Search Results - "Lockery, Shawn R"

The computational worm: spatial orientation and its neuronal basis in C. elegans by Lockery, Shawn R

“…Highlights ► C. elegans exhibits two forms of spatial orientation behavior, klinokinesis and klinotaxis, both of which require computation of the time…”
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Theory and practice of using cell strainers to sort Caenorhabditis elegans by size by Lanier, Vincent J, White, Amanda M, Faumont, Serge, Lockery, Shawn R

“…The nematode Caenorhabditis elegans is a model organism widely used in basic, translational, and industrial research. C. elegans development is characterized…”
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Even-Skipped+ Interneurons Are Core Components of a Sensorimotor Circuit that Maintains Left-Right Symmetric Muscle Contraction Amplitude by Heckscher, Ellie S., Zarin, Aref Arzan, Faumont, Serge, Clark, Matthew Q., Manning, Laurina, Fushiki, Akira, Schneider-Mizell, Casey M., Fetter, Richard D., Truman, James W., Zwart, Maarten F., Landgraf, Matthias, Cardona, Albert, Lockery, Shawn R., Doe, Chris Q.

“…Bilaterally symmetric motor patterns—those in which left-right pairs of muscles contract synchronously and with equal amplitude (such as breathing,…”
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C. elegans Notch Signaling Regulates Adult Chemosensory Response and Larval Molting Quiescence by Singh, Komudi, Chao, Michael Y., Somers, Gerard A., Komatsu, Hidetoshi, Corkins, Mark E., Larkins-Ford, Jonah, Tucey, Tim, Dionne, Heather M., Walsh, Melissa B., Beaumont, Emma K., Hart, Douglas P., Lockery, Shawn R., Hart, Anne C.

“…The conserved DOS-motif proteins OSM-7 and OSM-11 function as coligands with canonical DSL (Delta, Serrate, and LAG-2) ligands to activate C. elegans Notch…”
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Functional asymmetry in Caenorhabditis elegans taste neurons and its computational role in chemotaxis by Lockery, Shawn R, Suzuki, Hiroshi, Thiele, Tod R, Faumont, Serge, Ezcurra, Marina, Schafer, William R

“…Chemotaxis in Caenorhabditis elegans, like chemotaxis in bacteria, involves a random walk biased by the time derivative of attractant concentration, but how…”
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Optogenetic analysis of synaptic transmission in the central nervous system of the nematode Caenorhabditis elegans by Lindsay, Theodore H., Thiele, Tod R., Lockery, Shawn R.

“…A reliable method for recording evoked synaptic events in identified neurons in Caenorhabditis elegans would greatly accelerate our understanding of its…”
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An image-free opto-mechanical system for creating virtual environments and imaging neuronal activity in freely moving Caenorhabditis elegans by Faumont, Serge, Rondeau, Gary, Thiele, Tod R, Lawton, Kristy J, McCormick, Kathryn E, Sottile, Matthew, Griesbeck, Oliver, Heckscher, Ellie S, Roberts, William M, Doe, Chris Q, Lockery, Shawn R

“…Non-invasive recording in untethered animals is arguably the ultimate step in the analysis of neuronal function, but such recordings remain elusive. To address…”
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Microfluidic devices for analysis of spatial orientation behaviors in semi-restrained Caenorhabditis elegans by McCormick, Kathryn E, Gaertner, Bryn E, Sottile, Matthew, Phillips, Patrick C, Lockery, Shawn R

“…This article describes the fabrication and use of microfluidic devices for investigating spatial orientation behaviors in nematode worms (Caenorhabditis…”
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The nematode worm C. elegans chooses between bacterial foods as if maximizing economic utility by Katzen, Abraham, Chung, Hui-Kuan, Harbaugh, William T, Della Iacono, Christina, Jackson, Nicholas, Glater, Elizabeth E, Taylor, Charles J, Yu, Stephanie K, Flavell, Steven W, Glimcher, Paul W, Andreoni, James, Lockery, Shawn R

“…In value-based decision making, options are selected according to subjective values assigned by the individual to available goods and actions. Despite the…”
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Anthelmintic drug actions in resistant and susceptible C. elegans revealed by electrophysiological recordings in a multichannel microfluidic device by Weeks, Janis C., Robinson, Kristin J., Lockery, Shawn R., Roberts, William M.

