Search Results - "Lockowandt, Marcus"

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  1. 1

    A comparison of AAV-vector production methods for gene therapy and preclinical assessment by Davidsson, Marcus, Negrini, Matilde, Hauser, Swantje, Svanbergsson, Alexander, Lockowandt, Marcus, Tomasello, Giuseppe, Manfredsson, Fredric P., Heuer, Andreas

    Published in Scientific reports (09-12-2020)
    “…Adeno Associated Virus (AAV)-mediated gene expression in the brain is widely applied in the preclinical setting to investigate the therapeutic potential of…”
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    Journal Article
  2. 2

    GDNF-mediated rescue of the nigrostriatal system depends on the degree of degeneration by Quintino, Luis, Avallone, Martino, Brännstrom, Emil, Kavanagh, Patrick, Lockowandt, Marcus, Garcia Jareño, Patricia, Breger, Ludivine S, Lundberg, Cecilia

    Published in Gene therapy (01-02-2019)
    “…Glial cell-line derived neurotrophic factor (GDNF) is a promising therapeutic molecule to treat Parkinson’s disease. Despite an excellent profile in…”
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    Journal Article
  3. 3

    Optimization of production and transgene expression of a retrogradely transported pseudotyped lentiviral vector by Lockowandt, Marcus, Günther, Dorothee M., Quintino, Luis, Breger, Ludvine S., Isaksson, Christina, Lundberg, Cecilia

    Published in Journal of neuroscience methods (15-04-2020)
    “…•Use of polyethylenimine for 293 T transfection improves consistency of viral titers.•The hSyn promoter is more effective in medium spiny neurons compared to…”
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    Journal Article