Search Results - "LoPresto, Dora"
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Neural circuits and mechanisms involved in fear generalization: Implications for the pathophysiology and treatment of posttraumatic stress disorder
Published in Neuroscience and biobehavioral reviews (01-01-2016)“…Compelling evidence suggests that fear generalization (i.e. the transfer of fear from a particular stimulus to another one sharing similarities with the…”
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Ketamine accelerates fear extinction via mTORC1 signaling
Published in Neurobiology of disease (01-04-2017)“…Abstract Impaired fear extinction contributes to the persistence of post-traumatic stress disorder (PTSD), and can be utilized for the study of novel…”
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The association between serotonin transporter availability and the neural correlates of fear bradycardia
Published in Proceedings of the National Academy of Sciences - PNAS (17-12-2019)“…Susceptibility to stress-related psychopathology is associated with reduced expression of the serotonin transporter (5-HTT), particularly in combination with…”
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GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2017)“…GLYX-13 is a putative NMDA receptor modulator with glycine-site partial agonist properties that produces rapid antidepressant effects, but without the…”
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Using Yoda-1 to mimic laminar flow in vitro: A tool to simplify drug testing
Published in Biochemical pharmacology (01-10-2019)“…[Display omitted] The endothelium is an attractive drug target and an important site of adverse drug reactions. Endothelial dysfunction is strongly associated…”
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Acute inescapable stress alleviates fear extinction recall deficits caused by serotonin transporter abolishment
Published in Behavioural brain research (02-07-2018)“…Life stress increases risk for developing post-traumatic stress disorder (PTSD), and more prominently so in short-allele carriers of the serotonin transporter…”
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Improved Stress Control in Serotonin Transporter Knockout Rats: Involvement of the Prefrontal Cortex and Dorsal Raphe Nucleus
Published in ACS chemical neuroscience (15-07-2015)“…Variations in serotonin transporter (5-HTT) expression have been associated with altered sensitivity to stress. Since controllability is known to alter the…”
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