“…Many anthelmintic drugs used to treat parasitic nematode infections target proteins that regulate electrical activity of neurons and muscles: ion channels…”
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The Neural Network for Chemotaxis to Tastants in Caenorhabditis elegans Is Specialized for Temporal Differentiation by Thiele, Tod R, Faumont, Serge, Lockery, Shawn R

“…Chemotaxis in Caenorhabditis elegans depends critically on the rate of change of attractant concentration computed as the worm moves through its environment…”
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A stochastic neuronal model predicts random search behaviors at multiple spatial scales in C. elegans by Roberts, William M, Augustine, Steven B, Lawton, Kristy J, Lindsay, Theodore H, Thiele, Tod R, Izquierdo, Eduardo J, Faumont, Serge, Lindsay, Rebecca A, Britton, Matthew Cale, Pokala, Navin, Bargmann, Cornelia I, Lockery, Shawn R

“…Random search is a behavioral strategy used by organisms from bacteria to humans to locate food that is randomly distributed and undetectable at a distance. We…”
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Single-cell transcriptional analysis of taste sensory neuron pair in Caenorhabditis elegans by Takayama, Jun, Faumont, Serge, Kunitomo, Hirofumi, Lockery, Shawn R, Iino, Yuichi

“…The nervous system is composed of a wide variety of neurons. A description of the transcriptional profiles of each neuron would yield enormous information…”
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Microfluidic platform for electrophysiological recordings from host-stage hookworm and Ascaris suum larvae: A new tool for anthelmintic research by Weeks, Janis C., Roberts, William M., Robinson, Kristin J., Keaney, Melissa, Vermeire, Jon J., Urban, Joseph F., Lockery, Shawn R., Hawdon, John M.

“…The screening of candidate compounds and natural products for anthelmintic activity is important for discovering new drugs against human and animal parasites…”
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Characterization of Drosophila larval crawling at the level of organism, segment, and somatic body wall musculature by Heckscher, Ellie S, Lockery, Shawn R, Doe, Chris Q

“…Understanding rhythmic behavior at the developmental and genetic levels has important implications for neurobiology, medicine, evolution, and robotics. We…”
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The conserved endocannabinoid anandamide modulates olfactory sensitivity to induce hedonic feeding in C. elegans by Levichev, Anastasia, Faumont, Serge, Berner, Rachel Z., Purcell, Zhifeng, White, Amanda M., Chicas-Cruz, Kathy, Lockery, Shawn R.

“…The ability of cannabis to increase food consumption has been known for centuries. In addition to producing hyperphagia, cannabinoids can amplify existing…”
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The homeobox gene lim-6 is required for distinct chemosensory representations in C. elegans by Lockery, Shawn R, Pierce-Shimomura, Jonathan T, Faumont, Serge, Gaston, Michelle R, Pearson, Bret J

“…The ability to discriminate between different chemical stimuli is crucial for food detection, spatial orientation and other adaptive behaviours in animals. In…”
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Evolution and analysis of minimal neural circuits for klinotaxis in Caenorhabditis elegans by Izquierdo, Eduardo J, Lockery, Shawn R

“…Chemotaxis during sinusoidal locomotion in nematodes captures in simplified form the general problem of how dynamical interactions between the nervous system,…”
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Analysis of the effects of turning bias on chemotaxis in C. elegans by Pierce-Shimomura, Jonathan T, Dores, Michael, Lockery, Shawn R

“…C. elegans advances up a chemical gradient by modulating the probability of occasional large, course-correcting turns called pirouettes. However, it remains…”
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Microinjection in C. elegans by direct penetration of elastomeric membranes by Lockery, Shawn R., Pop, Stelian, Jussila, Benjamin

“…The nematode worm C. elegans is widely used in basic and translational research. The creation of transgenic strains by injecting DNA constructs into the worm's…”
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