Search Results - "Lobato, N S"
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The adipokine chemerin augments vascular reactivity to contractile stimuli via activation of the MEK-ERK1/2 pathway
Published in Life sciences (1973) (15-10-2012)“…Cytokines interfere with signaling pathways and mediators of vascular contraction. Endothelin-1 (ET-1) plays a major role on vascular dysfunction in conditions…”
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2
Mechanisms of endothelial dysfunction in obesity-associated hypertension
Published in Brazilian journal of medical and biological research (01-05-2012)“…Obesity is strongly associated with high blood pressure, dyslipidemia, and type 2 diabetes. These conditions synergistically increase the risk of…”
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Improvement of metabolic parameters and vascular function by metformin in obese non-diabetic rats
Published in Life sciences (1973) (30-01-2012)“…Metformin is an insulin sensitizing agent with beneficial effects in diabetic patients on glycemic levels and in the cardiovascular system. We examined whether…”
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Obesity induced by neonatal treatment with monosodium glutamate impairs microvascular reactivity in adult rats: Role of NO and prostanoids
Published in Nutrition, metabolism, and cardiovascular diseases (01-10-2011)“…Abstract Background and aim given that obesity is an independent risk factor for the development of cardiovascular diseases we decided to investigate the…”
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Vascular O-GlcNAcylation augments reactivity to constrictor stimuli by prolonging phosphorylated levels of the myosin light chain
Published in Brazilian journal of medical and biological research (01-10-2014)“…O-GlcNAcylation is a modification that alters the function of numerous proteins. We hypothesized that augmented O-GlcNAcylation levels enhance myosin light…”
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6
Endogenous testosterone increases leukocyte–endothelial cell interaction in spontaneously hypertensive rats
Published in Life sciences (1973) (15-05-2012)“…Inflammation may have an important role in the beginning and in the progress of cardiovascular diseases. Testosterone exerts important effects on vascular…”
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Chemerin/ChemR23 system plays crucial role upon vascular insulin signaling in db/db mice
Published in The FASEB journal (01-04-2016)“…Abstract only The adipokine chemerin and its receptor, chemokine‐like receptor 1 (ChemR23), influence major aspects of the metabolic syndrome, including…”
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