Search Results - "Loes I. Segerink"

Point-of-care CRISPR/Cas nucleic acid detection: Recent advances, challenges and opportunities by van Dongen, Jeanne E., Berendsen, Johanna T.W., Steenbergen, Renske D.M., Wolthuis, Rob M.F., Eijkel, Jan C.T., Segerink, Loes I.

“…With the trend of moving molecular tests from clinical laboratories to on-site testing, there is a need for nucleic acid based diagnostic tools combining the…”
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Innovative electrode and chip designs for transendothelial electrical resistance measurements in organs-on-chips by Holzreuter, Muriel A, Segerink, Loes I

“…Many different epithelial and endothelial barriers in the human body ensure the proper functioning of our organs by controlling which substances can pass from…”
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Direct quantification of transendothelial electrical resistance in organs-on-chips by van der Helm, Marinke W., Odijk, Mathieu, Frimat, Jean-Philippe, van der Meer, Andries D., Eijkel, Jan C.T., van den Berg, Albert, Segerink, Loes I.

“…Measuring transendothelial or transepithelial electrical resistance (TEER) is a widely used method to monitor cellular barrier tightness in organs-on-chips…”
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Measuring direct current trans-epithelial electrical resistance in organ-on-a-chip microsystems by Odijk, Mathieu, van der Meer, Andries D, Levner, Daniel, Kim, Hyun Jung, van der Helm, Marinke W, Segerink, Loes I, Frimat, Jean-Phillipe, Hamilton, Geraldine A, Ingber, Donald E, van den Berg, Albert

“…Trans-epithelial electrical resistance (TEER) measurements are widely used as real-time, non-destructive, and label-free measurements of epithelial and…”
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Microfluidic organ-on-chip technology for blood-brain barrier research by van der Helm, Marinke W, van der Meer, Andries D, Eijkel, Jan C T, van den Berg, Albert, Segerink, Loes I

“…Organs-on-chips are a new class of microengineered laboratory models that combine several of the advantages of current in vivo and in vitro models. In this…”
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Point-of-care vertical flow allergen microarray assay: proof of concept by Chinnasamy, Thiruppathiraja, Segerink, Loes I, Nystrand, Mats, Gantelius, Jesper, Andersson Svahn, Helene

“…Sophisticated equipment, lengthy protocols, and skilled operators are required to perform protein microarray-based affinity assays. Consequently, novel tools…”
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Contractility analysis of human engineered 3D heart tissues by an automatic tracking technique using a standalone application by Rivera-Arbeláez, José M, Cofiño-Fabres, Carla, Schwach, Verena, Boonen, Tom, Ten Den, Simone A, Vermeul, Kim, van den Berg, Albert, Segerink, Loes I, Ribeiro, Marcelo C, Passier, Robert

“…The use of Engineered Heart Tissues (EHT) as in vitro model for disease modeling and drug screening has increased, as they provide important insight into the…”
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Spermometer: electrical characterization of single boar sperm motility by de Wagenaar, Bjorn, Ph.D, Geijs, Daan J., B.Sc, de Boer, Hans, Bomer, Johan G., B.Eng, Olthuis, Wouter, Ph.D, van den Berg, Albert, Ph.D, Segerink, Loes I., Ph.D

“…Objective To study single sperm boar motility using electrical impedance measurements in a microfluidic system. Design Comparison of the optical data and…”
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Comparative Analysis of Urine Fractions for Optimal Bladder Cancer Detection Using DNA Methylation Markers by Hentschel, Anouk E, Nieuwenhuijzen, Jakko A, Bosschieter, Judith, Splunter, Annina P van, Lissenberg-Witte, Birgit I, Voorn, J Patrick van der, Segerink, Loes I, Moorselaar, R Jeroen A van, Steenbergen, Renske D M

“…DNA methylation analysis of full void urine and urine pellet seems promising for bladder cancer (BC) detection and surveillance. Urinary cell-free DNA from…”
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Label-free, high-throughput, electrical detection of cells in droplets by Kemna, Evelien W M, Segerink, Loes I, Wolbers, Floor, Vermes, István, van den Berg, Albert

