Search Results - "Löffler, Ivonne"

Pharmacological Targeting of the RAGE-NFκB Signalling Axis Impedes Monocyte Activation under Diabetic Conditions through the Repression of SHP-2 Tyrosine Phosphatase Function by Dorenkamp, Marc, Nasiry, Madina, Semo, Dilvin, Koch, Sybille, Löffler, Ivonne, Wolf, Gunter, Reinecke, Holger, Godfrey, Rinesh

“…Monocytes play a vital role in the development of cardiovascular diseases. Type 2 diabetes mellitus (T2DM) is a major CVD risk factor, and T2DM-induced…”
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Polar Compounds Dominate in Vitro Effects of Sediment Extracts by Lübcke-von Varel, Urte, Machala, Miroslav, Ciganek, Miroslav, Neca, Jiri, Pencikova, Katerina, Palkova, Lenka, Vondracek, Jan, Löffler, Ivonne, Streck, Georg, Reifferscheid, Georg, Flückiger-Isler, Sini, Weiss, Jana M, Lamoree, Marja, Brack, Werner

“…Sediment extracts from three polluted sites of the river Elbe basin were fractionated using a novel online fractionation procedure. Resulting fractions were…”
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Identification and quantitative confirmation of dinitropyrenes and 3-nitrobenzanthrone as major mutagens in contaminated sediments by Lübcke-von Varel, Urte, Bataineh, Mahmoud, Lohrmann, Stefanie, Löffler, Ivonne, Schulze, Tobias, Flückiger-Isler, Sini, Neca, Jiri, Machala, Miroslav, Brack, Werner

“…Polar fractions of a sediment extract of the industrial area of Bitterfeld, Germany, have been subjected for effect-directed identification of mutagens using…”
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Role of cAMP in the promotion of colorectal cancer cell growth by prostaglandin E2 by Löffler, Ivonne, Grün, Michael, Böhmer, Frank D, Rubio, Ignacio

“…Prostaglandin E2 (PGE2), a product of the cyclooxygenase (COX) reaction, stimulates the growth of colonic epithelial cells. It is inferred that the abrogation…”
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Prostaglandin E2 differentially modulates proinflammatory/prodestructive effects of TNF-alpha on synovial fibroblasts via specific E prostanoid receptors/cAMP by Kunisch, Elke, Jansen, Anne, Kojima, Fumiaki, Löffler, Ivonne, Kapoor, Mohit, Kawai, Shinichi, Rubio, Ignacio, Crofford, Leslie J, Kinne, Raimund W

“…The present study investigated the influence of PGE(2), E prostanoid (EP) receptors, and their signaling pathways on matrix metalloproteinase (MMP)-1 and IL-6…”
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TGF-β and fibrosis in different organs — molecular pathway imprints by Pohlers, Dirk, Brenmoehl, Julia, Löffler, Ivonne, Müller, Cornelia K., Leipner, Carola, Schultze-Mosgau, Stefan, Stallmach, Andreas, Kinne, Raimund W., Wolf, Gunter

“…The action of transforming-growth-factor (TGF)-β following inflammatory responses is characterized by increased production of extracellular matrix (ECM)…”
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Hyperglycaemia-induced methylglyoxal accumulation potentiates VEGF resistance of diabetic monocytes through the aberrant activation of tyrosine phosphatase SHP-2/SRC kinase signalling axis by Dorenkamp, Marc, Müller, Jörg P., Shanmuganathan, Kallipatti Sanjith, Schulten, Henny, Müller, Nicolle, Löffler, Ivonne, Müller, Ulrich A., Wolf, Gunter, Böhmer, Frank-D., Godfrey, Rinesh, Waltenberger, Johannes

“…Diabetes mellitus (DM) is a major cardiovascular risk factor contributing to cardiovascular complications by inducing vascular cell dysfunction. Monocyte…”
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Cardiovascular risk due to diabetes mellitus in patients with chronic kidney disease—prospective data from the German Chronic Kidney Disease cohort by Ruhe, Johannes, Nadal, Jennifer, Bärthlein, Barbara, Meiselbach, Heike, Schultheiss, Ulla T, Kotsis, Fruzsina, Stockmann, Helena, Krane, Vera, Sommerer, Claudia, Löffler, Ivonne, Saritas, Turgay, Kielstein, Jan T, Sitter, Thomas, Schneider, Markus P, Schmid, Matthias, Wanner, Christoph, Eckardt, Kai-Uwe, Wolf, Gunter, Busch, Martin

“…Background Diabetes mellitus (DM) and chronic kidney disease (CKD) are well-known cardiovascular and mortality risk factors. To what extent they act in an…”
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Prostaglandin E2 Differentially Modulates Proinflammatory/Prodestructive Effects of TNF-α on Synovial Fibroblasts via Specific E Prostanoid Receptors/cAMP1 by Kunisch, Elke, Jansen, Anne, Kojima, Fumiaki, Löffler, Ivonne, Kapoor, Mohit, Kawai, Shinichi, Rubio, Ignacio, Crofford, Leslie J., Kinne, Raimund W.

“…The present study investigated the influence of PGE 2 , E prostanoid (EP) receptors, and their signaling pathways on matrix metalloproteinase (MMP)-1 and IL-6…”
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Hyperglycemia-Induced Deregulation of Thioredoxin System Contributes to the Functional Impairment of Monocytes Resulting in Compromised Collateral Remodelling in Diabetes Mellitus by Godfrey, Rinesh, Schulten, Henny M, Kallipatti Shanmuganathan, Sanjith, Ringel, Alessa, Loffler, Ivonne, Miiller, Nicolle, Wolf, Gunter, Miller, Ulrich A, Bohmer, Frank D, Waltenberger, Johannes

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31 - Hyperglycemia-Induced Deregulation of Thioredoxin System Contributes to the Functional Impairment of Monocytes Resulting in Compromised Collateral Remodelling in Diabetes Mellitus by Godfrey, Rinesh, Schulten, Henny M, Kallipatti Shanmuganathan, Sanjith, Ringel, Alessa, Loffler, Ivonne, Miiller, Nicolle, Wolf, Gunter, Miller, Ulrich A, Bohmer, Frank D, Waltenberger, Johannes

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Prostaglandin E2 Differentially Modulates Proinflammatory/Prodestructive Effects of TNF-{alpha} on Synovial Fibroblasts via Specific E Prostanoid Receptors/cAMP by Kunisch, Elke, Jansen, Anne, Kojima, Fumiaki, Loffler, Ivonne, Kapoor, Mohit, Kawai, Shinichi, Rubio, Ignacio, Crofford, Leslie J, Kinne, Raimund W

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