Search Results - "Lösche, Mathias"

Steering Molecular Dynamics Simulations of Membrane-Associated Proteins with Neutron Reflection Results by Treece, Bradley W, Heinrich, Frank, Ramanathan, Arvind, Lösche, Mathias

“…We present a novel method to incorporate structural results from surface-sensitive scattering, such as X-ray or neutron reflectometry, into molecular dynamics…”
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Association of Model Neurotransmitters with Lipid Bilayer Membranes by Josey, Brian P., Heinrich, Frank, Silin, Vitalii, Lösche, Mathias

“…Aimed at reproducing the results of electrophysiological studies of synaptic signal transduction, conventional models of neurotransmission are based on the…”
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Charge Effects Provide Ångström-Level Control of Lipid Bilayer Morphology on Titanium Dioxide Surfaces by Michalak, Dennis J, Lösche, Mathias, Hoogerheide, David P

“…Interfaces between molecular organic architectures and oxidic substrates are a central feature of biosensors and applications of biomimetics in science and…”
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A New Lipid Anchor for Sparsely Tethered Bilayer Lipid Membranes by Heinrich, Frank, Ng, Tiffany, Vanderah, David J, Shekhar, Prabhanshu, Mihailescu, Mihaela, Nanda, Hirsh, Lösche, Mathias

“…Mixed self-assembled monolayers (SAMs) of β-mercaptoethanol and the new synthetic lipid 1,2-dipalmityl-3-[ω-mercaptonona(ethylene oxide)] glycerol (FC16) were…”
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Information gain from isotopic contrast variation in neutron reflectometry on protein–membrane complex structures by Heinrich, Frank, Kienzle, Paul A., Hoogerheide, David P., Lösche, Mathias

“…A framework is applied to quantify information gain from neutron or X‐ray reflectometry experiments [Treece, Kienzle, Hoogerheide, Majkrzak, Lösche & Heinrich…”
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Structural and biophysical properties of farnesylated KRas interacting with the chaperone SmgGDS-558 by Michalak, Dennis J., Unger, Bethany, Lorimer, Ellen, Grishaev, Alexander, Williams, Carol L., Heinrich, Frank, Lösche, Mathias

“…KRas is a small GTPase and membrane-bound signaling protein. Newly synthesized KRas is post-translationally modified with a membrane-anchoring prenyl group…”
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Membrane Anchoring of Hck Kinase via the Intrinsically Disordered SH4-U and Length Scale Associated with Subcellular Localization by Pond, Matthew P., Eells, Rebecca, Treece, Bradley W., Heinrich, Frank, Lösche, Mathias, Roux, Benoît

“…Src family kinases (SFKs) are a group of nonreceptor tyrosine kinases that are characterized by their involvement in critical signal transduction pathways…”
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Structure and Properties of Tethered Bilayer Lipid Membranes with Unsaturated Anchor Molecules by Budvytyte, Rima, Valincius, Gintaras, Niaura, Gediminas, Voiciuk, Vladislava, Mickevicius, Mindaugas, Chapman, Hilary, Goh, Haw-Zan, Shekhar, Prabhanshu, Heinrich, Frank, Shenoy, Siddharth, Lösche, Mathias, Vanderah, David J

“…The self-assembled monolayers (SAMs) of new lipidic anchor molecule HC18 [Z-20-(Z-octadec-9-enyloxy)-3,6,9,12,15,18,22-heptaoxatetracont-31-ene-1-thiol] and…”
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Membrane Binding of HIV-1 Matrix Protein: Dependence on Bilayer Composition and Protein Lipidation by Barros, Marilia, Heinrich, Frank, Datta, Siddhartha A K, Rein, Alan, Karageorgos, Ioannis, Nanda, Hirsh, Lösche, Mathias

“…By assembling in a protein lattice on the host's plasma membrane, the retroviral Gag polyprotein triggers formation of the viral protein/membrane shell. The MA…”
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Myr-Arf1 conformational flexibility at the membrane surface sheds light on the interactions with ArfGAP ASAP1 by Zhang, Yue, Soubias, Olivier, Pant, Shashank, Heinrich, Frank, Vogel, Alexander, Li, Jess, Li, Yifei, Clifton, Luke A., Daum, Sebastian, Bacia, Kirsten, Huster, Daniel, Randazzo, Paul A., Lösche, Mathias, Tajkhorshid, Emad, Byrd, R. Andrew

“…ADP-ribosylation factor 1 (Arf1) interacts with multiple cellular partners and membranes to regulate intracellular traffic, organelle structure and actin…”
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The cytosolic domain of T-cell receptor ζ associates with membranes in a dynamic equilibrium and deeply penetrates the bilayer by Zimmermann, Kerstin, Eells, Rebecca, Heinrich, Frank, Rintoul, Stefanie, Josey, Brian, Shekhar, Prabhanshu, Lösche, Mathias, Stern, Lawrence J.

