Search Results - "Loebel, F."

Gene function in mouse embryogenesis: get set for gastrulation by Tam, Patrick P. L, Loebel, David A. F

“…During early mouse embryogenesis, temporal and spatial regulation of gene expression and cell signalling influences lineage specification, embryonic polarity,…”
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Rhou maintains the epithelial architecture and facilitates differentiation of the foregut endoderm by Loebel, David A F, Studdert, Joshua B, Power, Melinda, Radziewic, Tania, Jones, Vanessa, Coultas, Leigh, Jackson, Yvette, Rao, Renuka S, Steiner, Kirsten, Fossat, Nicolas, Robb, Lorraine, Tam, Patrick P L

“…Rhou encodes a Cdc42-related atypical Rho GTPase that influences actin organization in cultured cells. In mouse embryos at early-somite to early-organogenesis…”
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Building the mouse gastrula: signals, asymmetry and lineages by Tam, Patrick PL, Loebel, David AF, Tanaka, Satomi S

“…The mouse embryo is built by assembling the progenitors of various tissue types into a body plan. Early postimplantation development involves the establishment…”
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Timed deletion of Twist1 in the limb bud reveals age-specific impacts on autopod and zeugopod patterning by Loebel, David A F, Hor, Angelyn C C, Bildsoe, Heidi K, Tam, Patrick P L

“…Twist1 encodes a transcription factor that plays a vital role in limb development. We have used a tamoxifen-inducible Cre transgene, Ubc-CreERT2, to generate…”
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O8.02 MONITORING OF TREATMENT RESPONSE IN IDH-MUTANT GLIOMAS WITH IN-VIVO 3D MAGNETIC RESONANCE SPECTROSCOPY by Cahill, D. P., Loebel, F., Bogner, W., Marjanska, M., Gerstner, E., Batchelor, T., Rosen, B. R., Chi, A., Andronesi, O. C.

“…The hallmark metabolic alteration in mutant IDH gliomas is the production of R-2-hydroxyglutarate (2HG). 2HG can be measured in-vivo by magnetic resonance…”
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Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction by Loebel, David A F, Plageman, Jr, Timothy F, Tang, Theresa L, Jones, Vanessa J, Muccioli, Maria, Tam, Patrick P L

“…Early development of the gut endoderm and its subsequent remodeling for the formation of organ buds are accompanied by changes to epithelial cell shape and…”
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Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance by Bildsoe, Heidi, Fan, Xiaochen, Wilkie, Emilie E., Ashoti, Ator, Jones, Vanessa J., Power, Melinda, Qin, Jing, Wang, Junwen, Tam, Patrick P.L., Loebel, David A.F.

“…TWIST1, a basic helix-loop-helix transcription factor is essential for the development of cranial mesoderm and cranial neural crest-derived craniofacial…”
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Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization by Greenlees, Rebecca, Mihelec, Marija, Yousoof, Saira, Speidel, Daniel, Wu, Selwin K, Rinkwitz, Silke, Prokudin, Ivan, Perveen, Rahat, Cheng, Anson, Ma, Alan, Nash, Benjamin, Gillespie, Rachel, Loebel, David A F, Clayton-Smith, Jill, Lloyd, I Christopher, Grigg, John R, Tam, Patrick P L, Yap, Alpha S, Becker, Thomas S, Black, Graeme C M, Semina, Elena, Jamieson, Robyn V

“…Correct morphogenesis and differentiation are critical in development and maintenance of the lens, which is a classic model system for epithelial development…”
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Context-specific function of the LIM homeobox 1 transcription factor in head formation of the mouse embryo by Fossat, Nicolas, Ip, Chi Kin, Jones, Vanessa J, Studdert, Joshua B, Khoo, Poh-Lynn, Lewis, Samara L, Power, Melinda, Tourle, Karin, Loebel, David A F, Kwan, Kin Ming, Behringer, Richard R, Tam, Patrick P L

“…Lhx1 encodes a LIM homeobox transcription factor that is expressed in the primitive streak, mesoderm and anterior mesendoderm of the mouse embryo. Using a…”
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Differential response of epiblast stem cells to Nodal and Activin signalling: a paradigm of early endoderm development in the embryo by Kaufman-Francis, Keren, Goh, Hwee Ngee, Kojima, Yoji, Studdert, Joshua B., Jones, Vanessa, Power, Melinda D., Wilkie, Emilie, Teber, Erdahl, Loebel, David A. F., Tam, Patrick P. L.

