Search Results - "Lo, Winnie"

Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories by Taylor, Renea A., Fraser, Michael, Livingstone, Julie, Espiritu, Shadrielle Melijah G., Thorne, Heather, Huang, Vincent, Lo, Winnie, Shiah, Yu-Jia, Yamaguchi, Takafumi N., Sliwinski, Ania, Horsburgh, Sheri, Meng, Alice, Heisler, Lawrence E., Yu, Nancy, Yousif, Fouad, Papargiris, Melissa, Lawrence, Mitchell G., Timms, Lee, Murphy, Declan G., Frydenberg, Mark, Hopkins, Julia F., Bolton, Damien, Clouston, David, McPherson, John D., van der Kwast, Theodorus, Boutros, Paul C., Risbridger, Gail P., Bristow, Robert G.

“…Germline mutations in the BRCA2 tumour suppressor are associated with both an increased lifetime risk of developing prostate cancer (PCa) and increased risk of…”
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A Prostate Cancer “ Nimbosus ”: Genomic Instability and SChLAP1 Dysregulation Underpin Aggression of Intraductal and Cribriform Subpathologies by Chua, Melvin L.K, Lo, Winnie, Pintilie, Melania, Murgic, Jure, Lalonde, Emilie, Bhandari, Vinayak, Mahamud, Osman, Gopalan, Anuradha, Kweldam, Charlotte F, van Leenders, Geert J.L.H, Verhoef, Esther I, Hoogland, Agnes Marije, Livingstone, Julie, Berlin, Alejandro, Dal Pra, Alan, Meng, Alice, Zhang, Junyan, Orain, Michèle, Picard, Valérie, Hovington, Hélène, Bergeron, Alain, Lacombe, Louis, Fradet, Yves, Têtu, Bernard, Reuter, Victor E, Fleshner, Neil, Fraser, Michael, Boutros, Paul C, van der Kwast, Theodorus H, Bristow, Robert G

“…Abstract Background Intraductal carcinoma (IDC) and cribriform architecture (CA) represent unfavorable subpathologies in localized prostate cancer. We recently…”
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AI-doscopist: a real-time deep-learning-based algorithm for localising polyps in colonoscopy videos with edge computing devices by Poon, Carmen C. Y., Jiang, Yuqi, Zhang, Ruikai, Lo, Winnie W. Y., Cheung, Maggie S. H., Yu, Ruoxi, Zheng, Yali, Wong, John C. T., Liu, Qing, Wong, Sunny H., Mak, Tony W. C., Lau, James Y. W.

“…We have designed a deep-learning model, an “Artificial Intelligent Endoscopist (a.k.a. AI-doscopist)”, to localise colonic neoplasia during colonoscopy. This…”
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Congenital midline spinal hamartoma in an infant with DICER1 syndrome: A case report by Hammad, Rawan, Lo, Winnie, Chen, Haiying, Shroff, Manohar, Malkin, David, Villani, Anita, Denburg, Avram

“…Congenital spinal hamartomas are rare benign tumors. They are mostly seen in infants and are typically asymptomatic at presentation. Spinal hamartomas have not…”
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Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma by Lo, Winnie W., Wunder, Jay S., Dickson, Brendan C., Campbell, Veronica, McGovern, Karen, Alman, Benjamin A., Andrulis, Irene L.

“…BACKGROUND During development, the Hedgehog pathway plays important roles regulating the proliferation and differentiation of chondrocytes, providing a…”
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mTOR Inhibitors as a New Therapeutic Strategy in Treatment Resistant Epilepsy in Hemimegalencephaly: A Case Report by Xu, Qi, Uliel-Sibony, Shimrit, Dunham, Christopher, Sarnat, Harvey, Flores-Sarnat, Laura, Brunga, Ledia, Davidson, Scott, Lo, Winnie, Shlien, Adam, Connolly, Mary, Boelman, Cyrus, Datta, Anita

