Search Results - "Lo, Y. M. D."

Plasma Epstein–Barr viral DNA load at midpoint of radiotherapy course predicts outcome in advanced-stage nasopharyngeal carcinoma by Leung, S.F., Chan, K.C.A., Ma, B.B., Hui, E.P., Mo, F., Chow, K.C.K., Leung, L., Chu, K.W., Zee, B., Lo, Y.M.D., Chan, A.T.C.

“…To test the hypothesis that prognostication of treatment outcome is feasible by biomarker response at midcourse of chemoradiotherapy (CRT)/radiotherapy (RT),…”
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Circulating tumour-derived nucleic acids in cancer patients: potential applications as tumour markers by CHAN, K. C. A, LO, Y. M. D

“…Tumour-associated changes have been observed in the circulating nucleic acids of cancer patients and have been proposed to be useful for the detection and…”
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Cancer genome scanning in plasma: detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing by Chan, K C Allen, Jiang, Peiyong, Zheng, Yama W L, Liao, Gary J W, Sun, Hao, Wong, John, Siu, Shing Shun N, Chan, Wing C, Chan, Stephen L, Chan, Anthony T C, Lai, Paul B S, Chiu, Rossa W K, Lo, Y M D

“…Tumor-derived DNA can be found in the plasma of cancer patients. In this study, we explored the use of shotgun massively parallel sequencing (MPS) of plasma…”
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What do we need to obtain high quality circulating tumor DNA (ctDNA) for routine diagnostic test in oncology? – Considerations on pre-analytical aspects by the IFCC workgroup cfDNA by Danesi, R., Lo, Y.M.D., Oellerich, M., Beck, J., Galbiati, S., Re, M. Del, Lianidou, E., Neumaier, M., van Schaik, R.H.N.

“…•Preanalytical variables influence the quality and quantity of isolated cfDNA.•This paper compares preanalytical aspects published for cfDNA analysis.•Blood…”
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Integrating postradiotherapy plasma Epstein–Barr virus DNA and TNM stage for risk stratification of nasopharyngeal carcinoma to adjuvant therapy by Hui, E.P., Li, W.F., Ma, B.B., Lam, W.K.J., Chan, K.C.A., Mo, F., Ai, Q.Y.H., King, A.D., Wong, C.H., Guo, R., Poon, D.M.C., Tong, M., Li, L., Lau, T.K.H., Wong, K.C.W., Lam, D.C.M., Lo, Y.M.D., Ma, J., Chan, A.T.C.

“…After curative radiotherapy (RT) or chemoradiation (CRT), there is no validated tool to accurately identify patients for adjuvant therapy in nasopharyngeal…”
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Detection of circulating fetal nucleic acids: a review of methods and applications by Hung, E C W, Chiu, R W K, Lo, Y M D

“…The discovery of cell-free circulating fetal nucleic acids in maternal plasma has opened up new possibilities in non-invasive prenatal diagnosis. The rapid…”
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Quantitation of circulating DNA in the serum of breast cancer patients by real-time PCR by GAL, S, FIDLER, C, LO, Y. M. D, TAYLOR, M, HAN, C, MOORE, J, HARRIS, A. L, WAINSCOAT, J. S

“…The purpose of this study was to quantify the level of serum DNA in different groups of primary breast cancer patients and in healthy controls using real-time…”
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Improved risk stratification of nasopharyngeal cancer by targeted sequencing of Epstein–Barr virus DNA in post-treatment plasma by Chan, D.C.T., Lam, W.K.J., Hui, E.P., Ma, B.B.Y., Chan, C.M.L., Lee, V.C.T., Cheng, S.H., Gai, W., Jiang, P., Wong, K.C.W., Mo, F., Zee, B., King, A.D., Le, Q.T., Chan, A.T.C., Chan, K.C.A., Lo, Y.M.D.

