Search Results - "Locher, Clara"

A survey of biomedical journals to detect editorial bias and nepotistic behavior by Scanff, Alexandre, Naudet, Florian, Cristea, Ioana A, Moher, David, Bishop, Dorothy V M, Locher, Clara

“…Alongside the growing concerns regarding predatory journal growth, other questionable editorial practices have gained visibility recently. Among them, we…”
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Data-sharing and re-analysis for main studies assessed by the European Medicines Agency-a cross-sectional study on European Public Assessment Reports by Siebert, Maximilian, Gaba, Jeanne, Renault, Alain, Laviolle, Bruno, Locher, Clara, Moher, David, Naudet, Florian

“…Transparency and reproducibility are expected to be normative practices in clinical trials used for decision-making on marketing authorisations for new…”
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An Immunosurveillance Mechanism Controls Cancer Cell Ploidy by Senovilla, Laura, Vitale, Ilio, Martins, Isabelle, Tailler, Maximilien, Pailleret, Claire, Michaud, Mickaël, Galluzzi, Lorenzo, Adjemian, Sandy, Kepp, Oliver, Niso-Santano, Mireia, Shen, Shensi, Mariño, Guillermo, Criollo, Alfredo, Boilève, Alice, Job, Bastien, Ladoire, Sylvain, Ghiringhelli, François, Sistigu, Antonella, Yamazaki, Takahiro, Rello-Varona, Santiago, Locher, Clara, Poirier-Colame, Vichnou, Talbot, Monique, Valent, Alexander, Berardinelli, Francesco, Antoccia, Antonio, Ciccosanti, Fabiola, Fimia, Gian Maria, Piacentini, Mauro, Fueyo, Antonio, Messina, Nicole L., Li, Ming, Chan, Christopher J., Sigl, Verena, Pourcher, Guillaume, Ruckenstuhl, Christoph, Carmona-Gutierrez, Didac, Lazar, Vladimir, Penninger, Josef M., Madeo, Frank, López-Otín, Carlos, Smyth, Mark J., Zitvogel, Laurence, Castedo, Maria, Kroemer, Guido

“…Cancer cells accommodate multiple genetic and epigenetic alterations that initially activate intrinsic (cell-autonomous) and extrinsic (immune-mediated)…”
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Immune Infiltrates Are Prognostic Factors in Localized Gastrointestinal Stromal Tumors by RUSAKIEWICZ, Sylvie, SEMERARO, Michaela, CHAIGNEAU, Loic, LE BRUN-LY, Valérie, DUBREUIL, Patrice, CREMER, Isabelle, CAIGNARD, Anne, POIRIER-COLAME, Vichnou, CHABA, Kariman, FLAMENT, Caroline, HALAMA, Niels, JÄGER, Dirk, SARABI, Matthieu, EGGERMONT, Alexander, BONVALOT, Sylvie, COMMO, Frédéric, TERRIER, Philippe, OPOLON, Paule, EMILE, Jean-François, COINDRE, Jean-Michel, KROEMER, Guido, CHAPUT, Nathalie, LE CESNE, Axel, DESBOIS, Mélanie, BLAY, Jean-Yves, ZITVOGEL, Laurence, LOCHER, Clara, MENDEZ, Rosa, VIMOND, Nadège, CONCHA, Angel, GARRIDO, Federico, ISAMBERT, Nicolas

“…Cancer immunosurveillance relies on effector/memory tumor-infiltrating CD8(+) T cells with a T-helper cell 1 (TH1) profile. Evidence for a natural killer (NK)…”
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Correction: A survey of biomedical journals to detect editorial bias and nepotistic behavior by Scanff, Alexandre, Naudet, Florian, Cristea, Ioana A, Moher, David, Bishop, Dorothy V M, Locher, Clara

“…[This corrects the article DOI: 10.1371/journal.pbio.3001133.]…”
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Combined evaluation of LC3B puncta and HMGB1 expression predicts residual risk of relapse after adjuvant chemotherapy in breast cancer by Ladoire, Sylvain, Penault-Llorca, Frédérique, Senovilla, Laura, Dalban, Cécile, Enot, David, Locher, Clara, Prada, Nicole, Poirier-Colame, Vichnou, Chaba, Kariman, Arnould, Laurent, Ghiringhelli, François, Fumoleau, Pierre, Spielmann, Marc, Delaloge, Suzette, Poillot, Marie Laure, Arveux, Patrick, Goubar, Aicha, Andre, Fabrice, Zitvogel, Laurence, Kroemer, Guido

“…In spite of adjuvant chemotherapy, a significant fraction of patients with localized breast cancer (BC) relapse after optimal treatment. We determined the…”
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The dendritic cell–tumor cross-talk in cancer by Ma, Yuting, Aymeric, Laetitia, Locher, Clara, Kroemer, Guido, Zitvogel, Laurence

“…The question as to whether the tumor grows because of or despite the host immune system is being progressively addressed with refined technology, gene…”
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Reporting of interventional clinical trial results in an academic center: a survey of completed studies by Alix-Doucet, Anne Sophie, Vinatier, Constant, Fin, Loïc, Léna, Hervé, Rangé, Hélène, Locher, Clara, Naudet, Florian

“…The dissemination of clinical trial results is an important scientific and ethical endeavour. This survey of completed interventional studies in a French…”
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Tivozanib in renal cell carcinoma: a systematic review of the evidence and its dissemination in the scientific literature by Caquelin, Laura, Gewily, Mohamed, Mottais, Wendy, Tebaldi, Chloé, Laviolle, Bruno, Naudet, Florian, Locher, Clara

