Search Results - "Lo, Y.M."

The Long and Short of Circulating Cell-Free DNA and the Ins and Outs of Molecular Diagnostics by Jiang, Peiyong, Lo, Y.M. Dennis

“…The discovery of cell-free tumor and fetal DNA molecules in the plasma of cancer patients and pregnant women, respectively, has opened up exciting…”
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Conventional and Novel Applications of Edible Mushrooms in Today's Food Industry by Moon, B, Lo, Y.M

“…For centuries, mushrooms have been used as a part of the human diet and also as medicinal ingredients because they are a good source of nutrients and have…”
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The Biology of Cell-free DNA Fragmentation and the Roles of DNASE1, DNASE1L3, and DFFB by Han, Diana S.C., Ni, Meng, Chan, Rebecca W.Y., Chan, Vicken W.H., Lui, Kathy O., Chiu, Rossa W.K., Lo, Y.M. Dennis

“…Cell-free DNA (cf.DNA) is a powerful noninvasive biomarker for cancer and prenatal testing, and it circulates in plasma as short fragments. To elucidate the…”
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Analysis of Plasma Epstein–Barr Virus DNA to Screen for Nasopharyngeal Cancer by Chan, K.C. Allen, Woo, John K.S, King, Ann, Zee, Benny C.Y, Lam, W.K. Jacky, Chan, Stephen L, Chu, Sam W.I, Mak, Constance, Tse, Irene O.L, Leung, Samantha Y.M, Chan, Gloria, Hui, Edwin P, Ma, Brigette B.Y, Chiu, Rossa W.K, Leung, Sing-Fai, van Hasselt, Andrew C, Chan, Anthony T.C, Lo, Y.M. Dennis

“…Circulating Epstein–Barr virus DNA was measured in 20,174 asymptomatic participants in Hong Kong; 34 of 309 with positive results had nasopharyngeal cancer…”
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Antitumor Activity of Nivolumab in Recurrent and Metastatic Nasopharyngeal Carcinoma: An International, Multicenter Study of the Mayo Clinic Phase 2 Consortium (NCI-9742) by Ma, Brigette B Y, Lim, Wan-Teck, Goh, Boon-Cher, Hui, Edwin P, Lo, Kwok-Wai, Pettinger, Adam, Foster, Nathan R, Riess, Jonathan W, Agulnik, Mark, Chang, Alex Y C, Chopra, Akhil, Kish, Julie A, Chung, Christine H, Adkins, Douglas R, Cullen, Kevin J, Gitlitz, Barbara J, Lim, Dean W, To, Ka-Fai, Chan, K C Allen, Lo, Y M Dennis, King, Ann D, Erlichman, Charles, Yin, Jun, Costello, Brian A, Chan, Anthony T C

“…Purpose This multinational study evaluated the antitumor activity of nivolumab in nasopharyngeal carcinoma (NPC). Tumor and plasma-based biomarkers were…”
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Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin by Sun, Kun, Jiang, Peiyong, Cheng, Suk Hang, Cheng, Timothy H T, Wong, John, Wong, Vincent W S, Ng, Simon S M, Ma, Brigette B Y, Leung, Tak Y, Chan, Stephen L, Mok, Tony S K, Lai, Paul B S, Chan, Henry L Y, Sun, Hao, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis

“…Cell-free DNA (cfDNA) in human plasma is a class of biomarkers with many current and potential future diagnostic applications. Recent studies have shown that…”
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Analysis of Plasma Epstein-Barr Virus DNA in Nasopharyngeal Cancer After Chemoradiation to Identify High-Risk Patients for Adjuvant Chemotherapy: A Randomized Controlled Trial by Chan, Anthony T C, Hui, Edwin P, Ngan, Roger K C, Tung, Stewart Y, Cheng, Ashley C K, Ng, Wai T, Lee, Victor H F, Ma, Brigette B Y, Cheng, Hoi C, Wong, Frank C S, Loong, Herbert H F, Tong, Macy, Poon, Darren M C, Ahuja, Anil T, King, Ann D, Wang, Ki, Mo, Frankie, Zee, Benny C Y, Chan, K C Allen, Lo, Y M Dennis

“…Purpose The contribution of adjuvant chemotherapy after chemoradiation therapy (CRT) in nasopharyngeal cancer (NPC) remains controversial. Plasma Epstein-Barr…”
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Simulation of near-shore solitary wave mechanics by an incompressible SPH method by Y.M. Lo, Edmond, Shao, Songdong

“…An incompressible smoothed particle hydrodynamics (SPH) method together with a large eddy simulation (LES) approach is used to simulate the near-shore solitary…”
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Cell-Free DNA Fragmentomics in Liquid Biopsy by Ding, Spencer C, Lo, Y M Dennis

“…Cell-free DNA (cfDNA) in bodily fluids has rapidly transformed the development of noninvasive prenatal testing, cancer liquid biopsy, and transplantation…”
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Single-Molecule Detection of Epidermal Growth Factor Receptor Mutations in Plasma by Microfluidics Digital PCR in Non - Small Cell Lung Cancer Patients by YUNG, Tony K. F, CHAN, K. C. Allen, MOK, Tony S. K, TONG, Joanna, TO, Ka-Fai, LO, Y. M. Dennis

“…We aim to develop a digital PCR-based method for the quantitative detection of the two common epidermal growth factor receptor (EGFR) mutations (in-frame…”
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Recovery of nicotine-free proteins from tobacco leaves using phosphate buffer system under controlled conditions by Fu, H., Machado, P.A., Hahm, T.S., Kratochvil, R.J., Wei, C.I., Lo, Y.M.

