Search Results - "Loftus, Neil"

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  1. 1

    Global metabolic profiling of animal and human tissues via UPLC-MS by Want, Elizabeth J, Masson, Perrine, Michopoulos, Filippos, Wilson, Ian D, Theodoridis, Georgios, Plumb, Robert S, Shockcor, John, Loftus, Neil, Holmes, Elaine, Nicholson, Jeremy K

    Published in Nature protocols (01-01-2013)
    “…Obtaining comprehensive, untargeted metabolic profiles for complex solid samples, e.g., animal tissues, requires sample preparation and access to…”
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    Journal Article
  2. 2

    Use of Machine Learning in Interactive Cybersecurity and Network Education by Loftus, Neil, Narman, Husnu S

    Published in Sensors (Basel, Switzerland) (09-03-2023)
    “…Cybersecurity is a complex subject for students to pursue. Hands-on online learning through labs and simulations can help students become more familiar with…”
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    Journal Article
  3. 3

    Unraveling Cecal Alterations in Clostridioides difficile Colonized Mice through Comprehensive Metabolic Profiling by Deda, Olga, Armitage, Emily G, Mouskeftara, Thomai, Kachrimanidou, Melina, Zervos, Ioannis, Malousi, Andigoni, Loftus, Neil J, Taitzoglou, Ioannis, Gika, Helen

    Published in Journal of proteome research (31-10-2024)
    “…The disruption of gut microbiota caused by antibiotics favors the intestinal colonization of - a Gram-positive, spore-forming anaerobic bacterium that causes…”
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    Journal Article
  4. 4

    Fully automated sample preparation procedure to measure drugs of abuse in plasma by liquid chromatography tandem mass spectrometry by Robin, Tiphaine, Barnes, Alan, Dulaurent, Sylvain, Loftus, Neil, Baumgarten, Sigrid, Moreau, Stéphane, Marquet, Pierre, El Balkhi, Souleiman, Saint-Marcoux, Franck

    Published in Analytical and bioanalytical chemistry (01-08-2018)
    “…For the analysis of drugs and pharmaceutical compounds in biological matrices, extraction procedures are typically used for LC-MS/MS analysis often requiring…”
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    Journal Article
  5. 5

    Proteomics Challenges for the Assessment of Synuclein Proteoforms as Clinical Biomarkers in Parkinson's Disease by Pons, Marie-Laure, Loftus, Neil, Vialaret, Jerome, Moreau, Stephane, Lehmann, Sylvain, Hirtz, Christophe

    Published in Frontiers in aging neuroscience (31-03-2022)
    “…Parkinson's disease is a complex neurodegenerative disorder resulting in a multifaceted clinical presentation which includes bradykinesia combined with either…”
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    Journal Article
  6. 6

    Metabolic Phenotyping Study of Mouse Brain Following Microbiome Disruption by C. difficile Colonization by Deda, Olga, Kachrimanidou, Melina, Armitage, Emily G., Mouskeftara, Thomai, Loftus, Neil J., Zervos, Ioannis, Taitzoglou, Ioannis, Gika, Helen

    Published in Metabolites (28-10-2022)
    “…Clostridioides difficile infection (CDI) is responsible for an increasing number of cases of post-antibiotic diarrhea worldwide, which has high severity and…”
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    Journal Article
  7. 7

    Metabolic consequences for mice lacking Endosialin: LC–MS/MS-based metabolic phenotyping of serum from C56Bl/6J Control and CD248 knock‐out mice by Armitage, Emily G., Barnes, Alan, Patrick, Kieran, Bechar, Janak, Harrison, Matthew J., Lavery, Gareth G., Rainger, G. Ed, Buckley, Christopher D., Loftus, Neil J., Wilson, Ian D., Naylor, Amy J.

    Published in Metabolomics (01-02-2021)
    “…Introduction The Endosialin/CD248/TEM1 protein is expressed in adipose tissue and its expression increases with obesity. Recently, genetic deletion of CD248…”
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    Journal Article
  8. 8

    Global Metabolite Profiling of Human Colorectal Cancer Xenografts in Mice Using HPLC–MS/MS by Loftus, Neil J, Lai, Lindsay, Wilkinson, Robert W, Odedra, Rajesh, Wilson, Ian D, Barnes, Alan J

    Published in Journal of proteome research (07-06-2013)
    “…Reversed-phase gradient LC–MS was used to perform untargeted metabonomic analysis on extracts of human colorectal cancer (CRC) cell lines (COLO 205, HT-29, HCT…”
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    Journal Article
  9. 9

    Endogenous and xenobiotic metabolite profiling of liver extracts from SCID and chimeric humanized mice following repeated oral administration of troglitazone by Barnes, Alan J., Baker, David R., Hobby, Kirsten, Ashton, Simon, Michopoulos, Filippos, Spagou, Konstantina, Loftus, Neil J., Wilson, Ian D.