“…Quantitative measurement of plasma Epstein–Barr virus (EBV) DNA by real-time PCR at the end of primary treatment is a robust prognostic marker for…”
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Complementary roles of MRI and endoscopic examination in the early detection of nasopharyngeal carcinoma by King, A.D., Woo, J.K.S., Ai, Q.Y., Chan, J.S.M., Lam, W.K.J., Tse, I.O.L., Bhatia, K.S., Zee, B.C.Y., Hui, E.P., Ma, B.B.Y., Chiu, R.W.K., van Hasselt, A.C., Chan, A.T.C., Lo, Y.M.D., Chan, K.C.A.

“…Early-stage nasopharyngeal carcinoma (NPC) evades detection when the primary tumor is hidden from view on endoscopic examination. Therefore, in a prospective…”
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Noninvasive prenatal detection of fetal chromosomal aneuploidies by maternal plasma nucleic acid analysis: a review of the current state of the art by Lo, YMD

“…Fetal nucleic acids in maternal plasma have opened up new possibilities for noninvasive prenatal diagnosis of chromosomal aneuploidies. One approach is based…”
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Early Detection of Cancer: Evaluation of MR Imaging Grading Systems in Patients with Suspected Nasopharyngeal Carcinoma by King, A D, Woo, J K S, Ai, Q-Y, Mo, F K F, So, T Y, Lam, W K J, Tse, I O L, Vlantis, A C, Yip, K W N, Hui, E P, Ma, B B Y, Chiu, R W K, Chan, A T C, Lo, Y M D, Chan, K C A

“…We evaluated modifications to our contrast-enhanced MR imaging grading system for symptomatic patients with suspected nasopharyngeal carcinoma, aimed at…”
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Detection of minority nucleic acid populations by PCR by Lo, Y M

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SARS diagnosis, monitoring and prognostication by SARS-coronavirus RNA detection by Lo, Y M D

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Non-invasive prenatal diagnosis by Lo, Y M, Wainscoat, J S, Fleming, K A

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Systematic micro-array based identification of placental mRNA in maternal plasma: towards non-invasive prenatal gene expression profiling by Tsui, N B Y, Chim, S S C, Chiu, R W K, Lau, T K, Ng, E K O, Leung, T N, Tong, Y K, Chan, K C A, Lo, Y M D

“…The data also suggest that there are no significant differences in the liberation and clearance of the studied transcripts when compared with hPL, which would…”
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Detection of NPM-ALK DNA rearrangement in CD30 positive anaplastic large cell lymphoma by Waggott, W, Lo, Y M, Bastard, C, Gatter, K C, Leroux, D, Mason, D Y, Boultwood, J, Wainscoat, J S

“…CD30 positive anaplastic large cell lymphoma (ALCL) is a type of non-Hodgkin's lymphoma associated with a specific chromosome translocation between chromosomes…”
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Prenatal determination of fetal rhesus D status by DNA amplification of peripheral blood of rhesus-negative mothers by Lo, Y M, Bowell, P J, Selinger, M, Mackenzie, I Z, Chamberlain, P, Gillmer, M D, Elliott, P, Pratt, G, Littlewood, T J, Fleming, K A

“…We have developed a sensitive PCR-based assay for the RhD gene and used it to detect circulating fetal cells from RhD-positive fetuses from peripheral blood of…”
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Proteomic profiling in SARS: diagnostic and prognostic applications by Poon, T C W, Pang, R T K, Chan, K C A, Lee, N L S, Chiu, R W K, Tong, Y K, Chim, S S C, Ngai, S M, Sung, J J Y, Lo, Y M D

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Evidence of circulating donor genetic material in bone allotransplantation by Partsalis, T, Chan, L, Hurworth, M, Willers, C, Pavlos, N, Kumta, N, Wood, D, Xu, J, Kumta, S, Lo, Y, Zheng, M

“…Musculoskeletal allotransplantion is the most common form of human tissue transplantation. Unlike solid organ transplants, bone allotransplants undergo…”
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Strategies for the detection of autosomal fetal DNA sequence from maternal peripheral blood by Lo, Y M, Fleming, K A, Wainscoat, J S

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