
Published in Xenobiotica (01-02-2014)“…Abstract 1. Metabonomic analysis, via a combination of untargeted and targeted liquid chromatography-mass spectrometry (LC-MS) and untargeted 1H NMR…”
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Metabolic Phenotyping Study of Mouse Brains Following Acute or Chronic Exposures to Ethanol
Published in Journal of proteome research (02-10-2020)“…The chronic and acute effect of ethanol administration on the metabolic phenotype of mouse brain was studied in a C57BL/6 mouse model of ethanol abuse using…”
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A Feasibility Study of Real-Time Image Processing Techniques for Small Flying Object Detection in Drones
Published in 2024 IEEE International Conference on Consumer Electronics (ICCE) (06-01-2024)“…Drone usage is increasing significantly in our daily life, from military to delivery purposes. Although drones are also used to detect objects by using…”
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Conference Proceeding -
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Metabonomic Investigation of Liver Profiles of Nonpolar Metabolites Obtained from Alcohol-Dosed Rats and Mice Using High Mass Accuracy MSn Analysis
Published in Journal of proteome research (04-02-2011)“…Alcoholism is a complex disorder that, in man, appears to be genetically influenced, although the underlying genes and molecular pathways are not completely…”
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Metabolic Phenotyping Study of Mouse Brain Following Microbiome Disruption by C.difficile Colonization
Published in Metabolites (28-10-2022)Get full text
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Metabolic Phenotyping Study of Mouse Brain Following Microbiome Disruption by IC. difficile/I Colonization
Published in Metabolites (01-10-2022)“…Clostridioides difficile infection (CDI) is responsible for an increasing number of cases of post-antibiotic diarrhea worldwide, which has high severity and…”
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Journal Article -
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Imaging mass spectrometry using chemical inkjet printing reveals differential protein expression in human oral squamous cell carcinoma
Published in Analyst (London) (01-02-2009)“…Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a recently developed technique that generates molecular profiles usually…”
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Profiling and biomarker identification in plasma from different Zucker rat strains via high mass accuracy multistage mass spectrometric analysis using liquid chromatography/mass spectrometry with a quadrupole ion trap-time of flight mass spectrometer
Published in Rapid communications in mass spectrometry (30-08-2008)“…High mass accuracy electrospray ionisation multistage tandem mass spectrometry (MSn) was applied to metabolite profiling studies on plasma samples derived from…”
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The Cybersecurity Packet Control Simulator: CSPCS
Published in 2022 IEEE Global Humanitarian Technology Conference (GHTC) (08-09-2022)“…Games have been used as a learning tool for centuries. Through game-based learning, students actively learn and practice the right way to do things. A project…”
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Conference Proceeding -
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Space Exploration Museum with Virtual Reality
Published in 2024 IEEE Integrated STEM Education Conference (ISEC) (09-03-2024)“…This research paper documents the development and ongoing testing of a Virtual Reality (VR) modern museum experience for people of all ages, especially those…”
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Conference Proceeding -
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Implementation of Second Earthwire on L6 400 kV Transmission Line
Published in 2022 57th International Universities Power Engineering Conference (UPEC) (30-08-2022)“…The Earthwire is an important device to shield the transmission line from lightnings and to exchange information among the substations. OPGWs (Optical ground…”
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Conference Proceeding