Search Results - "Loeffler, R F"

SC-49518 enhances gastric emptying of solid and liquid meals and stimulates gastrointestinal motility in dogs by a 5-hydroxytryptamine4 receptor mechanism by Gullikson, G W, Virina, M A, Loeffler, R F, Yang, D C, Goldstin, B, Wang, S X, Moummi, C, Flynn, D L, Zabrowski, D L

“…SC-49518 (N-[exo-(hexahydro-1H-pyrrolizine-1-yl)methyl]-2-methoxy-4- amino-5-chlorobenzamide HCl), a new benzamide gastrointestinal prokinetic compound, was…”
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Relationship of serotonin-3 receptor antagonist activity to gastric emptying and motor-stimulating actions of prokinetic drugs in dogs by Gullikson, G W, Loeffler, R F, Viriña, M A

“…Drugs that enhance gastrointestinal motility include the benzamide drugs metoclopramide, cisapride and renzapride (BRL-24924). Because these agents also are…”
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Polymeric delivery of the active isomer of misoprostol reduces systemic availability and uterotonic activity by Gullikson, G W, Loeffler, R F, Mehrotra, D V, Casler, J J, Bianchi, R G, Schmidt, R E, Khoshaba, N, Perkins, W E

“…SC-30249 is the active isomer of misoprostol responsible for its mucosal protective effects against nonsteroidal anti-inflammatory drugs (NSAIDS). Linkage of…”
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Effects of auranofin and myochrysine on intestinal transport and morphology in the rat by Ammon, H V, Fowle, S A, Cunningham, J A, Komorowski, R A, Loeffler, R F

“…Auranofin (SKF-D 39162) is an oral gold preparation for the treatment of rheumatoid arthritis. One of its major side effects is diarrhoea. To determine one…”
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Effects of sulfodeoxycholate on rat and rabbit small intestine by Ammon, H V, Tapper, E J, Komorowski, R A, Charaf, U K, Loeffler, R F, Lewand, D, Walter, L G

“…To determine how sulfation alters the biological properties of dihydroxy bile acids, we compared the effects of 3-sulfodeoxycholate (SDC) and deoxycholate (DC)…”
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Acid pH enhances the effects of taurodeoxycholate on water and solute transport in the human and rat jejunum by AMMON, H. V, AMARNANI, N. H, LOEFFLER, R. F

“…The relative rate of unspecific binding of bile acids to brush border membrane vesicles resembles their relative potencies as intestinal secretagogues. This…”
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Effects of amphotericin B and cholera toxin on intestinal transport in the rat. An in vivo model for the effects of dihydroxy bile acids and fatty acids on intestinal transport by Ammon, H V, Walter, L G, Loeffler, R F

“…In vivo perfusion experiments were performed in the rat jejunum and colon to test the hypothesis that the changes in intestinal solute transport induced by…”
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Occlusive coronary artery disease and parental history of myocardial infarction by Anderson, A J, Loeffler, R F, Barboriak, J J, Rimm, A A

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