Search Results - "Locco, Louis"

Small Interfering RNA Screens Reveal Enhanced Cisplatin Cytotoxicity in Tumor Cells Having both BRCA Network and TP53 Disruptions by Bartz, Steven R., Zhang, Zhan, Burchard, Julja, Imakura, Maki, Martin, Melissa, Palmieri, Anthony, Needham, Rachel, Guo, Jie, Gordon, Marcia, Chung, Namjin, Warrener, Paul, Jackson, Aimee L., Carleton, Michael, Oatley, Melissa, Locco, Louis, Santini, Francesca, Smith, Todd, Kunapuli, Priya, Ferrer, Marc, Strulovici, Berta, Friend, Stephen H., Linsley, Peter S.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Median absolute deviation to improve hit selection for genome-scale RNAi screens by Chung, Namjin, Zhang, Xiaohua Douglas, Kreamer, Anthony, Locco, Louis, Kuan, Pei-Fen, Bartz, Steven, Linsley, Peter S, Ferrer, Marc, Strulovici, Berta

“…High-throughput screening (HTS) of large-scale RNA interference (RNAi) libraries has become an increasingly popular method of functional genomics in recent…”
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Endogenous syntaxins 2, 3 and 4 exhibit distinct but overlapping patterns of expression at the hepatocyte plasma membrane by Fujita, H, Tuma, P L, Finnegan, C M, Locco, L, Hubbard, A L

“…To investigate the mechanisms regulating polarized vesicle delivery to the cell surface in hepatocytes, we have characterized the endogenous plasma membrane…”
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6H-Benzo[c]chromen-6-one derivatives as selective ERβ agonists by Sun, Wanying, Cama, Lovji D., Birzin, Elizabeth T., Warrier, Sudha, Locco, Louis, Mosley, Ralph, Hammond, Milton L., Rohrer, Susan P.

“…A series of 6H-benzo[c]chromen-6-one and 6H-benzo[c]chromene derivatives were prepared. Many of the analogs were found to be potent and selective ERβ agonists…”
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A multiplexed siRNA screening strategy to identify genes in the PARP pathway by Stec, Erica, Locco, Louis, Szymanski, Stacey, Bartz, Steven R, Toniatti, Carlo, Needham, Rachel H V, Palmieri, Anthony, Carleton, Michael, Cleary, Michele A, Jackson, Aimee L, Linsley, Peter S, Strulovici, Berta, Ferrer, Marc, Santini, Francesca

“…Gene silencing by RNA interference has become a powerful tool to help identify genes that regulate biological processes. However, the complexity of the biology…”
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An efficient and fully automated high-throughput transfection method for genome-scale siRNA screens by Chung, Namjin, Locco, Louis, Huff, Kevin W, Bartz, Steven, Linsley, Peter S, Ferrer, Marc, Strulovici, Berta

“…RNA interference (RNAi), combined with the availability of genome sequences, provides an unprecedented opportunity for the massive and parallel investigations…”
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A 1,536-well ultra-high-throughput siRNA screen to identify regulators of the Wnt/beta-catenin pathway by Chung, Namjin, Marine, Shane, Smith, Emily A, Liehr, Robert, Smith, S Todd, Locco, Louis, Hudak, Edward, Kreamer, Anthony, Rush, Alison, Roberts, Brian, Major, Michael B, Moon, Randall T, Arthur, William, Cleary, Michele, Strulovici, Berta, Ferrer, Marc

“…High-throughput siRNA screens are now widely used for identifying novel drug targets and mapping disease pathways. Despite their popularity, there remain…”
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6H-Benzo[c]chromen-6-one derivatives as selective ERbeta agonists by Sun, Wanying, Cama, Lovji D, Birzin, Elizabeth T, Warrier, Sudha, Locco, Louis, Mosley, Ralph, Hammond, Milton L, Rohrer, Susan P

“…A series of 6H-benzo[c]chromen-6-one and 6H-benzo[c]chromene derivatives were prepared, and the affinity and selectivity for ERalpha and ERbeta was measured…”
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Modeling directed design and biological evaluation of quinazolinones as non-peptidic growth hormone secretagogues by ZHIXIONG YE, YINGDUO GAO, LOCCO, L, PARMAR, R. M, CHAN, W. W.-S, SCHAEFFER, J. M, SMITH, R. G, PATCHETT, A. A, NARGUND, R. P, BAKSHI, R. K, CHEN, M.-H, ROHRER, S. P, FEIGHNER, S. D, PONG, S.-S, HOWARD, A. D, BLAKE, A, BIRZIN, E. T

“…Quinazolinone derivatives were synthesized and evaluated as non-peptidic growth hormone secretagogues. Modeling guided design of quinazolinone compound 21 led…”
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