Search Results - "Lofthouse, Shari A."

The ovine nasal mucosa: An alternative tissue site for mucosal immunization by Sedgmen, Bradley J., Lofthouse, Shari A., Meeusen, Els N.T.

“…The ovine nasal mucosal environment has histological and ultrastructural features that resemble well-known inductive sites of mucosa-associated lymphoid…”
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Alternative routes of mucosal immunization in large animals by Sedgmen, Bradley J, Meeusen, Els N T, Lofthouse, Shari A

“…Mucosal immunization regimes that employ the oral route of delivery are often compromised by antigen degradation in the stomach. Moreover, tolerance or…”
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Peptide mimics of a tumor antigen induce functional cytotoxic T cells by Apostolopoulos, Vasso, Lofthouse, Shari A, Popovski, Violeta, Chelvanayagam, Gareth, Sandrin, Mauro S, McKenzie, lan F.C

“…The ability to mimic peptide/peptide and/or peptide/carbohydrate structures may be important in generating cross-reactive antibodies for autoimmune and other…”
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Optimization of an ovine antibody-secreting cell assay for detection of antigen-specific immunoglobulin production in peripheral blood leukocytes by Sedgmen, Bradley J, Lofthouse, Shari A, Meeusen, Els NT

“…Enumeration of antibody‐secreting cells in peripheral blood by enzyme‐linked immunospot (ELISPOT) has been used in human studies to detect antigen‐specific…”
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Antibody isotype profiles in serum and circulating antibody-secreting cells following mucosal and peripheral immunisations of sheep by Premier, Robert R, Jacobs, Helen J, Lofthouse, Shari A, Sedgmen, Bradley J, Meeusen, Els N.T

“…The isotype-specific antibody responses of sheep immunised with keyhole limpet hemocyanin by a peripheral route (intramuscular (IM) injection) were compared to…”
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Cellular and molecular characterisation of the ovine rectal mucosal environment by Sedgmen, Bradley J., Lofthouse, Shari A., Scheerlinck, Jean-Pierre Y., Meeusen, Els N.T.

“…Immunohistological characterisation of ovine rectal tissue has revealed the presence of lymphoid follicles, predominantly in the submucosa, that closely…”
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In vitro testing of a pulsatile delivery system and its in vivo application for immunisation against tetanus toxoid by Cardamone, Michael, Lofthouse, Shari A, Lucas, Jane C, Lee, Rogan P, O'Donoghue, Michael, Brandon, Mal R

“…Problems such as patient compliance and overdosing call for the development of pulsatile drug delivery devices. The in vitro and in vivo testing of a pulsatile…”
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Sustained-release delivery systems and their application for endoparasite control in animals by Cardamone, Michael, Lee, Rogan P, Lucas, Jane C, Birks, Duncan V.A, O'Donoghue, Michael, Lofthouse, Shari A, Brandon, Mal R

“…A solid formulation of a potent anthelmintic macrocyclic lactone, moxidectin, was administered using a non-degradable delivery device to discharge the agent…”
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Induction of T 1 (cytotoxic lymphocyte) and/or T 2 (antibody) responses to a mucin-1 tumour antigen by Lofthouse, Shari A., Apostolopoulos, Vasso, Pietersz, Geoffrey A., Li, Wenjun, McKenzie, Ian F.C.

“…Effective vaccination-based control of intracellular pathogens or parasites and various tumours is dependent upon induction of cytotoxic lymphocytes and other…”
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Induction of T1 (cytotoxic lymphocyte) and/or T2 (antibody) responses to a mucin-1 tumour antigen by LOFTHOUSE, S. A, APOSTOLOPOULOS, V, PIETERSZ, G. A, LI, W, MCKENZIE, I. F. C

“…Effective vaccination-based control of intracellular pathogens or parasites and various tumours is dependent upon induction of cytotoxic lymphocytes and other…”
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Parameters related to the application of recombinant ovine interleukin-1β as an adjuvant by Lofthouse, Shari A., Andrews, Arna E., Barcham, Garry J., Nash, Andrew D.

“…This paper describes aspects of the safety and efficacy of recombinant ovine interleukin-1β (rovIL-1β) as an immunological adjuvant. A dose-response…”
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