“…Establishment of an effective, high-throughput processing system to recover protein from tobacco with no nicotine contamination is essential and vital to the…”
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Plasma Epstein-Barr Viral Deoxyribonucleic Acid Quantitation Complements Tumor-Node-Metastasis Staging Prognostication in Nasopharyngeal Carcinoma by Leung, Sing-fai, Zee, Benny, Ma, Brigette B, Hui, Edwin P, Mo, Frankie, Lai, Maria, Chan, K C Allen, Chan, Lisa Y S, Kwan, Wing-hong, Lo, Y M Dennis, Chan, Anthony T C

“…To evaluate the effect of combining circulating Epstein-Barr viral (EBV) DNA load data with TNM staging data in pretherapy prognostication of nasopharyngeal…”
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Noninvasive Approaches to Prenatal Diagnosis of Hemoglobinopathies Using Fetal DNA in Maternal Plasma by Lo, Y.M. Dennis, DM, DPhil, Chiu, Rossa W.K., MBBS, PhD

“…Fetal DNA is present in the plasma of pregnant women and can be used for noninvasive prenatal diagnosis. Early work had focused on the detection of paternally…”
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Recent Advances in Fetal Nucleic Acids in Maternal Plasma by Lo, Y.M. Dennis

“…The discovery of cell-free fetal DNA in maternal plasma in 1997 has opened up new possibilities for noninvasive prenatal diagnosis. Circulating fetal DNA…”
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Assessment of Trans Fatty Acids Content in Popular Western-Style Products in China by Fu, H, Yang, L, Yuan, H, Rao, P, Lo, Y.M

“…To date, the published information on trans fatty acids (TFAs) in food products in China remains scarce and of questionable accuracy. Systematic approaches to…”
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Genome-wide expression analysis using microarray identified complex signaling pathways modulated by hypoxia in nasopharyngeal carcinoma by Sung, Fion L, Hui, Edwin P, Tao, Qian, Li, Hongyu, Tsui, Nancy B.Y, Dennis Lo, Y.M, Ma, Brigette B.Y, To, Ka F, Harris, Adrian L, Chan, Anthony T.C

“…Abstract Previously, we showed that hypoxia-inducible factor (HIF)-1α, HIF-2α, carbonic anhydrase IX (CA IX), and vascular endothelial growth factor (VEGF)…”
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Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients by Lee, Nelson, Allen Chan, K.C., Hui, David S., Ng, Enders K.O., Wu, Alan, Chiu, Rossa W.K., Wong, Vincent W.S., Chan, Paul K.S., Wong, K.T., Wong, Eric, Cockram, C.S., Tam, John S., Sung, Joseph J.Y., Lo, Y.M. Dennis

“…The effect of corticosteroid treatment on the viral load of Severe Acute Respiratory Syndrome (SARS) patients is unknown. To compare the plasma SARS-CoV RNA…”
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Effects of nucleases on cell-free extrachromosomal circular DNA by Sin, Sarah Tk, Deng, Jiaen, Ji, Lu, Yukawa, Masashi, Chan, Rebecca Wy, Volpi, Stefano, Vaglio, Augusto, Fenaroli, Paride, Bocca, Paola, Cheng, Suk Hang, Wong, Danny Kl, Lui, Kathy O, Jiang, Peiyong, Chan, K C Allen, Chiu, Rossa Wk, Lo, Y M Dennis

“…Cell-free extrachromosomal circular DNA (eccDNA) as a distinct topological form from linear DNA has recently gained increasing research interest, with possible…”
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Persistent Aberrations in Circulating DNA Integrity after Radiotherapy Are Associated with Poor Prognosis in Nasopharyngeal Carcinoma Patients by CHAN, K. C. Allen, LEUNG, Sing-Fai, YEUNG, Sze-Wan, CHAN, Anthony T. C, LO, Y. M. Dennis

“…Purpose: Aberrations of circulating nucleic acid integrity have been observed in cancer patients. However, the clinical significance of such changes has not…”
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Assessing urban growth dynamics of major Southeast Asian cities using night-time light data by Kamarajugedda, Shankar Acharya, Mandapaka, Pradeep V, Lo, Edmond Y.M

“…This study analysed urban growth patterns for 15 Southeast Asian cities using remotely sensed night-time light data from 1992 to 2012. We extracted three urban…”
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