Search Results - "Lockey, Richard"

Airway smooth muscle pathophysiology in asthma by Camoretti-Mercado, Blanca, Lockey, Richard F.

“…The airway smooth muscle (ASM) cell plays a central role in the pathogenesis of asthma and constitutes an important target for treatment. These cells control…”
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Soluble ACE2 as a potential therapy for COVID-19 by Krishnamurthy, Sudarshan, Lockey, Richard F, Kolliputi, Narasaiah

“…Soluble angiotensin-converting enzyme 2 (sACE2) could be a therapeutic option to treat coronavirus disease 2019 (COVID-19) infection. Severe acute respiratory…”
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4-Hydroxy-2-nonenal: a critical target in oxidative stress? by Breitzig, Mason, Bhimineni, Charishma, Lockey, Richard, Kolliputi, Narasaiah

“…In this perspective, we summarize and discuss critical advancements in the study of 4-hydroxy-2-nonenal (4-HNE) as it relates to diseases and clinical…”
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Acute asthma, prognosis, and treatment by Fergeson, Jennifer E., DO, Patel, Shiven S., MD, Lockey, Richard F., MD

“…Asthma affects about 300 million people globally and accounts for 1 in every 250 deaths in the world. Approximately 12 million people in the United States each…”
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Speaking the same language: The World Allergy Organization Subcutaneous Immunotherapy Systemic Reaction Grading System by Cox, Linda, MD, Larenas-Linnemann, Desiree, MD, Lockey, Richard F., MD, Passalacqua, Giovanni, MD

“…Subcutaneous allergen immunotherapy (SCIT) is an effective treatment for allergic rhinitis, asthma and venom hypersensitivity and has the potential of…”
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Bitter taste receptors in the treatment of asthma: Opportunities and challenges by Camoretti-Mercado, Blanca, Lockey, Richard F.

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Pyroptosis Inhibition in Disease Treatment: Opportunities and Challenges by Bandharam, Navya, Lockey, Richard F., Kolliputi, Narasaiah

“…Programmed cell death (PCD) is at the center of immune responses, with different types of PCD occurring based on bodily conditions at a given moment. The main…”
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Obesity and Hormonal Influences on Asthma: Mechanisms, Management Challenges, and Emerging Therapeutic Strategies by Weare-Regales, Natalia, Carr, Tara, Holguin, Fernando, Tibbitt, Christopher Andrew, Lockey, Richard F

“…Obesity and hormonal dysregulation, common comorbidities of asthma, not only influence asthma risk and onset but can also complicate its management. The…”
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The β-adrenergic theory of bronchial asthma: 50 years later by Camoretti-Mercado, Blanca, Lockey, Richard F.

“…[...]undesired actions of isoprenaline on various organs caused by its nonselectivity were considered to be at the root of the increased mortality of young…”
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Mir-206 regulates pulmonary artery smooth muscle cell proliferation and differentiation by Jalali, Samuel, Ramanathan, Gurukumar K, Parthasarathy, Prasanna Tamarapu, Aljubran, Salman, Galam, Lakshmi, Yunus, Asfiya, Garcia, Sara, Cox, Jr, Ruan R, Lockey, Richard F, Kolliputi, Narasaiah

“…Pulmonary Arterial Hypertension (PAH) is a progressive devastating disease characterized by excessive proliferation of the Pulmonary Arterial Smooth Muscle…”
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Pharmacokinetic and pharmacodynamic comparison of epinephrine, administered intranasally and intramuscularly: An integrated analysis by Tanimoto, Sarina, Kaliner, Michael, Lockey, Richard F, Ebisawa, Motohiro, Koplowitz, Luana Pesco, Koplowitz, Barry, Lowenthal, Richard

“…Manual intramuscular epinephrine injection is the standard of care for treating severe allergic reactions and anaphylaxis. Epinephrine autoinjectors were…”
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Mind-body connection: metabolite 4-ethylphenyl linked to anxiety behavior and oligodendrocyte modification in autism spectrum disorder by Pascual, Francisco, Camilli, Samuel, Lockey, Richard F, Kolliputi, Narasaiah

“…The connection between byproducts of digestion in the gastrointestinal (GI) tract and neurocognitive disorders is an expanding area of research that has…”
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Asthma and carotid artery plaques by Cardet, Juan Carlos, Weare-Regales, Natalia, Lockey, Richard F.