“…Tivozanib (Fotivda) is an anti-angiogenic tyrosine kinase inhibitor that was denied access to the US market by the Food and Drug Administration (FDA). In…”
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Chemotherapy and radiotherapy: Cryptic anticancer vaccines by Ma, Yuting, Kepp, Oliver, Ghiringhelli, François, Apetoh, Lionel, Aymeric, Laetitia, Locher, Clara, Tesniere, Antoine, Martins, Isabelle, Ly, André, Haynes, Nicole M, Smyth, Mark J, Kroemer, Guido, Zitvogel, Laurence

“…Abstract An attractive, yet hitherto unproven concept predicts that the promotion of tumor regression should elicit the host's immune response against residual…”
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How to improve the immunogenicity of chemotherapy and radiotherapy by Ma, Yuting, Conforti, Rosa, Aymeric, Laetitia, Locher, Clara, Kepp, Oliver, Kroemer, Guido, Zitvogel, Laurence

“…Chemotherapy or radiotherapy could induce various tumor cell death modalities, releasing tumor-derived antigen as well as danger signals that could either be…”
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Outcome of patients treated with molecular adsorbent recirculating system albumin dialysis: A national multicenter study by Camus, Christophe, Locher, Clara, Saliba, Faouzi, Goubaux, Bernard, Bonadona, Agnès, Lavayssiere, Laurence, Paugam, Catherine, Quinart, Alice, Barbot, Olivier, Dharancy, Sébastien, Delafosse, Bertrand, Pichon, Nicolas, Barraud, Hélène, Galbois, Arnaud, Veber, Benoit, Cayot, Sophie, Souche, Bruno

“…Background and Aim The molecular adsorbent recirculating system (MARS) is the most widely used device to treat liver failure. Nevertheless, data from…”
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Upstream ORF affects MYCN translation depending on exon 1b alternative splicing by Besançon, Roger, Valsesia-Wittmann, Sandrine, Locher, Clara, Delloye-Bourgeois, Céline, Furhman, Lydie, Tutrone, Giovani, Bertrand, Christophe, Jallas, Anne-Catherine, Garin, Elisabeth, Puisieux, Alain

“…The MYCN gene is transcribed into two major mRNAs: one full-length (MYCN) and one exon 1b-spliced (MYCNDelta1b) mRNA. But nothing is known about their…”
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Pharmacologically controlled drinking in the treatment of alcohol dependence or alcohol use disorders: a systematic review with direct and network meta‐analyses on nalmefene, naltrexone, acamprosate, baclofen and topiramate by Palpacuer, Clément, Duprez, Renan, Huneau, Alexandre, Locher, Clara, Boussageon, Rémy, Laviolle, Bruno, Naudet, Florian

“…Background and Aims Pharmacologically controlled drinking in the treatment of alcohol dependence or alcohol use disorders (AUDs) is an emerging concept. Our…”
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Simultaneous Versus Delayed Resection for Initially Resectable Synchronous Colorectal Cancer Liver Metastases: A Prospective, Open-label, Randomized, Controlled Trial by Boudjema, Karim, Locher, Clara, Sabbagh, Charles, Ortega-Deballon, Pablo, Heyd, Bruno, Bachellier, Philippe, Métairie, Sylvie, Paye, François, Bourlier, Pascal, Adam, René, Merdrignac, Aude, Tual, Christelle, Le Pabic, Estelle, Sulpice, Laurent, Meunier, Bernard, Regimbeau, Jean-Marc, Bellissant, Eric

“…OBJECTIVE:To answer whether synchronous colorectal cancer liver metastases (SLM) should be resected simultaneously with primary cancer or should be delayed…”
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Making data sharing the norm in medical research by Locher, Clara, Le Goff, Gérard, Le Louarn, Anne, Mansmann, Ulrich, Naudet, Florian

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Replication of systematic reviews: is it to the benefit or detriment of methodological quality? by Chapelle, Céline, Ollier, Edouard, Bonjean, Paul, Locher, Clara, Zufferey, Paul Jacques, Cucherat, Michel, Laporte, Silvy

“…To perform an overview of the overlap of systematic reviews (SRs) assessing direct oral anticoagulants and characterize these reviews in terms of bias and…”
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Crosstalk between ER stress and immunogenic cell death by Kepp, Oliver, Menger, Laurie, Vacchelli, Erika, Locher, Clara, Adjemian, Sandy, Yamazaki, Takahiro, Martins, Isabelle, Sukkurwala, Abdul Qader, Michaud, Michael, Senovilla, Laura, Galluzzi, Lorenzo, Kroemer, Guido, Zitvogel, Laurence

“…Abstract Preclinical and clinical findings suggest that tumor-specific immune responses may be responsible – at least in part – for the clinical success of…”
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The evidence base of US Food and Drug Administration approvals of novel cancer therapies from 2000 to 2020 by Gloy, Viktoria, Schmitt, Andreas M., Düblin, Pascal, Hirt, Julian, Axfors, Cathrin, Kuk, Hanna, Pereira, Tiago V., Locher, Clara, Caquelin, Laura, Walter‐Claudi, Martin, Lythgoe, Mark P., Herbrand, Amanda, Kasenda, Benjamin, Hemkens, Lars G.

“…Concerns have been raised that regulatory programs to accelerate approval of cancer drugs in cancer may increase uncertainty about benefits and harms for…”
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Clinical trials during pandemics and beyond: time for a more efficient pharmacological strategy by Lemaitre, Florian, Locher, Clara, Verdier, Marie-Clémence, Naudet, Florian

“…Abstract During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, clinical trials on antiviral or symptomatic drugs have been…”
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