    Published in Xenobiotica (01-02-2014)
    “…Abstract 1. Metabonomic analysis, via a combination of untargeted and targeted liquid chromatography-mass spectrometry (LC-MS) and untargeted 1H NMR…”
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    Journal Article
  10. 10

    Metabolic Phenotyping Study of Mouse Brains Following Acute or Chronic Exposures to Ethanol by Deda, Olga, Virgiliou, Christina, Armitage, Emily G, Orfanidis, Amvrosios, Taitzoglou, Ioannis, Wilson, Ian D, Loftus, Neil, Gika, Helen G

    Published in Journal of proteome research (02-10-2020)
    “…The chronic and acute effect of ethanol administration on the metabolic phenotype of mouse brain was studied in a C57BL/6 mouse model of ethanol abuse using…”
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    Journal Article
  11. 11

    A Feasibility Study of Real-Time Image Processing Techniques for Small Flying Object Detection in Drones by Loftus, Neil, Parlato, Cade, McGinty, Amelia, Kizilay, Furkan, Narman, Husnu S.

    “…Drone usage is increasing significantly in our daily life, from military to delivery purposes. Although drones are also used to detect objects by using…”
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    Conference Proceeding
  12. 12

    Metabonomic Investigation of Liver Profiles of Nonpolar Metabolites Obtained from Alcohol-Dosed Rats and Mice Using High Mass Accuracy MSn Analysis by Loftus, Neil, Barnes, Alan, Ashton, Simon, Michopoulos, Filippos, Theodoridis, Georgios, Wilson, Ian, Ji, Cheng, Kaplowitz, Neil

    Published in Journal of proteome research (04-02-2011)
    “…Alcoholism is a complex disorder that, in man, appears to be genetically influenced, although the underlying genes and molecular pathways are not completely…”
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    Journal Article
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    Metabolic Phenotyping Study of Mouse Brain Following Microbiome Disruption by IC. difficile/I Colonization by Deda, Olga, Kachrimanidou, Melina, Armitage, Emily G, Mouskeftara, Thomai, Loftus, Neil J, Zervos, Ioannis, Taitzoglou, Ioannis, Gika, Helen

    Published in Metabolites (01-10-2022)
    “…Clostridioides difficile infection (CDI) is responsible for an increasing number of cases of post-antibiotic diarrhea worldwide, which has high severity and…”
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    Journal Article
  15. 15

    Imaging mass spectrometry using chemical inkjet printing reveals differential protein expression in human oral squamous cell carcinoma by Patel, Soyab A, Barnes, Alan, Loftus, Neil, Martin, Rachel, Sloan, Philip, Thakker, Nalin, Goodacre, Royston

    Published in Analyst (London) (01-02-2009)
    “…Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a recently developed technique that generates molecular profiles usually…”
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    Journal Article
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    The Cybersecurity Packet Control Simulator: CSPCS by Loftus, Neil, Green, Cameron, Narman, Husnu S.

    “…Games have been used as a learning tool for centuries. Through game-based learning, students actively learn and practice the right way to do things. A project…”
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    Conference Proceeding
  19. 19

    Space Exploration Museum with Virtual Reality by Maddy, Joshua, Loftus, Neil, Vitalos, Hannah, Zerkle, Haleigh, Narman, Husnu S.

    “…This research paper documents the development and ongoing testing of a Virtual Reality (VR) modern museum experience for people of all ages, especially those…”
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    Conference Proceeding
  20. 20

    Implementation of Second Earthwire on L6 400 kV Transmission Line by Federico, Padoan, Haddad, Manu, Albano, Maurizio, Robson, Stephen, Dongsheng, Guo, Land, Christopher, Loftus, Neil

    “…The Earthwire is an important device to shield the transmission line from lightnings and to exchange information among the substations. OPGWs (Optical ground…”
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    Conference Proceeding