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World Allergy Organization Systemic Allergic Reaction Grading System: Is a Modification Needed? by Cox, Linda S., MD, Sanchez-Borges, Mario, MD, Lockey, Richard F., MD

“…There is no universally accepted grading system to classify the severity of systemic allergic reactions (SARs), including anaphylaxis. Although a consensus…”
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International consensus on (ICON) anaphylaxis by Simons, F Estelle R, Ardusso, Ledit Rf, Bilò, M Beatrice, Cardona, Victoria, Ebisawa, Motohiro, El-Gamal, Yehia M, Lieberman, Phil, Lockey, Richard F, Muraro, Antonella, Roberts, Graham, Sanchez-Borges, Mario, Sheikh, Aziz, Shek, Lynette P, Wallace, Dana V, Worm, Margitta

“…ICON: Anaphylaxis provides a unique perspective on the principal evidence-based anaphylaxis guidelines developed and published independently from 2010 through…”
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Deletion of P2X7 attenuates hyperoxia-induced acute lung injury via inflammasome suppression by Galam, Lakshmi, Rajan, Ashna, Failla, Athena, Soundararajan, Ramani, Lockey, Richard F, Kolliputi, Narasaiah

“…Increasing evidence shows that hyperoxia is a serious complication of oxygen therapy in acutely ill patients that causes excessive production of free radicals…”
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Grading local side effects of sublingual immunotherapy for respiratory allergy: Speaking the same language by Passalacqua, Giovanni, MD, Baena-Cagnani, Carlos E., MD, Bousquet, Jean, MD, Canonica, Giorgio Walter, MD, Casale, Thomas B., MD, Cox, Linda, MD, Durham, Stephen R., MD, Larenas-Linnemann, Desiréé, MD, Ledford, Dennis, MD, Pawankar, Ruby, MD, Potter, Paul, MD, Rosario, Nelson, MD, Wallace, Dana, MD, Lockey, Richard F., MD

“…Sublingual immunotherapy (SLIT) is increasingly used worldwide. Despite its safety being well ascertained, there is no universally accepted system to grade and…”
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The role of the NLRP3 inflammasome in pulmonary diseases by Hosseinian, Nima, Cho, Young, Lockey, Richard F, Kolliputi, Narasaiah

“…Respiratory diseases and lung injuries are one of the leading causes of death in the world. One critical component of these diseases is exaggerated…”
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Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA): A summary report by Fiocchi, Alessandro, MD, Schünemann, Holger J., MD, PhD, Brozek, Jan, MD, Restani, Patrizia, PhD, Beyer, Kirsten, MD, Troncone, Riccardo, MD, Martelli, Alberto, MD, Terracciano, Luigi, MD, Bahna, Sami L., MD, Rancé, Fabienne, MD, Ebisawa, Motohiro, MD, Heine, Ralf G., MD, FRACP, Assa'ad, Amal, MD, Sampson, Hugh, MD, Verduci, Elvira, MD, Bouygue, G.R., MSc, Baena-Cagnani, Carlos, MD, Canonica, Walter, MD, Lockey, Richard F., MD

“…The 2nd Milan Meeting on Adverse Reactions to Bovine Proteins was the venue for the presentation of the first consensus-based approach to the management of…”
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2015 update of the evidence base: World Allergy Organization anaphylaxis guidelines by Simons, F Estelle R, Ebisawa, Motohiro, Sanchez-Borges, Mario, Thong, Bernard Y, Worm, Margitta, Tanno, Luciana Kase, Lockey, Richard F, El-Gamal, Yehia M, Brown, Simon Ga, Park, Hae-Sim, Sheikh, Aziz

“…The World Allergy Organization (WAO) Guidelines for the assessment and management of anaphylaxis provide a unique global perspective on this increasingly…”
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