Search Results - "Lo, S. R."

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  1. 1

    Rho-mediated signaling promotes BRAF inhibitor resistance in de-differentiated melanoma cells by Misek, S. A., Appleton, K. M., Dexheimer, T. S., Lisabeth, E. M., Lo, R. S., Larsen, S. D., Gallo, K. A., Neubig, R. R.

    Published in Oncogene (13-02-2020)
    “…Over half of cutaneous melanoma tumors have BRAF V600E/K mutations. Acquired resistance to BRAF inhibitors (BRAFi) remains a major hurdle in attaining durable…”
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    Journal Article
  2. 2

    Undrained Behavior of Sand-Fines Mixtures and Their State Parameter by Rahman, Md. Mizanur, Lo, S. R

    “…AbstractThe influence of fines on the undrained behavior of sand was investigated experimentally over a range of fines content and effective mean stress. The…”
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  3. 3

    On equivalent granular void ratio and steady state behaviour of loose sand with fines by Rahman, M. M, Lo, S. R, Gnanendran, C. T

    Published in Canadian geotechnical journal (01-10-2008)
    “…Void ratio has traditionally been used as a state variable for predicting the liquefaction behaviour of soils under the critical state soil mechanics…”
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  4. 4

    Predicting the Onset of Static Liquefaction of Loose Sand with Fines by Md. Mizanur, Rahman, Lo, S. R

    “…AbstractLoose sandy soil subject to undrained shearing manifests deviatoric strain softening, and such a behavior has been referred to as collapse, static…”
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  5. 5

    Linkage between static and cyclic liquefaction of loose sand with a range of fines contents by BAKI, Md. A. L, RAHMAN, M. M, LO, S. R, GNANENDRAN, C. T

    Published in Canadian geotechnical journal (01-08-2012)
    “…The underlying mechanism of static and cyclic liquefaction of loose contractant sandy soil is unstable behaviour associated with deviatoric strain-softening…”
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  6. 6

    Modified state parameter for characterizing static liquefaction of sand with fines by Bobei, D. C, Lo, S. R, Wanatowski, D, Gnanendran, C. T, Rahman, M. M

    Published in Canadian geotechnical journal (01-03-2009)
    “…An experimental study was carried out to investigate the static liquefaction behaviour of sand with a small amount of plastic and nonplastic fines. Five series…”
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  7. 7

    Prediction of Undrained Monotonic and Cyclic Liquefaction Behavior of Sand with Fines Based on the Equivalent Granular State Parameter by Rahman, M. M, Baki, M. A. L, Lo, S. R

    Published in International journal of geomechanics (01-04-2014)
    “…AbstractThe undrained behavior of sand with fines under both monotonic and cyclic loading was investigated experimentally by triaxial testing. The testing…”
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  8. 8

    Equivalent granular state parameter and undrained behaviour of sand–fines mixtures by Rahman, Md. Mizanur, Lo, S. R., Baki, Md. Abdul Lahil

    Published in Acta geotechnica (01-12-2011)
    “…State parameter defined using void ratio, e , and the steady-state line has been shown to be effective in predicting the undrained behaviour of sand. However,…”
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  9. 9

    Behaviour of piles subjected to passive loading due to embankment construction by KARIM, M. R, LO, S.-C. R, GNANENDRAN, C. T

    Published in Canadian geotechnical journal (01-03-2014)
    “…Behaviour of two embedded piles subjected to passive loading due to construction of an embankment was modelled in this paper. The piles were installed at the…”
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  10. 10

    Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF by Lo, Roger S., Wotton, David, Massagué, Joan

    Published in The EMBO journal (15-01-2001)
    “…Smad transcription factors mediate the actions of transforming growth factor‐β (TGF‐β) cytokines during development and tissue homeostasis. TGF‐β…”
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  11. 11

    Long-term performance of a wide embankment on soft clay improved with prefabricated vertical drains by Lo, S. R, Mak, J, Gnanendran, C. T, Zhang, R, Manivannan, G

    Published in Canadian geotechnical journal (01-08-2008)
    “…This paper presents the long-term performance of a wide geogrid-reinforced road embankment constructed on soft clay improved with prefabricated vertical drains…”
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  12. 12
  13. 13

    The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-β receptors by Lo, Roger S., Chen, Ye-Guang, Shi, Yigong, Pavletich, Nikola P., Massagué, Joan

    Published in The EMBO journal (15-02-1998)
    “…Signal transduction specificity in the transforming growth factor‐β (TGF‐β) system is determined by ligand activation of a receptor complex which then recruits…”
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  14. 14

    Laboratory assessment of electro-osmotic stabilization of soft clay by JEYAKANTHAN, V, GNANENDRAN, C. T, LO, S.-C. R

    Published in Canadian geotechnical journal (01-12-2011)
    “…The application of electro-osmosis (EO) for stabilizing soft clays is receiving more attention in geotechnical engineering. When the application of traditional…”
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  15. 15
  16. 16

    Predicting the long-term performance of a geogrid-reinforced embankment on soft soil using two-dimensional finite element analysis by KARIM, M. R, MANIVANNAN, G, GNANENDRAN, C. T, LO, S-C. R

    Published in Canadian geotechnical journal (01-05-2011)
    “…The consolidation of the soft foundation soil of a geogrid-reinforced embankment, improved with prefabricated vertical drains (PVDs), is modelled in this paper…”
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  17. 17

    Effect of Slip-Hardening Interface Behavior on Fiber Rupture and Crack Bridging in Fiber-Reinforced Cementitious Composites by Huang, Ting, Zhang, Y. X, Su, Cheng, Lo, S. R

    Published in Journal of engineering mechanics (01-10-2015)
    “…AbstractA generic crack bridging model for short fiber-reinforced cementitious composites is developed aiming to analytically account for fiber tensile rupture…”
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  18. 18

    The effect of drained pre-shearing on the undrained behaviour of loose sand with a small amount of fines by Bobei, D. C., Wanatowski, D., Rahman, M. M., Lo, S. R., Gnanendran, C. T.

    Published in Acta geotechnica (01-06-2013)
    “…Stress history is recognised to play a major role in determining stress–strain behaviour of soil in undrained shearing. Most experimental studies on the…”
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  19. 19

    Strength and dilatancy of a silt stabilized by a cement and fly ash mixture by Lo, S R, Wardani, S PR

    Published in Canadian geotechnical journal (01-02-2002)
    “…The mechanical behaviour of a weakly cemented silt was studied experimentally. The cementing agent was a cement and fly ash slurry, and the samples so formed…”
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  20. 20

    Strain-softening behaviour of sand in strain path testing under plane-strain conditions by Wanatowski, D., Chu, J., Lo, R. S.-C.

    Published in Acta geotechnica (01-06-2008)
    “…Experimental data are presented in this paper to study the strain-softening behaviour of sand under plane-strain conditions. K 0 consolidated strain path tests…”
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