Search Results - "Loan, James"

Association between Computed Tomographic Biomarkers of Cerebral Small Vessel Diseases and Long‐Term Outcome after Spontaneous Intracerebral Hemorrhage by Rodrigues, Mark A., Samarasekera, Neshika, Lerpiniere, Christine, Perry, Luke A., Moullaali, Tom J., Loan, James, Wardlaw, Joanna M., Al‐Shahi Salman, Rustam

“…Objective A study was undertaken to assess whether cerebral small vessel disease (SVD) computed tomographic (CT) biomarkers are associated with long‐term…”
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Risks of recurrent stroke and all serious vascular events after spontaneous intracerebral haemorrhage: pooled analyses of two population-based studies by Li, Linxin, Poon, Michael T C, Samarasekera, Neshika E, Perry, Luke A, Moullaali, Tom J, Rodrigues, Mark A, Loan, James J M, Stephen, Jacqueline, Lerpiniere, Christine, Tuna, Maria A, Gutnikov, Sergei A, Kuker, Wilhelm, Silver, Louise E, Al-Shahi Salman, Rustam, Rothwell, Peter M

“…Patients with stroke due to spontaneous (non-traumatic) intracerebral haemorrhage (ICH) are at risk of recurrent ICH, ischaemic stroke, and other serious…”
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Secondary injury and inflammation after intracerebral haemorrhage: a systematic review and meta-analysis of molecular markers in patient brain tissue by Loan, James JM, Kirby, Caoimhe, Emelianova, Katherine, Dando, Owen R, Poon, Michael TC, Pimenova, Leisan, Hardingham, Giles E, McColl, Barry W, Klijn, Catharina JM, Al-Shahi Salman, Rustam, Schreuder, Floris HBM, Samarasekera, Neshika

“…BackgroundInflammatory responses to intracerebral haemorrhage (ICH) are potential therapeutic targets. We aimed to quantify molecular markers of inflammation…”
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Activation of Nrf2 to Optimise Immune Responses to Intracerebral Haemorrhage by Loan, James J M, Al-Shahi Salman, Rustam, McColl, Barry W, Hardingham, Giles E

“…Haemorrhage into the brain parenchyma can be devastating. This manifests as spontaneous intracerebral haemorrhage (ICH) after head trauma, and in the context…”
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Influence of preoperative embolisation on resection of brain arteriovenous malformations: cohort study by Lee, Seong Hoon, Loan, James JM, Downer, Jonathan, DuPlessis, Johannes, Keston, Peter, Wiggins, Anthony N., Fouyas, Ioannis, Sokol, Drahoslav

“…Purpose Preoperative endovascular embolisation is a widely used adjunct for the surgical treatment of brain arteriovenous malformations (AVMs). However,…”
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Medically induced hypertension, hypervolaemia and haemodilution for the treatment and prophylaxis of vasospasm following aneurysmal subarachnoid haemorrhage: systematic review by Loan, James J. M., Wiggins, Anthony N., Brennan, Paul M.

“…Purpose: Arterial vasospasm is a major cause of death and long-term disability following subarachnoid haemorrhage (SAH). The use of medically induced…”
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Ventriculoperitoneal shunt insertion in human immunodeficiency virus infected adults: a systematic review and meta-analysis by Loan, James J M, Poon, Michael T C, Tominey, Steven, Mankahla, Ncedile, Meintjes, Graeme, Fieggen, A Graham

“…Hydrocephalus is a common, life threatening complication of human immunodeficiency virus (HIV)-related central nervous system opportunistic infection which can…”
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Long-term survival and five year hospital resource usage following traumatic brain injury in Scotland from 1997 to 2015: A population-based retrospective cohort study by Loan, James J.M., Scott, Neil W., Jansen, Jan O.

“…•This population-based study included 25,319 patients with traumatic brain injury (TBI) over an 18 year follow-up period.•Control cases with head, but not…”
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Pre-operative obesity does not predict poorer symptom control and quality of life after lumbar disc surgery by Brennan, Paul M., Loan, James J. M., Watson, Neil, Bhatt, Pragnesh M., Bodkin, Peter Alwyn

“…Purpose: We aimed to determine whether there was a difference in post-operative symptomatic control and quality of life (QoL) between patients who were obese…”
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Investigation and management of serum sodium after subarachnoid haemorrhage (SaSH): a survey of practice in the United Kingdom and Republic of Ireland by Tominey, Steven, Baweja, Kirun, Woodfield, Julie, Chambers, Thomas J. G., Poon, Michael T. C., Wiggins, Anthony N., Brennan, Paul M., Loan, James J. M.