“…Mouse epiblast stem cells (EpiSCs) display temporal differences in the upregulation of Mixl1 expression during the initial steps of in vitro differentiation,…”
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TWIST1 Homodimers and Heterodimers Orchestrate Lineage-Specific Differentiation by Fan, Xiaochen, Waardenberg, Ashley J., Demuth, Madeleine, Osteil, Pierre, Sun, Jane Q. J., Loebel, David A. F., Graham, Mark, Tam, Patrick P. L., Fossat, Nicolas

“…The extensive array of basic helix-loop-helix (bHLH) transcription factors and their combinations as dimers underpin the diversity of molecular function…”
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The Transcriptional and Functional Properties of Mouse Epiblast Stem Cells Resemble the Anterior Primitive Streak by Kojima, Yoji, Kaufman-Francis, Keren, Studdert, Joshua B., Steiner, Kirsten A., Power, Melinda D., Loebel, David A.F., Jones, Vanessa, Hor, Angelyn, de Alencastro, Gustavo, Logan, Grant J., Teber, Erdahl T., Tam, Oliver H., Stutz, Michael D., Alexander, Ian E., Pickett, Hilda A., Tam, Patrick P.L.

“…Mouse epiblast stem cells (EpiSCs) can be derived from a wide range of developmental stages. To characterize and compare EpiSCs with different origins, we…”
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C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47 by Fossat, Nicolas, Tourle, Karin, Radziewic, Tania, Barratt, Kristen, Liebhold, Doreen, Studdert, Joshua B, Power, Melinda, Jones, Vanessa, Loebel, David A F, Tam, Patrick P L

“…Cytidine (C) to Uridine (U) RNA editing is a post‐transcriptional modification that is accomplished by the deaminase APOBEC1 and its partnership with the…”
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Tissue interactions, cell signaling and transcriptional control in the cranial mesoderm during craniofacial development by Fan, Xiaochen, Loebel, David A F, Bildsoe, Heidi, Wilkie, Emilie E, Qin, Jing, Wang, Junwen, Tam, Patrick P L

“…Abstract The cranial neural crest and the cranial mesoderm are the source of tissues from which the bone and cartilage of the skull, face and jaws are…”
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P01.105 Clinical and imaging features of pseudoprogression in malignant glioma by Winter, S F, Vaios, E J, Muzikansky, A, Bussière, M R, Shih, H A, Martinez-Lage, M, Loebel, F, Vajkoczy, P, Dietrich, J

“…Abstract Background Pseudoprogression (PP) likely represents a unique phenomenon encountered in high-grade glioma patients within the first six months of…”
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α3 Integrin of Cell-Cell Contact Mediates Kidney Fibrosis by Integrin-Linked Kinase in Proximal Tubular E-Cadherin Deficient Mice by Zheng, Guoping, Zhang, Jianlin, Zhao, Hong, Wang, Hailong, Pang, Min, Qiao, Xi, Lee, So R, Hsu, Tzu-Ting, Tan, Thian K, Lyons, J. Guy, Zhao, Ye, Tian, Xinrui, Loebel, David A.F, Rubera, Isabella, Tauc, Michel, Wang, Ya, Wang, Yiping, Wang, Yuan M, Cao, Qi, Wang, Changqi, Lee, Vincent W.S, Alexander, Stephen I, Tam, Patrick P.L, Harris, David C.H

“…Loss of E-cadherin marks a defect in epithelial integrity and polarity during tissue injury and fibrosis. Whether loss of E-cadherin plays a causal role in…”
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Requirement for Twist1 in frontonasal and skull vault development in the mouse embryo by Bildsoe, Heidi, Loebel, David A.F., Jones, Vanessa J., Chen, You-Tzung, Behringer, Richard R., Tam, Patrick P.L.

“…Using a Cre-mediated conditional deletion approach, we have dissected the function of Twist1 in the morphogenesis of the craniofacial skeleton. Loss of Twist1…”
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The mesenchymal architecture of the cranial mesoderm of mouse embryos is disrupted by the loss of Twist1 function by Bildsoe, Heidi, Loebel, David A.F., Jones, Vanessa J., Hor, Angelyn C.C, Braithwaite, Antony W., Chen, You-Tzung, Behringer, Richard R., Tam, Patrick P.L.

“…[Display omitted] ► Loss or malformation of skull vault and base in mesoderm-specific Twist1 mutants. ► CKO cranial mesoderm loses mesenchymal properties and…”
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O8.02MONITORING OF TREATMENT RESPONSE IN IDH-MUTANT GLIOMAS WITH IN-VIVO 3D MAGNETIC RESONANCE SPECTROSCOPY by Cahill, D.P., Loebel, F., Bogner, W., Marjanska, M., Gerstner, E., Batchelor, T., Rosen, B.R., Chi, A., Andronesi, O.C.

“…The hallmark metabolic alteration in mutant IDH gliomas is the production of R-2-hydroxyglutarate (2HG). 2HG can be measured in-vivo by magnetic resonance…”
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Formation of the Embryonic Head in the Mouse: Attributes of a Gene Regulatory Network by Tam, Patrick P L, Fossat, Nicolas, Wilkie, Emilie, Loebel, David A F, Ip, Chi Kin, Ramialison, Mirana

“…The embryonic head is the first major body part to be constructed during embryogenesis. The allocation and the assembly of the progenitor tissues, which start…”
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