Search Results - "Lockhart, K."

Identifying sources of groundwater nitrate contamination in a large alluvial groundwater basin with highly diversified intensive agricultural production by Lockhart, K.M., King, A.M., Harter, T.

“…Groundwater quality is a concern in alluvial aquifers underlying agricultural areas worldwide. Nitrate from land applied fertilizers or from animal waste can…”
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Cytochrome P450-derived eicosanoids and heart function by Jamieson, K Lockhart, Endo, Tomoko, Darwesh, Ahmed M, Samokhvalov, Victor, Seubert, John M

“…The cytochrome P450 monooxygenase system (CYP) is a multigene superfamily of enzymes, which are important in the metabolism of foreign and endogenous…”
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Genetic Deletion or Pharmacological Inhibition of Soluble Epoxide Hydrolase Ameliorates Cardiac Ischemia/Reperfusion Injury by Attenuating NLRP3 Inflammasome Activation by Darwesh, Ahmed M, Keshavarz-Bahaghighat, Hedieh, Jamieson, K Lockhart, Seubert, John M

“…Activation of the nucleotide-binding oligomerization domain-like receptor (NLR) family pyrin domain containing 3 (NLRP3) inflammasome cascade has a role in the…”
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New insights into ventricular arrhythmogenesis in a pure model of pulmonary arterial hypertension by Jamieson, K. Lockhart, Rose, Robert A.

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Impacts of frailty on heart rate variability in aging mice: Roles of the autonomic nervous system and sinoatrial node by Dorey, Tristan W., Jansen, Hailey J., Moghtadaei, Motahareh, Jamieson, K. Lockhart, Rose, Robert A.

“…Heart rate variability (HRV) is determined by intrinsic sinoatrial node (SAN) activity and the autonomic nervous system (ANS). HRV is reduced in aging;…”
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Myocardial Iron Deficiency and Mitochondrial Dysfunction in Advanced Heart Failure in Humans by Zhang, Hao, Jamieson, K Lockhart, Grenier, Justin, Nikhanj, Anish, Tang, Zeyu, Wang, Faqi, Wang, Shaohua, Seidman, Jonathan G, Seidman, Christine E, Thompson, Richard, Seubert, John M, Oudit, Gavin Y

“…Background Myocardial iron deficiency (MID) in heart failure (HF) remains largely unexplored. We aim to establish defining criterion for MID, evaluate its…”
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Is public health training in Canada meeting current needs? Defrosting the paradigm freeze to respond to the post-truth era by Yassi, A., Lockhart, K., Gray, P., Hancock, T.

“…Health scholars have long been calling for a new approach to understanding and responding to public health challenges, recognizing the dynamic influence of…”
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A Slowly Precessing Disk in the Nucleus of M31 as the Feeding Mechanism for a Central Starburst by Lockhart, K. E., Lu, J. R., Peiris, H. V., Rich, R. M., Bouchez, A., Ghez, A. M.

“…We present a kinematic study of the nuclear stellar disk in M31 at infrared wavelengths using high spatial resolution integral field spectroscopy. The spatial…”
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Loss of muscle PDH induces lactic acidosis and adaptive anaplerotic compensation via pyruvate-alanine cycling and glutaminolysis by Gopal, Keshav, Abdualkader, Abdualrahman Mohammed, Li, Xiaobei, Greenwell, Amanda A., Karwi, Qutuba G., Altamimi, Tariq R., Saed, Christina, Uddin, Golam M., Darwesh, Ahmed M., Jamieson, K. Lockhart, Kim, Ryekjang, Eaton, Farah, Seubert, John M., Lopaschuk, Gary D., Ussher, John R., Al Batran, Rami

“…Pyruvate dehydrogenase (PDH) is the rate-limiting enzyme for glucose oxidation that links glycolysis-derived pyruvate with the tricarboxylic acid (TCA) cycle…”
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l‐Citrulline supplementation improves glucose and exercise tolerance in obese male mice by Eshreif, Amina, Al Batran, Rami, Jamieson, K. Lockhart, Darwesh, Ahmed M., Gopal, Keshav, Greenwell, Amanda A., Zlobine, Igor, Aburasayn, Hanin, Eaton, Farah, Mulvihill, Erin E., Campbell, Jonathan E., Seubert, John M., Ussher, John R.