“…Hyponatraemia is a common complication of aneurysmal subarachnoid haemorrhage (SAH). We aimed to determine current neurosurgical practice for the…”
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Feasibility of comparing medical management and surgery (with neurosurgery or stereotactic radiosurgery) with medical management alone in people with symptomatic brain cavernoma - protocol for the Cavernomas: A Randomised Effectiveness (CARE) pilot trial by Loan, James J M, Bacon, Andrew, van Beijnum, Janneke, Bhatt, Pragnesh, Bjornson, Anna, Broomes, Nicole, Bullen, Alistair, Bulters, Diederik, Cahill, Julian, Chavredakis, Emmanuel, Colombo, Francesca, Danciut, Mihai, Digpal, Ronneil, Edwards, Richard J, Ferguson, Lucie, Forsyth, Laura, Fouyas, Ioannis, Ganesan, Vijeya, Grover, Patrick, Gurusinghe, Nihal, Hall, Peter S, Harkness, Kirsty, Harris, Lauren S, Hayton, Tom, Helmy, Adel, Holsgrove, Daniel, Hutchinson, Peter J, Israni, Anil, Kinsella, Elaine, Lewis, Steff, Majeed, Sohail, Mallucci, Conor, Mukerji, Nitin, Nair, Ramesh, Neilson, Aileen R, Papadopoulos, Marios C, Radatz, Matthias, Rossdeutsch, Alex, Raza-Knight, Saba, Stephen, Jacqueline, Stoddart, Andrew, Teo, Mario, Turner, Carole, Wade, Julia, Walsh, Daniel, White, David, White, Phil, Wildman, Jack, Wroe Wright, Oliver, Uff, Christopher, Ushewokunze, Shungu, Vindlacheruvu, Raghu, Kitchen, Neil, Al-Shahi Salman, Rustam

“…The top research priority for cavernoma, identified by a James Lind Alliance Priority setting partnership was 'Does treatment (with neurosurgery or…”
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Nrf2 activation in the human brain after stroke due to supratentorial intracerebral haemorrhage: a case–control study by Christopher, Edward, Loan, James J M, Samarasekera, Neshika, McDade, Karina, Rose, Jamie, Barrington, Jack, Hughes, Jeremy, Smith, Colin, Al-Shahi Salman, Rustam

“…AimsPharmacological activation of the antioxidative transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) improves outcomes in experimental…”
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Ventriculoperitoneal shunt insertion for hydrocephalus in human immunodeficiency virus-infected adults: a systematic review and meta-analysis protocol by Loan, James J M, Mankahla, Ncedile, Meintjes, Graeme, Fieggen, A Graham

“…Hydrocephalus is a recognised complication of human immunodeficiency virus (HIV)-related opportunistic infections. Symptomatic raised cerebrospinal fluid…”
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Association between circulating inflammatory biomarkers and functional outcome or perihaematomal oedema after ICH: a systematic review & meta-analysis by Kirby, Caoimhe, Barrington, Jack, Sondag, Lotte, Loan, James J M, Schreuder, Floris H B M, McColl, Barry W, Klijn, Catharina J M, Al-Shahi Salman, Rustam, Samarasekera, Neshika

“…Currently, there are no specific medical treatments for intracerebral haemorrhage (ICH), but the inflammatory response may provide a potential route to…”
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Association of baseline hematoma and edema volumes with one-year outcome and long-term survival after spontaneous intracerebral hemorrhage: A community-based inception cohort study by Gane, Angus B, Middleton, Laura, Moullaali, Tom James, Rodrigues, Mark A, Cunningham, Laura, Wardlaw, Joanna, Al-Shahi Salman, Rustam, Samarasekera, Neshika, Addison, Anne, Ahmad, Kate, Chandran, Siddharthan, Cook, Helen, Davenport, Richard, Derry, Chris, Dodds, Katrina, Duncan, Susan, Elder, Andrew, Fouyas, Ioannis, Gibson, Rod, Hewett, Russell, Hughes, Fiona, Hughes, Mark, Hunter, Neil, Ironside, James, Liaquat, Imran, Josephson, Colin, Kamat, Anant, Kealley, Susan, Kerr, Gillian, Keston, Peter, King, Matthew, Macdonald, Elizabeth, Mackay, Graham, Macleod, Donald, Maguire, Conor, Makin, Steven, Mathews, Ashok, Maxwell, Fiona, McClellan, Stuart, Morris, Zoe, Morse, Tim, Mumford, Colin, Myles, Lynn, Nimmo, Graham, Rannikmae, Kristiina, Rhodes, Jonathan, Shanmuganathan, Mano, Shekhar, Himanshu, Simms, Henry, Smith, Colin, Stone, Jon, Stuart, Joyce, Sudlow, Cathie, Summers, David, Taylor, Pat, Torgersen, Antonia, van Dijke, Margarethe, Walker, Robert, Weller, Belinda, Whiteley, William, Young, Wendy, Broadbent, Seona, Butler, Laura, Cantley, Patricia, Carter, Jonathan, Clegg, Gareth, Coull, Andrew, Crosswaite, Alastair, Dummer, Simon, Duncan, Fiona, Enright, Kate, Frier, Brian, Grant, David, Gray, Alasdair, Hart, Simon, Henderson, Robin, Jones, Michael, Masson, Moyra, McCallum, Lynn, Mead, Gillian, Morley, Wendy, Morrow, Billie, Morrow, Frank, Murphy, Ross, Ogundipe, Olayinka, Patel, Dilip, Reed, Matthew, Roberts, Geraint, Yordanov, Stanko, Bell, Nicola, Farquhar, Donald, Jackson, Katherine, Knox, Anne, McCafferty, Jon, Munang, Latana, Spence, Linda, Williams, Andrew, Fitzgerald, Alastair, Lange, Peter, McIntosh, Andrew

