Search Results - "Lo, Y. Y."

Noninvasive Prenatal Diagnosis of Congenital Adrenal Hyperplasia Using Cell-Free Fetal DNA in Maternal Plasma by New, Maria I, Tong, Yu K, Yuen, Tony, Jiang, Peiyong, Pina, Christian, Chan, K. C. Allen, Khattab, Ahmed, Liao, Gary J. W, Yau, Mabel, Kim, Se-Min, Chiu, Rossa W. K, Sun, Li, Zaidi, Mone, Lo, Y. M

“…Context: Congenital adrenal hyperplasia (CAH) is an autosomal recessive condition that arises from mutations in CYP21A2 gene, which encodes for the…”
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Circulating biomarkers in the diagnosis and management of hepatocellular carcinoma by Johnson, Philip, Zhou, Qing, Dao, Doan Y, Lo, Y. M. Dennis

“…Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal causes of cancer-related death worldwide. The treatment of HCC remains challenging and…”
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Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies by Lo, Y M Dennis, Han, Diana S C, Jiang, Peiyong, Chiu, Rossa W K

“…Liquid biopsies that analyze cell-free DNA in blood plasma are used for noninvasive prenatal testing, oncology, and monitoring of organ transplant recipients…”
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The Nexus of cfDNA and Nuclease Biology by Han, Diana S.C., Lo, Y.M. Dennis

“…Cell-free DNA (cfDNA) is a widely used noninvasive biomarker for diagnosis and prognosis of multiple disease states. Emerging evidence suggests that cfDNA…”
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Emission trading and carbon market performance in Shenzhen, China by Cong, Ren, Lo, Alex Y.

“…•We assessed the market performance of Shenzhen’s emission trading scheme.•Trading records were used to estimate the degree of volatility and return…”
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The Long and Short of Circulating Cell-Free DNA and the Ins and Outs of Molecular Diagnostics by Jiang, Peiyong, Lo, Y.M. Dennis

“…The discovery of cell-free tumor and fetal DNA molecules in the plasma of cancer patients and pregnant women, respectively, has opened up exciting…”
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Identification and characterization of extrachromosomal circular DNA in maternal plasma by Sin, Sarah T. K., Jiang, Peiyong, Deng, Jiaen, Ji, Lu, Cheng, Suk Hang, Dutta, Anindya, Leung, Tak Y., Chan, K. C. Allen, Chiu, Rossa W. K., Lo, Y. M. Dennis

“…We explored the presence of extrachromosomal circular DNA (eccDNA) in the plasma of pregnant women. Through sequencing following either restriction enzyme or…”
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Single-step deposition of high-mobility graphene at reduced temperatures by Boyd, D.A., Lin, W.-H., Hsu, C.-C., Teague, M.L., Chen, C.-C., Lo, Y.-Y., Chan, W.-Y., Su, W.-B., Cheng, T.-C., Chang, C.-S., Wu, C.-I., Yeh, N.-C.

“…Current methods of chemical vapour deposition (CVD) of graphene on copper are complicated by multiple processing steps and by high temperatures required in…”
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Cell-free DNA for Colorectal Cancer Screening by Lo, Y.M. Dennis

“…This editorial describes the science behind a study of a noninvasive blood-based assay of cell-free DNA to screen for colorectal cancer in an average-risk…”
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Optimal heat stress metric for modelling heat-related mortality varies from country to country by Eunice Lo, Y T, Mitchell, Dann M, Buzan, Jonathan R, Zscheischler, Jakob, Schneider, Rochelle, Mistry, Malcolm N, Kyselý, Jan, Lavigne, Éric, da Silva, Susana Pereira, Royé, Dominic, Urban, Aleš, Armstrong, Ben, Gasparrini, Antonio, Vicedo-Cabrera, Ana M

“…Combined heat and humidity is frequently described as the main driver of human heat-related mortality, more so than dry-bulb temperature alone. While based on…”
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Repeated multi-qubit readout and feedback with a mixed-species trapped-ion register by Negnevitsky, V., Marinelli, M., Mehta, K. K., Lo, H.-Y., Flühmann, C., Home, J. P.

“…Quantum error correction is essential for realizing the full potential of large-scale quantum information processing devices 1 , 2 . Fundamental to its…”
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Diabetic Retinopathy: Pathophysiology and Treatments by Wang, Wei, Lo, Amy C Y

“…Diabetic retinopathy (DR) is the most common complication of diabetes mellitus (DM). It has long been recognized as a microvascular disease. The diagnosis of…”
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Quantum harmonic oscillator state synthesis by reservoir engineering by Kienzler, D., Lo, H.-Y., Keitch, B., de Clercq, L., Leupold, F., Lindenfelser, F., Marinelli, M., Negnevitsky, V., Home, J. P.

“…The robust generation of quantum states in the presence of decoherence is a primary challenge for explorations of quantum mechanics at larger scales. Using the…”
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Enhanced cancer detection from cell-free DNA by Jiang, Peiyong, Lo, Y. M. Dennis

“…A new assay for cell-free DNA fragmentation improves prediction of gene expression in liquid biopsies…”
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Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing by Sun, Kun, Jiang, Peiyong, Wong, Ada I. C., Cheng, Yvonne K. Y., Cheng, Suk Hang, Zhang, Haiqiang, Chan, K. C. Allen, Leung, Tak Y., Chiu, Rossa W. K., Lo, Y. M. Dennis

“…Cell-free DNA in human plasma is nonrandomly fragmented and reflects genomewide nucleosomal organization. Previous studies had demonstrated tissue-specific…”
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Optimization of ultrasonic-assisted extraction of pomegranate (Punica granatum L.) seed oil by Tian, Yuting, Xu, Zhenbo, Zheng, Baodong, Martin Lo, Y.

“…► Ultrasonic extraction gave the highest yield among the treatments investigated. ► Petroleum ether was the most practical and economical extraction solvent. ►…”
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Reconceptualizing green infrastructure for climate change adaptation: Barriers to adoption and drivers for uptake by spatial planners by Matthews, Tony, Lo, Alex Y., Byrne, Jason A.

“…•The paper defines the concept of green infrastructure within the context of climate adaptation.•Green infrastructure uptake is subject to biophysical and…”
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Discovery of Cell-Free Fetal DNA in Maternal Blood and Development of Noninvasive Prenatal Testing: 2022 Lasker-DeBakey Clinical Medical Research Award by Lo, Y. M. Dennis

“…In this Viewpoint, 2022 Lasker-DeBakey Clinical Medical Research Award winner Y. M. Dennis Lo discusses his discovery and application of cell-free fetal DNA…”
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Microfluidics Digital PCR Reveals a Higher than Expected Fraction of Fetal DNA in Maternal Plasma by Lun, Fiona M. F, Chiu, Rossa W. K, Allen Chan, K. C, Yeung Leung, Tak, Kin Lau, Tze, Dennis Lo, Y. M

“…The precise measurement of cell-free fetal DNA in maternal plasma facilitates noninvasive prenatal diagnosis of fetal chromosomal aneuploidies and other…”
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Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients by Jiang, Peiyong, Chan, Carol W. M., Chan, K. C. Allen, Cheng, Suk Hang, Wong, John, Wong, Vincent Wai-Sun, Wong, Grace L. H., Chan, Stephen L., Mok, Tony S. K., Chan, Henry L. Y., Lai, Paul B. S., Chiu, Rossa W. K., Lo, Y. M. Dennis

“…Significance We used massively parallel sequencing to study the size profiles of plasma DNA samples at single-base resolution and in a genome-wide manner. We…”
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