Search Results - "Loef, Bert"
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Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial
Published in The Lancet infectious diseases (01-07-2016)“…Summary Background In critically ill patients, antibiotic therapy is of great importance but long duration of treatment is associated with the development of…”
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Conservative versus Liberal Oxygenation Targets in Intensive Care Unit Patients (ICONIC): A Randomized Clinical Trial
Published in American journal of respiratory and critical care medicine (01-10-2023)“…Supplemental oxygen is widely administered to ICU patients, but appropriate oxygenation targets remain unclear. This study aimed to determine whether a…”
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Fluid Resuscitation in Septic Patients Improves Systolic but not Diastolic Middle Cerebral Artery Flow Velocity
Published in Ultrasound in medicine & biology (01-11-2017)“…To investigate the effects of fluid resuscitation on cerebral hemodynamics in sepsis, the following set of transcranial Doppler (TCD) parameters was used:…”
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Changes in ventilator settings and ventilation–induced lung injury in burn patients—A systematic review
Published in Burns (01-06-2020)“…•There is a high variety in mechanical ventilation practices in burn patients.•A trend towards implementation of lung protective ventilation is noticeable.•It…”
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Impact of reduced antibiotic treatment duration on antimicrobial resistance in critically ill patients in the randomized controlled SAPS-trial
Published in Frontiers in medicine (02-02-2023)“…In the previously reported SAPS trial (https://clinicaltrials.gov/ct2/show/NCT01139489), procalcitonin-guidance safely reduced the duration of antibiotic…”
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The right time to measure anti-Xa activity in critical illness: pharmacokinetics of therapeutic dose nadroparin
Published in Research and practice in thrombosis and haemostasis (01-05-2023)“…Peak anti-Xa activity of low-molecular-weight heparin nadroparin is measured 3 to 5 hours after subcutaneous injection. In critically ill patients,…”
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Discomfort and factual recollection in intensive care unit patients
Published in Critical care (London, England) (01-12-2004)“…A stay in the intensive care unit (ICU), although potentially life-saving, may cause considerable discomfort to patients. However, retrospective assessment of…”
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Computer-assisted glucose control in critically ill patients
Published in Intensive care medicine (01-08-2008)“…Objective Intensive insulin therapy is associated with the risk of hypoglycemia and increased costs of material and personnel. We therefore evaluated the…”
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Incidence, treatment and mortality of new-onset atrial fibrillation patients at the intensive care unit
Published in Open heart (06-04-2020)“…ObjectiveCritically ill patients admitted to the intensive care unit (ICU) often develop atrial fibrillation (AF), with an incidence of around 5%. Stroke…”
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HEPBURN - investigating the efficacy and safety of nebulized heparin versus placebo in burn patients with inhalation trauma: study protocol for a multi-center randomized controlled trial
Published in Trials (25-03-2014)“…Pulmonary coagulopathy is a hallmark of lung injury following inhalation trauma. Locally applied heparin attenuates lung injury in animal models of smoke…”
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Implementation and evaluation of a nurse-centered computerized potassium regulation protocol in the intensive care unit--a before and after analysis
Published in BMC medical informatics and decision making (25-01-2010)“…Potassium disorders can cause major complications and must be avoided in critically ill patients. Regulation of potassium in the intensive care unit (ICU)…”
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Nebulized Heparin in Burn Patients with Inhalation Trauma-Safety and Feasibility
Published in Journal of clinical medicine (25-03-2020)“…Pulmonary hypercoagulopathy is intrinsic to inhalation trauma. Nebulized heparin could theoretically be beneficial in patients with inhalation injury, but…”
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The impact of a reduced dose of dexamethasone on glucose control after coronary artery bypass surgery
Published in Cardiovascular diabetology (17-12-2007)“…Intensive insulin therapy to maintain normoglycemia after cardiac surgery reduces morbidity and mortality. We investigated the magnitude and duration of…”
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Endotracheal suctioning versus minimally invasive airway suctioning in intubated patients: a prospective randomised controlled trial
Published in Intensive care medicine (01-03-2003)“…Endotracheal suctioning in intubated patients is routinely applied in most ICUs but may have negative side effects. We hypothesised that on-demand minimally…”
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Survival benefit of cardiopulmonary bypass support in bilateral lung transplantation for emphysema patients
Published in Transplantation (27-05-2002)“…This study is designed to examine a possible association of cardiopulmonary bypass (CPB) support and outcome of lung transplantation in a well-balanced group…”
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Patient recollection of airway suctioning in the ICU: routine versus a minimally invasive procedure
Published in Intensive care medicine (01-03-2003)“…Many patients have an unpleasant recollection of routine endotracheal suctioning after discharge from the Intensive Care Unit (ICU). We hypothesized that…”
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Systemic VEGF levels after coronary artery bypass graft surgery reflects the extent of inflammatory response
Published in Acute cardiac care (2006)“…Circulating vascular endothelial growth factor (VEGF) was studied as a substitute endpoint for treatment response after VEGF plasmid therapy. The effect of…”
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To ventilate or not after minimally invasive direct coronary artery bypass surgery: The role of epidural anesthesia
Published in Journal of cardiothoracic and vascular anesthesia (01-02-2002)“…Objective: To evaluate the effect of immediate postoperative extubation and postoperative ventilation after minimally invasive direct coronary artery bypass…”
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Endotracheal suctioning versus minimally invasive airway suctioning in intubated patients: a prospective randomised controlled trial
Published in Intensive care medicine (01-07-2003)Get full text
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20
Patient recollection of airway suctioning in the ICU: routine versus a minimally invasive procedure
Published in Intensive care medicine (01-07-2003)Get full text
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