Search Results - "Löffler, M."

A DNA‐Programmed Liposome Fusion Cascade by Löffler, Philipp M. G., Ries, Oliver, Rabe, Alexander, Okholm, Anders H., Thomsen, Rasmus P., Kjems, Jørgen, Vogel, Stefan

“…Chemically engineered and functionalized nanoscale compartments are used in bottom‐up synthetic biology to construct compartmentalized chemical processes…”
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Opportunistic osteoporosis screening in multi-detector CT images via local classification of textures by Valentinitsch, A., Trebeschi, S., Kaesmacher, J., Lorenz, C., Löffler, M. T., Zimmer, C., Baum, T., Kirschke, J. S.

“…Summary Our study proposed an automatic pipeline for opportunistic osteoporosis screening using 3D texture features and regional vBMD using multi-detector CT…”
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Targeting SARS-CoV-2 spike protein by stapled hACE2 peptides by Maas, Marijn N, Hintzen, Jordi C J, Löffler, Philipp M G, Mecinović, Jasmin

“…SARS-CoV-2 Spike protein RBD interacts with the hACE2 receptor to initiate cell entry and infection. We set out to develop lactam-based i,i + 4 stapled hACE2…”
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Clinical, pathological and genetic features of follicular lymphoma grade 3A: a joint analysis of the German low-grade and high-grade lymphoma study groups GLSG and DSHNHL by Koch, K., Hoster, E., Ziepert, M., Unterhalt, M., Ott, G., Rosenwald, A., Hansmann, M.L., Bernd, W., Stein, H., Pöschel, V., Dreyling, M., Trümper, L., Löffler, M., Schmitz, N., Hiddemann, W., Pfreundschuh, M., Klapper, W.

“…Histologically, follicular lymphoma (FL) grades 1, 2 and 3A are composed of two distinct cell types, centroblasts and centrocytes. FL grade 3B is composed only…”
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Programmable RNA Loading of Extracellular Vesicles with Toehold-Release Purification by Malle, Mette Galsgaard, Song, Ping, Löffler, Philipp M. G., Kalisi, Nazmie, Yan, Yan, Valero, Julián, Vogel, Stefan, Kjems, Jørgen

“…Synthetic nanoparticles as lipid nanoparticles (LNPs) are widely used as drug delivery vesicles. However, they hold several drawbacks, including low…”
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Orotate (orotic acid): An essential and versatile molecule by Löffler, M., Carrey, E.A., Zameitat, E.

“…Orotate (OA) is well-known as a precursor in biosynthesis of pyrimidines; in mammals it is released from the mitochondrial dihydroorotate dehydrogenase (DHODH)…”
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X-ray-based quantitative osteoporosis imaging at the spine by Löffler, M.T., Sollmann, N., Mei, K., Valentinitsch, A., Noël, P.B., Kirschke, J.S., Baum, T.

“…Osteoporosis is a metabolic bone disease with a high prevalence that affects the population worldwide, particularly the elderly. It is often due to fractures…”
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Single-particle combinatorial multiplexed liposome fusion mediated by DNA by Malle, Mette Galsgaard, Löffler, Philipp M. G., Bohr, Søren S.-R., Sletfjerding, Magnus Berg, Risgaard, Nikolaj Alexander, Jensen, Simon Bo, Zhang, Min, Hedegård, Per, Vogel, Stefan, Hatzakis, Nikos S.

“…Combinatorial high-throughput methodologies are central for both screening and discovery in synthetic biochemistry and biomedical sciences. They are, however,…”
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Epidemiology and reporting of osteoporotic vertebral fractures in patients with long-term hospital records based on routine clinical CT imaging by Löffler, M. T., Kallweit, M., Niederreiter, E., Baum, T., Makowski, M. R., Zimmer, C., Kirschke, J. S.

“…Summary Osteoporotic vertebral fractures signify an increased risk of future fractures and mortality and can manifest the diagnosis of osteoporosis. We…”
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Phase Relations in the CaO-Nd2O3-Al2O3 System in Application for Rare Earth Recycling by Ilatovskaia, M., Lonski, O., Löffler, M., Blenau, L., Charitos, A., Fabrichnaya, O.

“…Phase relations in the CaO-Al 2 O 3 -Nd 2 O 3 system were investigated in the temperature range between 1330°C and 1600°C using equilibration technique…”
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Experimental Investigation and Thermodynamic Modeling of the Li2O–Al2O3 System by de Abreu, D. A., Löffler, M., Kriegel, M. J., Fabrichnaya, O.

