Search Results - "Lockett, S"
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1
high-throughput system for segmenting nuclei using multiscale techniques
Published in Cytometry. Part A (01-05-2008)“…Automatic segmentation of cell nuclei is critical in several high-throughput cytometry applications whereas manual segmentation is laborious and…”
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Segmentation of nuclei and cells using membrane related protein markers
Published in Journal of microscopy (Oxford) (01-03-2001)“…Segmenting individual cell nuclei from microscope images normally involves volume labelling of the nuclei with a DNA stain. However, this method often fails…”
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Using a semi-structured interview to explore imagery experienced during social anxiety for clients with a diagnosis of psychosis: an exploratory study conducted within an early intervention for psychosis service
Published in Behavioural and cognitive psychotherapy (01-01-2012)“…Social phobia frequently occurs as a comorbid condition, with high rates reported among people with psychosis. Little is known about the nature of social…”
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The Transformation Suppressor Pdcd4 Is a Novel Eukaryotic Translation Initiation Factor 4A Binding Protein That Inhibits Translation
Published in Molecular and Cellular Biology (01-01-2003)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Segmentation of confocal microscope images of cell nuclei in thick tissue sections
Published in Journal of microscopy (Oxford) (01-03-1999)“…Summary Segmentation of intact cell nuclei from three‐dimensional (3D) images of thick tissue sections is an important basic capability necessary for many…”
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Calibration and standardization of the emission light path of confocal microscopes
Published in Journal of microscopy (Oxford) (01-07-2006)“…Summary Recently, there has been a large expansion in the usage of optical microscopes for obtaining quantitative information from biological samples in order…”
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A geometric model for 3-D confocal image analysis
Published in IEEE transactions on biomedical engineering (01-12-2000)“…The authors use partial-differential-equation-based filtering as a preprocessing and post processing strategy for computer-aided cytology. They wish to…”
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Identification of Probabilistic Transcriptional Switches in the Ly49 Gene Cluster: A Eukaryotic Mechanism for Selective Gene Activation
Published in Immunity (Cambridge, Mass.) (01-07-2004)“…Murine natural killer cells selectively express members of the Ly49 family of class I MHC receptors; however, the molecular mechanism controlling probabilistic…”
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The Caenorhabditis elegans Dosage Compensation Machinery Is Recruited to X Chromosome DNA Attached to an Autosome
Published in Genetics (Austin) (01-12-2000)“…The dosage compensation machinery of Caenorhabditis elegans is targeted specifically to the X chromosomes of hermaphrodites (XX) to reduce gene expression by…”
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Co-localization of the tumor-suppressor protein p53 and human papillomavirus E6 protein in human cervical carcinoma cell lines
Published in Oncogene (01-10-1993)“…The loss of the tumor-suppressor activity of p53, either by mutation or by interaction with the human papillomavirus (HPV) E6 protein, is considered to be an…”
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Effect of Chemokine Receptor Mutations on Heterosexual Human Immunodeficiency Virus Transmission
Published in The Journal of infectious diseases (01-09-1999)“…To assess the effect of mutations at the CCR-2 and CCR-5 loci on heterosexual human immunodeficiency virus (HIV) transmission, 144 persons heterosexually…”
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Automatic and Quantitative Measurement of Protein-Protein Colocalization in Live Cells
Published in Biophysical journal (01-06-2004)“…We introduce a novel statistical approach that quantifies, for the first time, the amount of colocalization of two fluorescent-labeled proteins in an image…”
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Three-dimensional image visualization and analysis
Published in Current protocols in cytometry (01-05-2001)“…This unit introduces the concepts of 3D image analysis and visualization as applied in cytometry. The author discusses the nature of 3D data sets and describes…”
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Senescent Fibroblasts Promote Epithelial Cell Growth and Tumorigenesis: A Link between Cancer and Aging
Published in Proceedings of the National Academy of Sciences - PNAS (09-10-2001)“…Mammalian cells can respond to damage or stress by entering a state of arrested growth and altered function termed cellular senescence. Several lines of…”
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Activation of Toll-like Receptor 2 on Microglia Promotes Cell Uptake of Alzheimer Disease-associated Amyloid β Peptide
Published in The Journal of biological chemistry (10-02-2006)“…The human G-protein-coupled formyl peptide receptor-like 1 (FPRL1) and its mouse homologue mFPR2 mediate the chemotactic activity of a variety of polypeptides…”
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Intensity-based energy transfer measurements in digital imaging microscopy
Published in European biophysics journal (01-01-1998)“…Investigation of protein-protein associations is important in understanding structure and function relationships in living cells. Using Förster-type resonance…”
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Modulation of lens cell adhesion molecules by particle beams
Published in Physica medica (2001)“…Cell adhesion molecules (CAMs) are proteins which anchor cells to each other and to the extracellular matrix (ECM), but whose functions also include signal…”
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Mismatched Human Leukocyte Antigen Alleles Protect Against Heterosexual HIV Transmission
Published in Journal of acquired immune deficiency syndromes (1999) (01-07-2001)“…Genetic variation at the human leukocyte antigen (HLA) loci has been shown to be an important risk factor for progression to HIV disease, but its significance…”
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Quantitative precision of an automated, fluorescence-based image cytometer
Published in Analytical and quantitative cytology and histology (01-06-1992)“…Digital image-based cytometry of clinical specimens labeled with fluorescent, disease-specific markers holds promise for becoming an important diagnostic and…”
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