Search Results - "Loechel, F"

Merosin and Laminin in Myogenesis; Specific Requirement for Merosin in Myotube Stability and Survival by Vachon, Pierre H., Loechel, Frosty, Xu, Hong, Wewer, Ulla M., Engvall, Eva

“…Laminin (laminin-1; α1-β1-γ1) is known to promote myoblast proliferation, fusion, and myotube formation. Merosin (laminin-2 and -4; α2-β1/β2-γ1) is the…”
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Merosin-deficient congenital muscular dystrophy. Partial genetic correction in two mouse models by Kuang, W, Xu, H, Vachon, P H, Liu, L, Loechel, F, Wewer, U M, Engvall, E

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A carcinoembryonic antigen polynucleotide vaccine for human clinical use by Conry, R M, LoBuglio, A F, Loechel, F, Moore, S E, Sumerel, L A, Barlow, D L, Pike, J, Curiel, D T

“…We have constructed a plasmid DNA encoding the full-length complementary DNA for human carcinoembryonic antigen (CEA) under transcriptional regulatory control…”
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Immunization with a plasmid expressing pneumococcal surface protein A (PsPa) can elicit protection against fatal infection with Streptococcus pneumoniae by MCDANIEL, L. S, LOECHEL, F, BENEDICT, C, GREENWAY, T, BRILES, D. E, CONRY, R. M, CURIEL, D. T

“…Pneumococcal surface protein A (PspA) is a protectioneliciting protein of Streptococcus pneumoniae. We observed that immunization of BALB/c mice with a plasmid…”
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ADAM 12-S Cleaves IGFBP-3 and IGFBP-5 and Is Inhibited by TIMP-3 by Loechel, Frosty, Fox, Jay W., Murphy, Gillian, Albrechtsen, Reidar, Wewer, Ulla M.

“…ADAMs are a family of multidomain proteins having proteolytic and cell adhesion activities. We have previously shown that ADAM 12-S, the secreted soluble form…”
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Non-anti-coagulant heparins: a promising approach for prevention of tumor metastasis (review) by Kragh, Michael, Loechel, Frosty

“…The metastatic spread of solid tumors is responsible for most cancer-related deaths, and unfortunately no specific anti-metastatic therapy exists. Heparin is…”
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Deep learning on chaos game representation for proteins by Löchel, Hannah F, Eger, Dominic, Sperlea, Theodor, Heider, Dominik

“…Abstract Motivation Classification of protein sequences is one big task in bioinformatics and has many applications. Different machine learning methods exist…”
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Extrasynaptic location of laminin beta 2 chain in developing and adult human skeletal muscle by Wewer, UM, Thornell, LE, Loechel, F, Zhang, X, Durkin, ME, Amano, S, Burgeson, RE, Engvall, E, Albrechtsen, R, Virtanen, I

“…We have investigated the distribution of the laminin beta 2 chain (previously s-laminin) in human fetal and adult skeletal muscle and compared it to the…”
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Fractal construction of constrained code words for DNA storage systems by Löchel, Hannah F, Welzel, Marius, Hattab, Georges, Hauschild, Anne-Christin, Heider, Dominik

“…Abstract The use of complex biological molecules to solve computational problems is an emerging field at the interface between biology and computer science…”
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Merosin-deficient congenital muscular dystrophy. Partial genetic correction in two mouse models by Kuang, W, Xu, H, Vachon, P H, Liu, L, Loechel, F, Wewer, U M, Engvall, E

“…Humans and mice with deficiency of the alpha2 subunit of the basement membrane protein laminin-2/merosin suffer from merosin-deficient congenital muscular…”
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ADAM 12, a Disintegrin Metalloprotease, Interacts with Insulin-like Growth Factor-binding Protein-3 by Shi, Zengdun, Xu, Wenzhong, Loechel, Frosty, Wewer, Ulla M., Murphy, Liam J.

“…Insulin-like growth factor-binding protein (IGFBP)-3 binds the insulin-like growth factors with high affinity and modulates their actions. Proteolytic cleavage…”
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A Novel, Secreted Form of Human ADAM 12 (Meltrin α) Provokes Myogenesis in Vivo by Gilpin, Brent J., Loechel, Frosty, Mattei, Marie-Geneviève, Engvall, Eva, Albrechtsen, Reidar, Wewer, Ulla M.

“…The ADAM (A DisintegrinAnd Metalloprotease) family of cell-surface proteins may have an important role in cellular interactions and in modulating cellular…”
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Cysteine-Rich Domain of Human ADAM 12 (Meltrin α) Supports Tumor Cell Adhesion by Iba, Kousuke, Albrechtsen, Reidar, Gilpin, Brent J., Loechel, Frosty, Wewer, Ulla M.

“…The ADAMs (A disintegrin and metalloprotease) comprise a family of membrane-anchored cell surface proteins with a putative role in cell-cell and/or cell-matrix…”
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DNA-Aeon provides flexible arithmetic coding for constraint adherence and error correction in DNA storage by Welzel, Marius, Schwarz, Peter Michael, Löchel, Hannah F., Kabdullayeva, Tolganay, Clemens, Sandra, Becker, Anke, Freisleben, Bernd, Heider, Dominik

“…The extensive information capacity of DNA, coupled with decreasing costs for DNA synthesis and sequencing, makes DNA an attractive alternative to traditional…”
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Human ADAM 12 (Meltrin α) Is an Active Metalloprotease by Loechel, F, Gilpin, B J, Engvall, E, Albrechtsen, R, Wewer, U M

“…The ADAMs ( a d isintegrin a nd m etalloprotease) are a family of multidomain proteins with structural homology to snake venom metalloproteases. We recently…”
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Regulation of human ADAM 12 protease by the prodomain. Evidence for a functional cysteine switch by Loechel, F, Overgaard, M T, Oxvig, C, Albrechtsen, R, Wewer, U M

“…The ADAMs (a disintegrin and metalloprotease) are a family of multidomain proteins that are believed to play key roles in cell-cell and cell-matrix…”
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ADAM 12 Protease Induces Adipogenesis in Transgenic Mice by Kawaguchi, Nobuko, Xu, Xiufeng, Tajima, Rie, Kronqvist, Pauliina, Sundberg, Christina, Loechel, Frosty, Albrechtsen, Reidar, Wewer, Ulla M.

“…ADAM 12 (meltrin-α) is a member of the ADAM (a disintegrin and metalloprotease) family. ADAM 12 functions as an active metalloprotease, supports cell adhesion,…”
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Comparative analyses of error handling strategies for next-generation sequencing in precision medicine by F. Löchel, Hannah, Heider, Dominik

“…Next-generation sequencing (NGS) offers the opportunity to sequence millions and billions of DNA sequences in a short period, leading to novel applications in…”
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Integrins (alpha7beta1) in muscle function and survival. Disrupted expression in merosin-deficient congenital muscular dystrophy by Vachon, P H, Xu, H, Liu, L, Loechel, F, Hayashi, Y, Arahata, K, Reed, J C, Wewer, U M, Engvall, E

“…Mutations in genes coding for dystrophin, for alpha, beta, gamma, and delta-sarcoglycans, or for the alpha2 chain of the basement membrane component merosin…”
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SCOTCH: subtype A coreceptor tropism classification in HIV-1 by Löchel, Hannah F, Riemenschneider, Mona, Frishman, Dmitrij, Heider, Dominik

“…Abstract Motivation The V3 loop of the gp120 glycoprotein of the Human Immunodeficiency Virus 1 (HIV-1) is considered to be responsible for viral coreceptor…”
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