“…In the present work, phase equilibria in the Li 2 O–Al 2 O 3 system were experimentally studied and calorimetric measurements were performed. Based on obtained…”
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Maize ARGOS1 (ZAR1) transgenic alleles increase hybrid maize yield by Guo, Mei, Rupe, Mary A, Wei, Jun, Winkler, Chris, Goncalves-Butruille, Marymar, Weers, Ben P, Cerwick, Sharon F, Dieter, Jo Ann, Duncan, Keith E, Howard, Richard J, Hou, Zhenglin, Löffler, Carlos M, Cooper, Mark, Simmons, Carl R

“…A single transgene ARGOS1 positively impacts yield of field-grown hybrid maize. Two predominant alleles from elite hybrid breeding germplasm differed in…”
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Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids by TODORIC, J, LÖFFLER, M, HUBER, J, BILBAN, M, REIMERS, M, KADL, A, ZEYDA, M, WALDHÄUSL, W, STULNIG, T. M

“…Inflammatory alterations in white adipose tissue appear to underlie complications of obesity including diabetes mellitus. Polyunsaturated fatty acids (PUFA),…”
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New perspectives on the roles of pyrimidines in the central nervous system by Löffler, M., Carrey, E. A., Zameitat, E.

“…Since 1956, when exogenous uridine and cytidine were found to be necessary for the maintenance of perfused rat brain function, the co-existence of de novo…”
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Novel biomarker SARIFA in colorectal cancer: highly prognostic, not genetically driven and histologic indicator of a distinct tumor biology by Reitsam, Nic G., Grozdanov, Veselin, Löffler, Chiara M. L., Muti, Hannah S., Grosser, Bianca, Kather, Jakob N., Märkl, Bruno

“…SARIFA (Stroma AReactive Invasion Front Areas) has recently emerged as a promising histopathological biomarker for colon and gastric cancer. To elucidate the…”
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Prevention of high-fat diet-induced adipose tissue remodeling in obese diabetic mice by n-3 polyunsaturated fatty acids by Huber, J, Loffler, M, Bilban, M, Reimers, M, Kadl, A, Todoric, J, Zeyda, M, Geyeregger, R, Schreiner, M, Weichhart, T

“…Objective: Obesity is associated with reduced insulin sensitivity and extensive reorganization of adipose tissue. As polyunsaturated fatty acids (PUFA) appear…”
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Stable Vesicles Composed of Monocarboxylic or Dicarboxylic Fatty Acids and Trimethylammonium Amphiphiles by Caschera, F, de la Serna, J. Bernardino, Löffler, P. M. G, Rasmussen, T. E, Hanczyc, M. M, Bagatolli, L. A, Monnard, P.-A

“…The self-assembly of cationic and anionic amphiphile mixtures into vesicles in aqueous media was studied using two different systems: (i) decanoic acid and…”
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Quantitative analysis of backscattered electron (BSE) contrast using low voltage scanning electron microscopy (LVSEM) and its application to Al0.22Ga0.78N/GaN layers by Garitagoitia Cid, A., Rosenkranz, R., Löffler, M., Clausner, A., Standke, Y., Zschech, E.

“…•A method for quantification of backscattered electron (BSE) contrast is proposed.•Sub-layers Al0.22Ga0.78N/GaN are identified using low primary beam energy in…”
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A prospectively randomized trial carried out by the German Hodgkin Study Group (GHSG) for elderly patients with advanced Hodgkin's disease comparing BEACOPP baseline and COPP-ABVD (study HD9elderly) by Ballova, V., Rüffer, J.-U., Haverkamp, H., Pfistner, B., Müller-Hermelink, H. K., Dühmke, E., Worst, P., Wilhelmy, M., Naumann, R., Hentrich, M., Eich, H. T., Josting, A., Löffler, M., Diehl, V., Engert, A.

“…In contrast to younger patients, the prognosis of elderly patients with advanced Hodgkin's disease (HD) has not improved substantially over the last 20 years…”
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Lipidated Polyaza Crown Ethers as Membrane Anchors for DNA-Controlled Content Mixing between Liposomes by Löffler, Philipp M. G., Hansen, Anders Højgaard, Ries, Oliver, Jakobsen, Ulla, Rabe, Alexander, Sørensen, Kristian T., Glud, Kasper, Vogel, Stefan

“…The ability to manipulate and fuse nano-compartmentalized volumes addresses a demand for spatiotemporal control in the field of synthetic biology, for example…”
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