“…Interactions between lipid bilayers and the membrane-proximal regions of membrane-associated proteins play important roles in regulating membrane protein…”
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Interaction of the Neurotransmitter, Neuropeptide Y, with Phospholipid Membranes:  Film Balance and Fluorescence Microscopy Studies by Dyck, Martina, Lösche, Mathias

“…The association of neuropeptide Y (NPY) with air−water interfaces and with phospholipid monolayers on water subphases and on physiological buffer has been…”
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Membrane association of the PTEN tumor suppressor: molecular details of the protein-membrane complex from SPR binding studies and neutron reflection by Shenoy, Siddharth, Shekhar, Prabhanshu, Heinrich, Frank, Daou, Marie-Claire, Gericke, Arne, Ross, Alonzo H, Lösche, Mathias

“…The structure and function of the PTEN phosphatase is investigated by studying its membrane affinity and localization on in-plane fluid, thermally disordered…”
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Interaction of the Neurotransmitter, Neuropeptide Y, with Phospholipid Membranes:  Infrared Spectroscopic Characterization at the Air/Water Interface by Dyck, Martina, Kerth, Andreas, Blume, Alfred, Lösche, Mathias

“…The association of neuropeptide Y (NPY) at the air/water interface and with phospholipid monolayers on water as subphase has been investigated using external…”
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A unified nomenclature and amino acid numbering for human PTEN by Pulido, Rafael, Baker, Suzanne J, Barata, Joao T, Carracedo, Arkaitz, Cid, Victor J, Chin-Sang, Ian D, Davé, Vrushank, den Hertog, Jeroen, Devreotes, Peter, Eickholt, Britta J, Eng, Charis, Furnari, Frank B, Georgescu, Maria-Magdalena, Gericke, Arne, Hopkins, Benjamin, Jiang, Xeujun, Lee, Seung-Rock, Lösche, Mathias, Malaney, Prerna, Matias-Guiu, Xavier, Molina, María, Pandolfi, Pier Paolo, Parsons, Ramon, Pinton, Paolo, Rivas, Carmen, Rocha, Rafael M, Rodríguez, Manuel S, Ross, Alonzo H, Serrano, Manuel, Stambolic, Vuk, Stiles, Bangyan, Suzuki, Akira, Tan, Seong-Seng, Tonks, Nicholas K, Trotman, Lloyd C, Wolff, Nicolas, Woscholski, Rudiger, Wu, Hong, Leslie, Nicholas R

“…The tumor suppressor PTEN is a major brake for cell transformation, mainly due to its phosphatidylinositol 3,4,5-trisphosphate [PI(3,4,5)P3] phosphatase…”
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Enzyme Activity to Augment the Characterization of Tethered Bilayer Membranes by Valincius, Gintaras, McGillivray, Duncan J, Febo-Ayala, Wilma, Vanderah, David J, Kasianowicz, John J, Lösche, Mathias

“…The rate of Ca2+-triggered phospholipase A2 (PLA2) degradation of tethered bilayer membranes (tBLMs), composed of a synthetic lipid, β-mercaptoethanol, and…”
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Detailed Structure of Molecularly Thin Polyelectrolyte Multilayer Films on Solid Substrates as Revealed by Neutron Reflectometry by Lösche, Mathias, Schmitt, Johannes, Decher, Gero, Bouwman, Wim G, Kjaer, Kristian

“…Using neutron reflectometry we have resolvedto high resolutionthe internal structure of self-assembled polyelectrolyte multilayer films and have developed a…”
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Effect of synthetic aβ peptide oligomers and fluorinated solvents on Kv1.3 channel properties and membrane conductance by Lioudyno, Maria I, Broccio, Matteo, Sokolov, Yuri, Rasool, Suhail, Wu, Jessica, Alkire, Michael T, Liu, Virginia, Kozak, J Ashot, Dennison, Philip R, Glabe, Charles G, Lösche, Mathias, Hall, James E

“…The impact of synthetic amyloid β (1-42) (Aβ(1-42)) oligomers on biophysical properties of voltage-gated potassium channels Kv 1.3 and lipid bilayer membranes…”
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Anomalous x-ray reflectivity characterization of ion distribution at biomimetic membranes by Vaknin, David, Krüger, Peter, Lösche, Mathias

“…Anomalous x-ray reflectivity measurements provides detailed information on ion binding to biomembrane surfaces. Using a monochromatic beam tuned to various…”
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A bacteriophage endolysin that eliminates intracellular streptococci by Shen, Yang, Barros, Marilia, Vennemann, Tarek, Gallagher, D Travis, Yin, Yizhou, Linden, Sara B, Heselpoth, Ryan D, Spencer, Dennis J, Donovan, David M, Moult, John, Fischetti, Vincent A, Heinrich, Frank, Lösche, Mathias, Nelson, Daniel C

“…PlyC, a bacteriophage-encoded endolysin, lyses Streptococcus pyogenes (Spy) on contact. Here, we demonstrate that PlyC is a potent agent for controlling…”
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