Search Results - "Loechler, E.L."

Evidence from in vitro replication O[sup 6]-methylguanine can adopt multiple conformations by Dosanjh, M.K., Singer, B., Loechler, E.L.

“…The effect of O[sup 6]-methylguanine (m[sup 6]G) on replication, in a partially double-stranded defined 25-base oligonucleotide, has been studied under…”
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Mapping the binding site of aflatoxin B1 in DNA: systematic analysis of the reactivity of aflatoxin B1 with guanines in different DNA sequences by Benasutti, Matt, Ejadi, Samuel, Whitlow, Marc D, Loechler, Edward L

“…The mutagenic and carcinogenic chemical aflatoxin B1 (AFB1) reacts almost exclusively at the N(7)-position of guanine following activation to its reactive…”
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Molecular modeling in mutagenesis and carcinogenesis by Loechler, E L

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Construction of Escherichia coli vectors containing deoxyadenosine and deoxyguanosine adducts from (+)-anti-dibenz[a,j]anthracene diol epoxide at a defined site by Gill, Rosalynn D, Min, Zhao, Cortez, Cecilia, Harvey, Ronald G, Loechler, Edward L, DiGiovanni, John

“…Dibenz[a,j]anthracene (DB[a,j]A) is a carcinogenic polycylic aromatic hydrocarbon, which is metabolically activated through the formation of bay region diol…”
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Construction of an Escherichia coli vector containing the major DNA adduct of activated benzo[a]pyrene at a defined site by Benasutti, Matt, Ezzedine, Z. Diala, Loechler, Edward L

“…The mutagenic and carcinogenic substance benzo[a]pyrene reacts with DNA following activation to its corresponding 7,8-diol 9,10-epoxide (BPDE), and the major…”
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