“…Background Hospital-based studies have reported variable associations between outcome after spontaneous intracerebral hemorrhage and peri-hematomal edema…”
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Association between circulating inflammatory biomarkers and functional outcome or perihaematomal oedema after ICH: a systematic review & meta-analysis by Kirby, Caoimhe, Barrington, Jack, Sondag, Lotte, Loan, James J.M., Schreuder, Floris H.B.M., McColl, Barry W., Klijn, Catharina J.M., Al-Shahi Salman, Rustam, Samarasekera, Neshika

“…Background Currently, there are no specific medical treatments for intracerebral haemorrhage (ICH), but the inflammatory response may provide a potential route…”
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Factors associated with cognitive impairment before intracerebral haemorrhage: community-based neuropathological study by Xiang, Yawen, Rodrigues, Mark A, Lerpiniere, Christine, Moullaali, Tom J, Loan, James J M, Wilkinson, Tim, Humphreys, Catherine A, Smith, Colin, Al-Shahi Salman, Rustam, Samarasekera, Neshika

“…Abstract Little is known about whether clinical, radiological or neuropathological features are associated with cognitive impairment before intracerebral…”
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Pre-operative warm up: Are we missing an opportunity to improve performance? A questionnaire by Loan, James J.M, Hughes, Mark A

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Brainstem abscess presenting with lateral gaze palsy in a healthy adolescent patient by Loan, James JM, Jamjoom, Aimun AB, Fouyas, Ioannis

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Prospective, multicentre study of screening, investigation and management of hyponatraemia after subarachnoid haemorrhage in the UK and Ireland by Tominey, Steven, Baweja, Kirun, Woodfield, Julie, Chambers, Thomas J G, Kundu, Simran S, Brennan, Paul M, Goitiandia, Sofia Weiss, Lyons, Adam, Freer-Smith, Charlotte, Baker, Olivia, O'Brien, David, McCandless, Conor, Roman, Elena, Teo, Mario, Meghrawi, Khadija, Mona, Taslima, Mohammed, Wail, Grufferty, David, Rajesh, Joel, Kaskun, Oleksandra, Sofela, Agbolahan, Toma, Arina, Tijare, Chinmay, Ahmad, Reddin, Poolovadoo, Yanish, Siddique, Amar Naqash, Othman, Lara, Giannakaki, Venetia, Mukerji, Nitin, Carr, Harry, Allison, Callum, Hughes, James T, Cheong, Jeremy, Piper, Rory, Lamb, Catherine, Bandyopadhyay, Soham, Honeyman, Susan Isabel, Rajashekar, Devika, Jung, Josephine, Cope, Jack, Mehta, Bhumi, Sanghvi, Hazel, McLean, Lily, Kalra, Neeraj, Anderson, Ian, Khan, Taufiq, Vyas, Neel, John, Anushka, Bin Jalal, Arif Hanafi, Ramali, Mohamed Rashad, Phuah, Yu Zhi, McSorley, Nathan, Hutton, Dana, Kouli, Omar, Chan, Huan Wee, Haley, Mark, Hollingworth, Milo, Frantzias, Joseph, Mohamed, Aisha Abubakar, Reyhani, Hadis, Sall, Jagbir Kaur, Belli, Antonio, Yakoub, Kamal, Lammy, Simon, Tang, Josephine, Maqsood, Raeesah, Kotikalapudi, Siddharth, Dasgupta, Debayan, Taqvi, Ahsan Ali, Southey, Charles, Loan, James, Tominey, Steven, Birt, Katie, Walters, Rachel, Nair, Sanjay Govind, Rooprai, Navleen, Radcliffe, Heather, Mohammed, Sophia, Galloway, Luke, Zaidi, Syed, Agarwal, Aastha, Lea, Alexander, Russell, Jordan, Denham, Katherine, Harris, Lauren, Sohrabi, Catrin, Dheden, Ngawang, Merola, Joseph, Tze Shan, Tiffany Ye, Merican, Diyanah, Vivian Pak, Hei Yi, Siah, Qi Zhuang, Chia, Wen Li, Hall, Samuel, Marwaha, Pavan Kaur, Robbin, Kiran, Millward, Christopher P, Foster, Kate, Patel, Parthik, Bahl, Sarthak

“…BackgroundHyponatraemia often occurs after subarachnoid haemorrhage (SAH). However, its clinical significance and optimal management are uncertain. We audited…”
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