Search Results - "Lo, S. R."
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Rho-mediated signaling promotes BRAF inhibitor resistance in de-differentiated melanoma cells
Published in Oncogene (13-02-2020)“…Over half of cutaneous melanoma tumors have BRAF V600E/K mutations. Acquired resistance to BRAF inhibitors (BRAFi) remains a major hurdle in attaining durable…”
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Undrained Behavior of Sand-Fines Mixtures and Their State Parameter
Published in Journal of geotechnical and geoenvironmental engineering (01-07-2014)“…AbstractThe influence of fines on the undrained behavior of sand was investigated experimentally over a range of fines content and effective mean stress. The…”
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On equivalent granular void ratio and steady state behaviour of loose sand with fines
Published in Canadian geotechnical journal (01-10-2008)“…Void ratio has traditionally been used as a state variable for predicting the liquefaction behaviour of soils under the critical state soil mechanics…”
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Predicting the Onset of Static Liquefaction of Loose Sand with Fines
Published in Journal of geotechnical and geoenvironmental engineering (01-08-2012)“…AbstractLoose sandy soil subject to undrained shearing manifests deviatoric strain softening, and such a behavior has been referred to as collapse, static…”
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Linkage between static and cyclic liquefaction of loose sand with a range of fines contents
Published in Canadian geotechnical journal (01-08-2012)“…The underlying mechanism of static and cyclic liquefaction of loose contractant sandy soil is unstable behaviour associated with deviatoric strain-softening…”
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Modified state parameter for characterizing static liquefaction of sand with fines
Published in Canadian geotechnical journal (01-03-2009)“…An experimental study was carried out to investigate the static liquefaction behaviour of sand with a small amount of plastic and nonplastic fines. Five series…”
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Prediction of Undrained Monotonic and Cyclic Liquefaction Behavior of Sand with Fines Based on the Equivalent Granular State Parameter
Published in International journal of geomechanics (01-04-2014)“…AbstractThe undrained behavior of sand with fines under both monotonic and cyclic loading was investigated experimentally by triaxial testing. The testing…”
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Equivalent granular state parameter and undrained behaviour of sand–fines mixtures
Published in Acta geotechnica (01-12-2011)“…State parameter defined using void ratio, e , and the steady-state line has been shown to be effective in predicting the undrained behaviour of sand. However,…”
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Behaviour of piles subjected to passive loading due to embankment construction
Published in Canadian geotechnical journal (01-03-2014)“…Behaviour of two embedded piles subjected to passive loading due to construction of an embankment was modelled in this paper. The piles were installed at the…”
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Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF
Published in The EMBO journal (15-01-2001)“…Smad transcription factors mediate the actions of transforming growth factor‐β (TGF‐β) cytokines during development and tissue homeostasis. TGF‐β…”
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Long-term performance of a wide embankment on soft clay improved with prefabricated vertical drains
Published in Canadian geotechnical journal (01-08-2008)“…This paper presents the long-term performance of a wide geogrid-reinforced road embankment constructed on soft clay improved with prefabricated vertical drains…”
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The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-β receptors
Published in The EMBO journal (15-02-1998)“…Signal transduction specificity in the transforming growth factor‐β (TGF‐β) system is determined by ligand activation of a receptor complex which then recruits…”
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Laboratory assessment of electro-osmotic stabilization of soft clay
Published in Canadian geotechnical journal (01-12-2011)“…The application of electro-osmosis (EO) for stabilizing soft clays is receiving more attention in geotechnical engineering. When the application of traditional…”
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Meeting report from the Society for Melanoma Research 2012 Congress, Hollywood, California
Published in Pigment Cell & Melanoma Research (01-07-2013)Get full text
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Predicting the long-term performance of a geogrid-reinforced embankment on soft soil using two-dimensional finite element analysis
Published in Canadian geotechnical journal (01-05-2011)“…The consolidation of the soft foundation soil of a geogrid-reinforced embankment, improved with prefabricated vertical drains (PVDs), is modelled in this paper…”
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Effect of Slip-Hardening Interface Behavior on Fiber Rupture and Crack Bridging in Fiber-Reinforced Cementitious Composites
Published in Journal of engineering mechanics (01-10-2015)“…AbstractA generic crack bridging model for short fiber-reinforced cementitious composites is developed aiming to analytically account for fiber tensile rupture…”
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The effect of drained pre-shearing on the undrained behaviour of loose sand with a small amount of fines
Published in Acta geotechnica (01-06-2013)“…Stress history is recognised to play a major role in determining stress–strain behaviour of soil in undrained shearing. Most experimental studies on the…”
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Strength and dilatancy of a silt stabilized by a cement and fly ash mixture
Published in Canadian geotechnical journal (01-02-2002)“…The mechanical behaviour of a weakly cemented silt was studied experimentally. The cementing agent was a cement and fly ash slurry, and the samples so formed…”
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Strain-softening behaviour of sand in strain path testing under plane-strain conditions
Published in Acta geotechnica (01-06-2008)“…Experimental data are presented in this paper to study the strain-softening behaviour of sand under plane-strain conditions. K 0 consolidated strain path tests…”
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