“…Today, droplet based microfluidics has become a standard platform for high-throughput single cell experimentation and analysis. However, until now no…”
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Label-Free Microfluidic Impedance Cytometry for Acrosome Integrity Assessment of Boar Spermatozoa by Kruit, Stella A, de Bruijn, Douwe S, Broekhuijse, Marleen L. W. J, Olthuis, Wouter, Segerink, Loes I

“…Microfluidics and lab-on-chip technologies have been used in a wide range of biomedical applications. They are known as versatile, rapid, and low-cost…”
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‘Feeling Hot’: Exploring the feasibility of nocturnal erection detection through penile temperature measurements by Torenvlied, Hille J., Trip, Evelien, Olthuis, Wouter, Segerink, Loes I., Pelger, Rob C. M., Beck, Jack J. H.

“…Objectives The observational ‘Feeling Hot’ study aims to evaluate the feasibility of employing overnight penile temperature measurements for the detection of…”
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‘Staying Hot’: Investigating the influence of overnight conditions on the penile skin temperature during male sexual arousal—A novel methodology for nocturnal erection detection by Torenvlied, Hille J., Trip, Evelien, Olthuis, Wouter, Segerink, Loes I., Beck, Jack J. H.

“…Objective The objective of this study is to assess the impact of overnight environmental conditions on erectile penile temperature within a controlled setting,…”
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On-chip determination of spermatozoa concentration using electrical impedance measurements by Segerink, Loes I, Sprenkels, Ad J, ter Braak, Paul M, Vermes, Istvan, van den Berg, Albert

“…In this article we describe the development of a microfluidic chip to determine the concentration of spermatozoa in semen, which is a main quality parameter…”
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Systematic characterization of cleanroom-free fabricated macrovalves, demonstrating pumps and mixers for automated fluid handling tuned for organ-on-chip applications by Bossink, Elsbeth G. B. M., Vollertsen, Anke R., Loessberg-Zahl, Joshua T., van der Meer, Andries D., Segerink, Loes I., Odijk, Mathieu

“…Integrated valves enable automated control in microfluidic systems, as they can be applied for mixing, pumping and compartmentalization purposes. Such…”
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Automated assessment of human engineered heart tissues using deep learning and template matching for segmentation and tracking by Rivera‐Arbeláez, José M., Keekstra, Danjel, Cofiño‐Fabres, Carla, Boonen, Tom, Dostanic, Milica, Den, Simone A., Vermeul, Kim, Mastrangeli, Massimo, Berg, Albert, Segerink, Loes I., Ribeiro, Marcelo C., Strisciuglio, Nicola, Passier, Robert

“…The high rate of drug withdrawal from the market due to cardiovascular toxicity or lack of efficacy, the economic burden, and extremely long time before a…”
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Bottom-Up Assembled Photonic Crystals for Structure-Enabled Label-Free Sensing by Wang, Juan, Pinkse, Pepijn W. H, Segerink, Loes I, Eijkel, Jan C. T

“…Photonic crystals (PhCs) display photonic stop bands (PSBs) and at the edges of these PSBs transport light with reduced velocity, enabling the PhCs to confine…”
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Density Control over MBD2 Receptor-Coated Surfaces Provides Superselective Binding of Hypermethylated DNA by Kolkman, Ruben W., Michel-Souzy, Sandra, Wasserberg, Dorothee, Segerink, Loes I., Huskens, Jurriaan

“…Using the biomarker hypermethylated DNA (hmDNA) for cancer detection requires a pretreatment to isolate or concentrate hmDNA from nonmethylated DNA. Affinity…”
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Flow-Free Microfluidic Device for Quantifying Chemotaxis in Spermatozoa by Berendsen, Johanna T. W, Kruit, Stella A, Atak, Nihan, Willink, Ellen, Segerink, Loes I

“…Current male fertility diagnosis tests focus on assessing the quality of semen samples by studying the concentration, total volume, and motility of…”
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Increasing the Sensitivity of Electrochemical DNA Detection by a Micropillar-Structured Biosensing Surface by Movilli, Jacopo, Kolkman, Ruben W, Rozzi, Andrea, Corradini, Roberto, Segerink, Loes I, Huskens, Jurriaan

“…The available active surface area and the density of probes immobilized on this surface are responsible for achieving high specificity and sensitivity in…”
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