Search Results - "Lo Re, Daniele"

Long-term platinum-based drug accumulation in cancer-associated fibroblasts promotes colorectal cancer progression and resistance to therapy by Linares, Jenniffer, Sallent-Aragay, Anna, Badia-Ramentol, Jordi, Recort-Bascuas, Alba, Méndez, Ana, Manero-Rupérez, Noemí, Re, Daniele Lo, Rivas, Elisa I., Guiu, Marc, Zwick, Melissa, Iglesias, Mar, Martinez-Ciarpaglini, Carolina, Tarazona, Noelia, Varese, Monica, Hernando-Momblona, Xavier, Cañellas-Socias, Adrià, Orrillo, Mayra, Garrido, Marta, Saoudi, Nadia, Elez, Elena, Navarro, Pilar, Tabernero, Josep, Gomis, Roger R., Batlle, Eduard, Pisonero, Jorge, Cervantes, Andres, Montagut, Clara, Calon, Alexandre

“…A substantial proportion of cancer patients do not benefit from platinum-based chemotherapy (CT) due to the emergence of drug resistance. Here, we apply…”
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Anomer-Specific Recognition and Dynamics in a Fucose-Binding Lectin by Antonik, Paweł M, Volkov, Alexander N, Broder, Ursula N, Re, Daniele Lo, van Nuland, Nico A. J, Crowley, Peter B

“…Sugar binding by a cell surface ∼29 kDa lectin (RSL) from the bacterium Ralstonia solanacearum was characterized by NMR spectroscopy. The complexes formed with…”
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Synthesis of Pentahydroxylated Pyrrolizidines and Indolizidines by Tamayo, Juan A, Franco, Francisco, Lo Re, Daniele, Sánchez-Cantalejo, Fernando

“…1,3-Dipolar cycloaddition reaction of nitrone 7 and chemo-enzymatically obtained alkenediols 12 and 13 has been used in the synthesis of pentahydroxylated…”
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Maintenance Inhalers for Asthma and COPD in Spain by Muñoz, Xavier, Giner, Jordi, Sicras, Antoni, Re, Daniele Lo

“…This study aimed to describe the use of pressurized metered-dose inhalers (pMDIs) and dry powder inhalers (DPIs) in Spanish subjects in terms of…”
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Peptide–Platinum(IV) Conjugation Minimizes the Negative Impact of Current Anticancer Chemotherapy on Nonmalignant Cells by Linares, Jenniffer, Varese, Monica, Sallent-Aragay, Anna, Méndez, Ana, Palomo-Ponce, Sergio, Iglesias, Mar, Batlle, Eduard, Pisonero, Jorge, Montagut, Clara, Giralt, Ernest, Lo Re, Daniele, Calon, Alexandre

“…The relative success of platinum (Pt)-based chemotherapy comes at the cost of severe adverse side effects and is associated with a high risk of pro-oncogenic…”
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The Therapeutic Potential of Migrastatin-Core Analogs for the Treatment of Metastatic Cancer by Giralt, Ernest, Lo Re, Daniele

“…Tumor metastasis is a complex process in which cells detach from the primary tumor and colonize a distant organ. Metastasis is also the main process…”
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Comprehensive Observational Study in a Large Cohort of Asthma Patients after Adding LAMA to ICS/LABA by Plaza, Vicente, Domínguez-Ortega, Javier, González-Segura Alsina, Diego, Lo Re, Daniele, Sicras-Mainar, Antoni

“…Introduction: Adding LAMA to LABA/ICS is recommended to improve control in patients with persistent asthma. Methods: This observational, retrospective,…”
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Synthesis of Migrastatin Analogues as Inhibitors of Tumour Cell Migration: Exploring Structural Change in and on the Macrocyclic Ring by Lo Re, Daniele, Zhou, Ying, Mucha, Joanna, Jones, Leigh F., Leahy, Lorraine, Santocanale, Corrado, Krol, Magdalena, Murphy, Paul V.

“…Migrastatin and isomigrastatin analogues have been synthesised in order to contribute to structure–activity studies on tumour cell migration inhibitors. These…”
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Synthesis of an Orthogonally Protected Polyhydroxylated Cyclopentene from l-Sorbose by Lo Re, Daniele, Jones, Leigh, Giralt, Ernest, Murphy, Paul

“…The use of l‐sorbose in the synthesis of functionalized cyclopentene derivatives was accomplished. These cyclopentene derivatives are related to those found in…”
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Synthesis of Migrastatin Analogues as Inhibitors of Tumour Cell Migration: Exploring Structural Change in and on the Macrocyclic Ring by Lo Re, Daniele, Zhou, Ying, Mucha, Joanna, Jones, Leigh F., Leahy, Lorraine, Santocanale, Corrado, Krol, Magdalena, Murphy, Paul V.