“…Hemimegalencephaly is a hamartomatous malformation of one hemisphere. Functional hemispherectomy, the definitive treatment, is associated with significant…”
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The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations by Villani, Anita, Davidson, Scott, Kanwar, Nisha, Lo, Winnie W, Li, Yisu, Cohen-Gogo, Sarah, Fuligni, Fabio, Edward, Lisa-Monique, Light, Nicholas, Layeghifard, Mehdi, Harripaul, Ricardo, Waldman, Larissa, Gallinger, Bailey, Comitani, Federico, Brunga, Ledia, Hayes, Reid, Anderson, Nathaniel D, Ramani, Arun K, Yuki, Kyoko E, Blay, Sasha, Johnstone, Brittney, Inglese, Cara, Hammad, Rawan, Goudie, Catherine, Shuen, Andrew, Wasserman, Jonathan D, Venier, Rosemarie E, Eliou, Marianne, Lorenti, Miranda, Ryan, Carol Ann, Braga, Michael, Gloven-Brown, Meagan, Han, Jianan, Montero, Maria, Spatare, Famida, Whitlock, James A, Scherer, Stephen W, Chun, Kathy, Somerville, Martin J, Hawkins, Cynthia, Abdelhaleem, Mohamed, Ramaswamy, Vijay, Somers, Gino R, Kyriakopoulou, Lianna, Hitzler, Johann, Shago, Mary, Morgenstern, Daniel A, Tabori, Uri, Meyn, Stephen, Irwin, Meredith S, Malkin, David, Shlien, Adam

“…We conducted integrative somatic-germline analyses by deeply sequencing 864 cancer-associated genes, complete genomes and transcriptomes for 300 mostly…”
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Inadequate energy and protein intake, underweight and malnutrition are associated with in‐hospital mortality among COVID‐19 rehabilitation patients during the omicron outbreak in Hong Kong by Ting, Terry Ho Yan, Lo, Tiffany Hoi Man, Lo, Winnie Wing Tung, Ding, Qi, Yuk, Daniel Ka Lok, Hui, Elsie, Tang, Maria Wing Sze

“…Objective Malnourished COVID‐19 patients were prone to higher mortality and longer length of stay (LOS). This study aims to investigate the malnutrition risk…”
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Aberrant Hedgehog Signaling and Clinical Outcome in Osteosarcoma by Lo, Winnie W., Pinnaduwage, Dushanthi, Gokgoz, Nalan, Wunder, Jay S., Andrulis, Irene L.

“…Despite the importance of Hedgehog signaling in bone development, the relationship between Hedgehog pathway expression and osteosarcoma clinical…”
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The RESPCCT Study: Community-led Development of a Person-Centered Instrument to Measure Health Equity in Perinatal Services by Vedam, Saraswathi, Stoll, Kathrin, Tarasoff, Lesley, Phillips-Beck, Wanda, Lo, Winnie, MacDonald, Kate, Metellus, Ariane, Rost, Michael, Scott, Muriel, Hodge, Karen, Korchinski, Mo, van der Pijl, Marit, Alonso, Cristina, Clark, Esther, Tatum, Ali, Olson, Rachel, Xie, Kathy, Decker, Mary, Wenzel, Karolina, Roine, Alexandra, Hall, Wendy

“…While Canadian maternal mortality rates suggest widespread access to high-quality care, perinatal health care outcomes and care experiences among pregnant…”
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Empirical estimation of price and income elasticities of air cargo demand: The case of Hong Kong by Lo, Winnie Wai Ling, Wan, Yulai, Zhang, Anming

“…•We estimate the aggregated demand and supply functions of airfreight in Hong Kong.•Air cargo transport demand in Hong Kong is inelastic in price.•Air cargo…”
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DIGITAL IMAGE PROCESSING by LO, WINNIE Y., PUCHALSKI, SARAH M.

