Search Results - "Loeb, Daniel"

The interface between hepatitis B virus capsid proteins affects self-assembly, pregenomic RNA packaging, and reverse transcription by Tan, Zhenning, Pionek, Karolyn, Unchwaniwala, Nuruddin, Maguire, Megan L, Loeb, Daniel D, Zlotnick, Adam

“…Hepatitis B virus (HBV) capsid proteins (Cps) assemble around the pregenomic RNA (pgRNA) and viral reverse transcriptase (P). pgRNA is then reverse transcribed…”
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Modulation of hepatitis B virus pregenomic RNA stability and splicing by histone deacetylase 5 enhances viral biosynthesis by Taha, Taha Y, Anirudhan, Varada, Limothai, Umaporn, Loeb, Daniel D, Petukhov, Pavel A, McLachlan, Alan, Luo, Guangxiang George, Guo, Haitao

“…Hepatitis B virus (HBV) is a worldwide health problem without curative treatments. Investigation of the regulation of HBV biosynthesis by class I and II…”
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Roles of the Envelope Proteins in the Amplification of Covalently Closed Circular DNA and Completion of Synthesis of the Plus-Strand DNA in Hepatitis B Virus by LENTZ, Thomas B, LOEB, Daniel D

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The Arginine Clusters of the Carboxy-Terminal Domain of the Core Protein of Hepatitis B Virus Make Pleiotropic Contributions to Genome Replication by LEWELLYN, Eric B, LOEB, Daniel D

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Serine phosphoacceptor sites within the core protein of hepatitis B virus contribute to genome replication pleiotropically by Lewellyn, Eric B, Loeb, Daniel D

“…The core protein of hepatitis B virus can be phosphorylated at serines 155, 162, and 170. The contribution of these serine residues to DNA synthesis was…”
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Hepatitis B Virus Polymerase Localizes to the Mitochondria, and Its Terminal Protein Domain Contains the Mitochondrial Targeting Signal by Unchwaniwala, Nuruddin, Sherer, Nathan M, Loeb, Daniel D

“…To understand subcellular sites of hepatitis B virus (HBV) replication, we visualized core (Cp), polymerase (Pol), and pregenomic RNA (pgRNA) in infected…”
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Genetically Altering the Thermodynamics and Kinetics of Hepatitis B Virus Capsid Assembly Has Profound Effects on Virus Replication in Cell Culture by Tan, Zhenning, Maguire, Megan L, Loeb, Daniel D, Zlotnick, Adam

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Full-Length Hepatitis B Virus Core Protein Packages Viral and Heterologous RNA with Similarly High Levels of Cooperativity by Porterfield, J Zachary, Dhason, Mary Savari, Loeb, Daniel D, Nassal, Michael, Stray, Stephen J, Zlotnick, Adam

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Live Cell Imaging Reveals HBV Capsid Translocation from the Nucleus To the Cytoplasm Enabled by Cell Division by Romero, Sofia, Unchwaniwala, Nuruddin, Evans, 3rd, Edward L, Eliceiri, Kevin W, Loeb, Daniel D, Sherer, Nathan M

“…Hepatitis B virus (HBV) capsid assembly is traditionally thought to occur predominantly in the cytoplasm, where the virus gains access to the virion egress…”
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Encapsidated hepatitis B virus reverse transcriptase is poised on an ordered RNA lattice by Wang, Joseph Che-Yen, Nickens, David G., Lentz, Thomas B., Loeb, Daniel D., Zlotnick, Adam

“…Assembly of a hepatitis B virus (HBV) virion begins with the formation of an RNA-filled core composed of a symmetrical capsid (built of core protein), viral…”
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Snow goose hepatitis B virus (SGHBV) envelope and capsid proteins independently contribute to the ability of SGHBV to package capsids containing single-stranded DNA in virions by Greco, Natalie, Hayes, Michael H, Loeb, Daniel D

“…Hepadnaviruses selectively package capsids containing mature double-stranded DNA (dsDNA) genomes in virions. Snow goose hepatitis B virus (SGHBV) is the only…”
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How Augmenting Reality Changes the Reality of Simulation: Ethnographic Analysis by Loeb, Daniel, Shoemaker, Jamie, Parsons, Allison, Schumacher, Daniel, Zackoff, Matthew

“…Simulation-based medical education (SBME) provides key medical training for providers to safely and ethically practice high-risk events. Augmented reality…”
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Base Pairing between cis-Acting Sequences Contributes to Template Switching during Plus-Strand DNA Synthesis in Human Hepatitis B Virus by LEWELLYN, Eric B, LOEB, Daniel D

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First-Time Use of the Seraph® 100 Microbind® Affinity Blood Filter in an Adolescent Patient with Severe COVID-19 Disease: A Case Report by Merrill, Kyle A., Krallman, Kelli A., Loeb, Daniel, Standage, Stephen W., Mattoon, Dawn, Shan, Dandan, Goldstein, Stuart L., Schuh, Meredith P.

“…The Seraph ® 100 Microbind ® Affinity Blood Filter (Seraph ® 100) is a hemoperfusion device designed to adsorb bacteria, viruses, and toxins when added to…”
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The Topology of Hepatitis B Virus Pregenomic RNA Promotes Its Replication by ABRAHAM, Teresa M, LOEB, Daniel D

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cis-Acting Sequences That Contribute to Synthesis of Minus-Strand DNA Are Not Conserved between Hepadnaviruses by MAGUIRE, Megan L, LOEB, Daniel D

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Characterization of the contribution of spliced RNAs of hepatitis B virus to DNA synthesis in transfected cultures of Huh7 and HepG2 cells by Abraham, Teresa M, Lewellyn, Eric B, Haines, Kathleen M, Loeb, Daniel D

“…Abstract Hepatitis B virus synthesizes multiple spliced RNAs that can be reverse transcribed into viral DNA. We thoroughly characterized the contribution of…”
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Base Pairing between the 5′ Half of ε and a cis-Acting Sequence, Φ, Makes a Contribution to the Synthesis of Minus-Strand DNA for Human Hepatitis B Virus by ABRAHAM, Teresa M, LOEB, Daniel D

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Development of cell cultures that express hepatitis B virus to high levels and accumulate cccDNA by Lentz, Thomas B., Loeb, Daniel D.

“…Establishment of an infection with hepatitis B virus (HBV) requires synthesis and maintenance of a covalently closed circular DNA (cccDNA) form of the viral…”
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The Sequence of the RNA Primer and the DNA Template Influence the Initiation of Plus-strand DNA Synthesis in Hepatitis B Virus by Haines, Kathleen M., Loeb, Daniel D.

“…For hepadnaviruses, the RNA primer for plus-strand DNA synthesis is generated by the final RNase H cleavage of the pregenomic RNA at an 11 nt sequence called…”
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