Search Results - "Lockett, Jack"
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Glucocorticoids and Their Receptor Isoforms: Roles in Female Reproduction, Pregnancy, and Foetal Development
Published in Biology (Basel, Switzerland) (01-08-2023)“…Alterations in the hypothalamic–pituitary–adrenal (HPA) axis and associated changes in circulating levels of glucocorticoids are integral to an organism’s…”
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Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitis
Published in Nature communications (29-05-2024)“…Metabolic dysfunction-associated steatohepatitis (MASH) is the most prevalent cause of liver disease worldwide, with a single approved therapeutic. Previous…”
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Dietary supplements, guideline alignment and biochemical nutrient status in pregnancy: Findings from the Queensland Family Cohort pilot study
Published in Maternal and child nutrition (01-01-2024)“…In high‐income nations, multiple micronutrient (MMN) supplementation during pregnancy is a common practice. We aimed to describe maternal characteristics…”
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Investigation and management of moderate to severe inpatient hyponatraemia in an Australian tertiary hospital
Published in BMC endocrine disorders (06-12-2018)“…Hyponatraemia is the most common electrolyte disturbance amongst hospitalised patients. Both American and European guidelines recommend fluid restriction as…”
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Maternal stress, anxiety, and depression are all associated with increased placental glucocorticoid receptor D1 isoform expression
Published in Placenta (Eastbourne) (07-09-2023)Get full text
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The Glucocorticoid Receptor: Isoforms, Functions, and Contribution to Glucocorticoid Sensitivity
Published in Endocrine reviews (12-07-2024)“…Abstract Glucocorticoids exert pleiotropic effects on all tissues to regulate cellular and metabolic homeostasis. Synthetic forms are used therapeutically in a…”
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Urea treatment in fluid restriction‐refractory hyponatraemia
Published in Clinical endocrinology (Oxford) (01-04-2019)“…Summary Objective Hyponatraemia in hospitalized patients is common and associated with increased mortality. International guidelines give conflicting advice…”
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119-LB: Targeted IL-22 Improves Glucose Tolerance and Reduces Hepatic Steatosis and Hepatic Fibrosis in Murine Models of Diabetes and Liver Disease
Published in Diabetes (New York, N.Y.) (01-06-2022)“…The cytokine interleukin-22 (IL-22) is an inhibitor of cellular stress. In HFD murine models, systemic IL-22 is efficacious to restore glucose tolerance,…”
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The impact of obesity and uncontrolled asthma during pregnancy on metabolic and inflammatory pathways
Published in The Journal of asthma (03-06-2023)“…Asthma and obesity are both inflammatory complications of pregnancy and when combined contribute to an increased risk of uncontrolled asthma during pregnancy…”
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Atypical Tibial Fracture in a 63-Year-Old Woman With Intermittent Use of Bisphosphonate Unmasking Hypophosphatasia
Published in Journal of the Endocrine Society (01-11-2019)“…Abstract We report an unusual case of atypical proximal tibial stress fracture (APTF) associated with intermittent use of bisphosphonates (BPs) and…”
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Transvesical ureterotomy of intersphincteric duplex ureter for an obstructed upper pole moiety
Published in Journal of clinical urology (01-05-2017)Get full text
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