“…Image processing or digital image manipulation is one of the greatest advantages of digital radiography (DR). Preprocessing depends on the modality and…”
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333 Targeting the apical intracellular checkpoint CISH unleashes T cell neoantigen reactivity and effector program by Palmer, Douglas, Webber, Beau, Patel, Yogin, Johnson, Matthew, Kariya, Christine, Lahr, Walker, Parkhurst, Maria, Gartner, Jared, Prickett, Todd, Lowery, Frank, Kishton, Rigel, Gurusamy, Devikala, Franco, Zulmarie, Vodnala, Suman, Diers, Miechaleen, Wolf, Natalie, Slipek, Nicholas, McKenna, David, Sumstad, Darin, Viney, Lydia, Henley, Tom, Bürckstümmer, Tilmann, Baker, Oliver, Hu, Ying, Yan, Chunhua, Meerzaman, Daoud, Padhan, Kartik, Lo, Winnie, Malekzadeh, Parisa, Jia, Li, Deniger, Drew, Patel, Shashank, Robbins, Paul, Scott McIvor, R, Choudhry, Modassir, Rosenberg, Steven, Moriarity, Branden, Restifo, Nicholas

“…BackgroundNeoantigen-specific T cells isolated from tumors have shown promise clinically but fail to consistently elicit durable tumor regression. Expression…”
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The effect of body mass index on the outcome of pregnancy in women with recurrent miscarriage by Lo, Winnie, Rai, Raj, Hameed, Aisha, Brailsford, Susan R, Al-Ghamdi, Ahlam A, Regan, Lesley

“…Maternal obesity is associated with menstrual disorders, infertility and sporadic miscarriages. Recurrent miscarriage (RM) affects at least 1% of couples…”
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Restrictive orbital myofibroblastic sarcoma in a cat – Cross‐sectional imaging (MRI & CT) appearance, treatment, and outcome by Thomasy, Sara M., Cissell, Derek D., Arzi, Boaz, Vilches‐Moure, Jose G., Lo, Winnie Y., Wisner, Erik R., Dubielzig, Richard R., Maggs, David J.

“…A 16‐year‐old spayed female cat was evaluated for lagophthalmos and chronic exposure keratitis in both eyes. Ophthalmic examination revealed upper and lower…”
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Multiscale image processing and antiscatter grids in digital radiography by Lo, W. Y, Hornof, W. J, Zwingenberger, A. L, Robertson, I. D

“…Scatter radiation is a source of noise and results in decreased signal-to-noise ratio and thus decreased image quality in digital radiography. We determined…”
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Abstract 2486: Tumor hypoxia induces DNA repair vulnerabilities through contextual loss of heterozygosity by Mahamud, Osman, Chua, Melvin, Lo, Winnie, Zafarana, Gaetano, Bristow, Robert

“…Abstract Introduction: Intratumoural hypoxia leads to decreased expression in DNA damage response (DDR) and repair pathways. Given the ‘two-hit’ model for loss…”
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USING THE DELPHI METHOD TO VALIDATE INDICATORS OF RESPECTFUL MATERNITY CARE FOR HIGH RESOURCE COUNTRIES by Clark, Esther, Vedam, Saraswathi, Mclean, Alison, Stoll, Kathrin, Lo, Winnie, Hall, Wendy A

“…Consistent measurement of respectful maternity care (RMC) is lacking. This Delphi study assessed consensus about indicators of RMC. A multidisciplinary panel…”
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Better Together by Barn, Prabjit, Rideout, Karen L., Lo, Winnie, Josey, Dennis, Vint, Zackari, Sha, Cindy, Hamilton, Clayon, Hoens, Alison M., Shellington, Erin M., Joshi, Phalgun B., Carlsten, Christopher

“…Partnering with patients and community stakeholders to identify, design, undertake, and evaluate research is increasingly common. We describe our experience…”
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Better Together: Launching and Nurturing a Community Stakeholder Committee to Enhance Care and Research for Asthma and COPD by Barn, Prabjit, Rideout, Karen L, Lo, Winnie, Josey, Dennis, Vint, Zackari, Sha, Cindy, Hamilton, Clayon, Hoens, Alison M, Shellington, Erin M, Joshi, Phalgun B, Carlsten, Christopher

“…Partnering with patients and community stakeholders to identify, design, undertake, and evaluate research is increasingly common. We describe our experience…”
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