“…Invited for the cover of this issue are Paul V. Murphy and co‐workers at the National University of Ireland Galway (NUI Galway) and Warsaw University. The…”
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Migrastatin analogues inhibit canine mammary cancer cell migration and invasion by Majchrzak, Kinga, Lo Re, Daniele, Gajewska, Małgorzata, Bulkowska, Małgorzata, Homa, Agata, Pawłowski, Karol, Motyl, Tomasz, Murphy, Paul V, Król, Magdalena

“…Cancer spread to other organs is the main cause of death of oncological patients. Migration of cancer cells from a primary tumour is the crucial step in the…”
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First total synthesis and absolute configuration of naturally occurring (−)-hyacinthacine A7 and its (−)-1-epi-isomer by Izquierdo, Isidoro, Plaza, María T., Tamayo, Juan A., Yáñez, Víctor, Lo Re, Daniele, Sánchez-Cantalejo, Fernando

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Total Synthesis of 3-O-Benzyl-1,3,5-tri-epi-calystegine B2 from L-Sorbose by Lo Re, Daniele, Franco, Francisco, Sánchez-Cantalejo, Fernando, Tamayo, Juan A.

“…The well known 2,3:4,6‐di‐O‐isopropylidene‐α‐L‐sorbofuranose (12) was chosen as starting material for the synthesis of…”
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Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones: Very strong correlation to pleurotin and thioredoxin reductase inhibition by Sweeney, Martin, Coyle, Robert, Kavanagh, Paul, Berezin, Andrey A., Lo Re, Daniele, Zissimou, Georgia A., Koutentis, Panayiotis A., Carty, Michael P., Aldabbagh, Fawaz

“…[Display omitted] The thioredoxin (Trx)–thioredoxin reductase (TrxR) system plays a key role in maintaining the cellular redox balance with Trx being…”
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Synthesis of Triazafluoranthenones via Silver(I)-Mediated Nonoxidative and Oxidative Intramolecular Palladium-Catalyzed Cyclizations by Koutentis, Panayiotis A, Loizou, Georgia, Lo Re, Daniele

“…Silver(I) fluoride (AgF)-mediated intramolecular nonoxidative and oxidative palladium-catalyzed cyclizations of 1,3-diphenyl- and…”
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Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase by Catto, Marco, Berezin, Andrey A., Lo Re, Daniele, Loizou, Georgia, Demetriades, Marina, De Stradis, Angelo, Campagna, Francesco, Koutentis, Panayiotis A., Carotti, Angelo

“…Alzheimer's disease (AD) onset and progression are associated with the dysregulation of multiple and complex physiological processes and a successful…”
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Synthesis, Biological Evaluation and Docking Studies of Casuarine Analogues: Effects of Structural Modifications at Ring B on Inhibitory Activity Towards Glucoamylase by Bonaccini, Claudia, Chioccioli, Matteo, Parmeggiani, Camilla, Cardona, Francesca, Lo Re, Daniele, Soldaini, Gianluca, Vogel, Pierre, Bello, Claudia, Goti, Andrea, Gratteri, Paola

“…We report the total synthesis of a series of pyrrolizidine analogues of casuarine (1) and their 6‐O‐α‐glucoside derivatives. The synthetic strategy is based on…”
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Synthesis of Migrastatin and its Macroketone Analogue and In Vivo FRAP Analysis of the Macroketone on E-Cadherin Dynamics by Lo Re, Daniele, Zhou, Ying, Nobis, Max, Anderson, Kurt I., Murphy, Paul V.

“…An efficient and scalable synthesis of a key acyclic intermediate used for the preparation of migrastatin and its macroketone analogue is described; Brown…”
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Cover Picture: Synthesis of Migrastatin Analogues as Inhibitors of Tumour Cell Migration: Exploring Structural Change in and on the Macrocyclic Ring (Chem. Eur. J. 50/2015) by Lo Re, Daniele, Zhou, Ying, Mucha, Joanna, Jones, Leigh F., Leahy, Lorraine, Santocanale, Corrado, Krol, Magdalena, Murphy, Paul V.

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Synthesis of (+)-1- epi-castanospermine from l-sorbose by Izquierdo, Isidoro, Tamayo, Juan A., Rodríguez, Miguel, Franco, Francisco, Lo Re, Daniele

“…Diastereoselective synthesis of 1- epi-castanospermine ( 2) from l-sorbose is described. The successful approach involved the use of 8-azido-2,8-dideoxy-α- l-…”
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