Search Results - "Loeffler, R S"

Cross-resistance to polyene and azole drugs in Cryptococcus neoformans by JOSEPH-HORNE, T, HOLLOMON, D, LOEFFLER, R. S. T, KELLY, S. L

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Amphotericin B resistant isolates of Cryptococcus neoformans without alteration in sterol biosynthesis by JOSEPH-HORNE, T, LOEFFLER, R. S. T, HOLLOMON, D. W, KELLY, S. L

“…Amphotericin B resistant mutants of Cryptococcus neoformans were isolated accumulating mainly ergosterol. Cross-resistance to azole antifungals was not…”
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RIP (repeat induced point mutation) as a tool in the analysis of P-450 and sterol biosynthesis in Neurospora crassa by Connerton, I F, Deane, S M, Butters, J A, Loeffler, R S, Hollomon, D W

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Interaction of the lacZ beta-galactosidase of Escherichia coli with some beta-D-galactopyranoside competitive inhibitors by Loeffler, R S, Sinnott, M L, Sykes, B D, Withers, S G

“…1. The location of the bivalent metal cation with respect to bound competitive inhibitors in Escherichia coli (lacZ) beta-galactosidase was investigated by…”
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Isolation and characterization of polyene-resistant mutants from the maize smut pathogen, Ustilago maydis, defective in ergosterol biosynthesis by James, C.S, Burden, R.S, Loeffler, R.S.T, Hargreaves, J.A

“…Ustilago maydis mutants resistant to polyene antibiotics were screened for defects in ergosterol biosynthesis. Slow-growing mutants recovered after selecting…”
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Altered P450 activity associated with direct selection for fungal azole resistance by Joseph-Horne, T., Hollomon, D., Loeffler, R.S.T., Kelly, S.L.

“…Azole antifungals inhibit CYP51A1-mediated sterol 14α-demethylation and the mechanism(s) of resistance to such compounds in Ustilago maydis were examined. The…”
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