“…New Findings What is the central question of the study? Does the action of l‐citrulline, which has been shown to augment performance in animals and athletes,…”
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Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury by Jamieson, K Lockhart, Darwesh, Ahmed M, Sosnowski, Deanna K, Zhang, Hao, Shah, Saumya, Zhabyeyev, Pavel, Yang, Jun, Hammock, Bruce D, Edin, Matthew L, Zeldin, Darryl C, Oudit, Gavin Y, Kassiri, Zamaneh, Seubert, John M

“…Myocardial infarction (MI) accounts for a significant proportion of death and morbidity in aged individuals. The risk for MI in females increases as they enter…”
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An exploratory study of self‐reported complicated grief symptoms in parentally bereaved adults with intellectual disability by Dodd, P., McEvoy, J., Lockhart, K., Burke, T., O'Keeffe, L., Guerin, S.

“…Background Complicated grief involves the experience of grief‐related symptoms at a time, and severity, beyond which could be considered adaptive, while…”
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Age and Sex Differences in Hearts of Soluble Epoxide Hydrolase Null Mice by Jamieson, K Lockhart, Keshavarz-Bahaghighat, Hedieh, Darwesh, Ahmed M, Sosnowski, Deanna K, Seubert, John M

“…Biological aging is an inevitable part of life that has intrigued individuals for millennia. The progressive decline in biological systems impacts cardiac…”
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Deficiency of Soluble Epoxide Hydrolase Protects Cardiac Function Impaired by LPS-Induced Acute Inflammation by Samokhvalov, Victor, Jamieson, K Lockhart, Darwesh, Ahmed M, Keshavarz-Bahaghighat, Hedieh, Lee, Tim Y T, Edin, Matthew, Lih, Fred, Zeldin, Darryl C, Seubert, John M

“…Lipopolysaccharide (LPS) is a bacterial wall endotoxin producing many pathophysiological conditions including myocardial inflammation leading to…”
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Reforming the workers’ compensation process for occupational lung disease among miners in South Africa: an efficiency study of claims assessment by Barker, S., Ehrlich, R., Spiegel, J. M., Kistnasamy, B., Riera, F., Fourie, A., Mtshali, N., Rabada, M., Lockhart, K., Yassi, A.

“…Purpose The large burden of silicosis and tuberculosis (TB) in the South African mining industry, coupled with an under-resourcing of the compensation agencies…”
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Genetic deletion of soluble epoxide hydrolase provides cardioprotective responses following myocardial infarction in aged mice by Jamieson, K. Lockhart, Samokhvalov, Victor, Akhnokh, Maria K., Lee, Kyra, Cho, Woo Jung, Takawale, Abhijit, Wang, Xiuhua, Kassiri, Zamaneh, Seubert, John M.

“…•Both WT and sEH null mice exhibited a similar age-related decline in overall cardiac function.•SEH deletion preserved cardiac function, reduced cell injury…”
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Glucagon-Like Peptide-1 Protects Against Atrial Fibrillation and Atrial Remodeling in Type 2 Diabetic Mice by Bohne, Loryn J, Jansen, Hailey J, Dorey, Tristan W, Daniel, Irene M, Jamieson, K Lockhart, Belke, Darrell D, McRae, Megan D, Rose, Robert A

“…Atrial fibrillation (AF) is highly prevalent in type 2 diabetes where it increases morbidity and mortality. Glucagon-like peptide (GLP)-1 receptor agonists are…”
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Changes in the Left Ventricular Eicosanoid Profile in Human Dilated Cardiomyopathy by Sosnowski, Deanna K, Jamieson, K Lockhart, Darwesh, Ahmed M, Zhang, Hao, Keshavarz-Bahaghighat, Hedieh, Valencia, Robert, Viveiros, Anissa, Edin, Matthew L, Zeldin, Darryl C, Oudit, Gavin Y, Seubert, John M

“…Metabolites derived from -3 and -6 polyunsaturated fatty acids (PUFAs) have both beneficial and detrimental effects on the heart. However, contribution of…”
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Using a Professional Learning Community Framework to Assist Early Field Experience Students as They Move from Teacher Candidate to Teacher by Nielsen, Curtis P., Lockhart, Amy K.

“…Collaboration is rapidly becoming sacrosanct in today's K-12 schools. A basis for these collaborative school experiences is the ability to share one's…”
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Specialist breast care nurses for supportive care of women with breast cancer by Cruickshank, S, Kennedy, C, Lockhart, K, Dosser, I, Dallas, L

“…Breast Care Nurses (BCNs) are now established internationally, predominantly in well resourced healthcare systems. The role of BCNs has expanded to reflect the…”
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