Search Results - "Lobo, Jose M"
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Biosimilar medicines used for cancer therapy in Europe: a review
Published in Drug discovery today (01-01-2019)“…•Several new biosimilar medicines are continuously been introduced in the market.•Current oncologic biosimilars are epoetins, filgrastim, and monoclonal…”
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Skin Depigmenting Agents in Anti-Aging Cosmetics: A Medicinal Perspective on Emerging Ingredients
Published in Applied sciences (01-01-2022)“…Human skin aging results from intrinsic and extrinsic factors. Uneven pigmentation is one of the major changes of extrinsic aging. Many compounds have been…”
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Nucleic Acids Delivery Systems: A Challenge for Pharmaceutical Technologists
Published in Current drug metabolism (01-07-2015)“…Nucleic acids (NA) therapies, including therapy with genes, aptamers or antisense oligonucleotides, have been showing promising results, especially in the…”
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UV Filters: Challenges and Prospects
Published in Pharmaceuticals (Basel, Switzerland) (22-02-2022)“…The use of sunscreens is an established and recommended practice to protect skin from solar-induced damage. Around 30 UV filters can be used in sunscreen…”
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Marine Ingredients for Sensitive Skin: Market Overview
Published in Marine drugs (17-08-2021)“…Marine ingredients are a source of new chemical entities with biological action, which is the reason why they have gained relevance in the cosmetic industry…”
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In Vitro Evaluation of the Photoreactivity and Phototoxicity of Natural Polyphenol Antioxidants
Published in Molecules (Basel, Switzerland) (29-12-2021)“…Polyphenols are a large family of natural compounds widely used in cosmetic products due to their antioxidant and anti-inflammatory beneficial properties and…”
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BRAF mutation predicts sensitivity to MEK inhibition
Published in Nature (19-01-2006)“…The kinase pathway comprising RAS, RAF, mitogen-activated protein kinase kinase (MEK) and extracellular signal regulated kinase (ERK) is activated in most…”
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Sensitive skin: Active ingredients on the spotlight
Published in International journal of cosmetic science (01-02-2022)“…Objective Sensitive skin is characterized by self‐reported sensory perceptions in response to stimuli that should not provoke unpleasant sensations. Cosmetic…”
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Benefits of skin application of piceatannol—A minireview
Published in Australasian journal of dermatology (01-02-2023)“…The skin is the largest organ of the human body and has several functions such as barrier against external agents, the maintenance of temperature and…”
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Does the Vehicle Matter? Real-World Evidence on Adherence to Topical Treatment in Psoriasis
Published in Pharmaceutics (23-09-2021)“…The influence of the vehicle in topical treatment adherence remains to be elucidated. The aim of this study is to analyze the influence of the pharmaceutical…”
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Up-to-Date Overview of the Use of Natural Ingredients in Sunscreens
Published in Pharmaceuticals (Basel, Switzerland) (18-03-2022)“…The photoprotective skincare segment is in high demand to meet consumer concerns on UV-induced skin damage, with a recent trend towards sunscreen alternatives…”
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Recent Trends on UV filters
Published in Applied sciences (01-12-2022)“…UV filters are the shield ingredients of sunscreens against the negative effects of solar radiation. Since the discovery of the first UV filter, nearly 30…”
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Lipid nanoparticles for the delivery of biopharmaceuticals
Published in Current pharmaceutical biotechnology (01-01-2015)“…Biopharmaceuticals comprise therapeutic protein-based, nucleic acids and cell-based products. According to their therapeutic success, the clinical use of these…”
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Delivery systems for biopharmaceuticals. Part II: Liposomes, Micelles, Microemulsions and Dendrimers
Published in Current pharmaceutical biotechnology (01-01-2015)“…Biopharmaceuticals are a generation of drugs that include peptides, proteins, nucleic acids and cell products. According to their particular molecular…”
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Delivery Systems for Biopharmaceuticals. Part I: Nanoparticles and Microparticles
Published in Current pharmaceutical biotechnology (01-01-2015)“…Pharmaceutical biotechnology has been showing therapeutic success never achieved with conventional drug molecules. Therefore, biopharmaceutical products are…”
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Compressed matrix core tablet as a quick/slow dual-component delivery system containing ibuprofen
Published in AAPS PharmSciTech (01-01-2007)“…The purpose of the present research was to produce a quick/slow biphasic delivery system for ibuprofen. A dual-component tablet made of a sustained release…”
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On the viability of five probiotic strains when immobilised on various polymers
Published in International journal of dairy technology (01-02-2011)“…The viability of probiotic bacteria in six food-grade polymers, at two concentrations, was evaluated in order to predict their feasibility as materials for…”
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Management of skin adverse reactions in oncology
Published in Journal of Oncology Pharmacy Practice (01-10-2020)“…Chemo and targeted anticancer therapies present significant skin adverse reactions, which impair the patients’ quality of life. Cutaneous toxicities lead to…”
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Book Review Journal Article -
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Abstract 4682: Membrane protein expression and activity following inhibition of B-cell receptor-initiated signaling by WBMP-4, a therapeutic antibody for leukemia/lymphoma
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract The B-cell Receptor (BCR), comprising membrane Ig (mIg) and CD79a/b, controls normal signaling in B-cells, but dysregulation of this signaling is the…”
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Abstract P40: Therapeutic anti-B-cell Receptor antibody, WBMP-4, modulates malignant B-cell signaling and induces apoptosis
Published in Blood cancer discovery (04-03-2024)“…Abstract The B-cell Receptor (BCR), comprising CD79a/b and membrane Ig, initiates a driver pathway of cell survival and proliferation, and is a rational drug…”
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