Search Results - "Lo, Amy Cheuk Yin"

Novel Programmed Cell Death as Therapeutic Targets in Age-Related Macular Degeneration? by Yang, Ming, So, Kwok-Fai, Lam, Wai Ching, Lo, Amy Cheuk Yin

“…Age-related macular degeneration (AMD) is a leading cause of severe visual loss among the elderly. AMD patients are tormented by progressive central…”
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The Effect of Lycium barbarum Polysaccharides on Pyroptosis-Associated Amyloid β1-40 Oligomers-Induced Adult Retinal Pigment Epithelium 19 Cell Damage by Yang, Ming, So, Kwok-Fai, Lo, Amy Cheuk Yin, Lam, Wai Ching

“…Age-related macular degeneration (AMD) is a sight-threatening disease with limited treatment options. We investigated whether amyloid β1-40 (Aβ1-40) could…”
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Physical exercise and glaucoma: a review on the roles of physical exercise on intraocular pressure control, ocular blood flow regulation, neuroprotection and glaucoma‐related mental health by Zhu, Ming Ming, Lai, Jimmy Shiu Ming, Choy, Bonnie Nga Kwan, Shum, Jennifer Wei Huen, Lo, Amy Cheuk Yin, Ng, Alex Lap Ki, Chan, Jonathan Cheuk Hung, So, Kwok Fai

“…The benefits of physical exercise on health and well‐being have been studied in a wide range of systemic and ocular diseases, including glaucoma, a progressive…”
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Nutraceuticals for Diabetic Retinopathy: Recent Advances and Novel Delivery Systems by Ye, Xiaoyuan, Fung, Nicholas Siu Kay, Lam, Wai Ching, Lo, Amy Cheuk Yin

“…Diabetic retinopathy (DR) is a major vision-threatening disease among the working-age population worldwide. Present therapeutic strategies such as intravitreal…”
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Green Light‐Triggered Intraocular Drug Release for Intravenous Chemotherapy of Retinoblastoma by Long, Kaiqi, Yang, Yang, Lv, Wen, Jiang, Kuan, Li, Yafei, Lo, Amy Cheuk Yin, Lam, Wai Ching, Zhan, Changyou, Wang, Weiping

“…Retinoblastoma is one of the most severe ocular diseases, of which current chemotherapy is limited to the repetitive intravitreal injections of…”
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Bioactive Glial-Derived Neurotrophic Factor from a Safe Injectable Collagen-Alginate Composite Gel Rescues Retinal Photoreceptors from Retinal Degeneration in Rabbits by Hu, Tingyu, Zhou, Ting, Goit, Rajesh Kumar, Tam, Ka Cheung, Chan, Yau Kei, Lam, Wai-Ching, Lo, Amy Cheuk Yin

“…The management of vision-threatening retinal diseases remains challenging due to the lack of an effective drug delivery system. Encapsulated cell therapy (ECT)…”
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Protection of retinal ganglion cells and retinal vasculature by Lycium barbarum polysaccharides in a mouse model of acute ocular hypertension by Mi, Xue-Song, Feng, Qian, Lo, Amy Cheuk Yin, Chang, Raymond Chuen-Chung, Lin, Bin, Chung, Sookja Kim, So, Kwok-Fai

“…Acute ocular hypertension (AOH) is a condition found in acute glaucoma. The purpose of this study is to investigate the protective effect of Lycium barbarum…”
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Autophagic Upregulation Is Cytoprotective in Ischemia/Reperfusion-Injured Retina and Retinal Progenitor Cells by Tang, Larissa Ho Ching, Fung, Frederic Khe Cheong, Lai, Angela Ka Wai, Wong, Ian Yat Hin, Shih, Kendrick Co, Lo, Amy Cheuk Yin

“…The cytoprotective versus cytotoxic role of macroautophagy in ocular ischemia/reperfusion injuries remains controversial and its effects under hyperglycemia…”
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The association between altered intestinal microbiome, impaired systemic and ocular surface immunity, and impaired wound healing response after corneal alkaline-chemical injury in diabetic mice by Bu, Yashan, Shih, Kendrick Co, Wong, Ho Lam, Kwok, Sum Sum, Lo, Amy Cheuk-Yin, Chan, Joseph Yau-Kei, Ng, Alex Lap-Ki, Chan, Tommy Chung-Yan, Jhanji, Vishal, Tong, Louis

“…We aim to investigate the effect of sustained hyperglycemia on corneal epithelial wound healing, ocular surface and systemic immune response, and microbiome…”
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mTOR Signalling Pathway: A Potential Therapeutic Target for Ocular Neurodegenerative Diseases by Wang, Yipin, Fung, Nicholas Siu Kay, Lam, Wai-Ching, Lo, Amy Cheuk Yin

“…Recent advances in the research of the mammalian target of the rapamycin (mTOR) signalling pathway demonstrated that mTOR is a robust therapeutic target for…”
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Ferroptosis and glaucoma: implications in retinal ganglion cell damage and optic nerve survival by Yang, Ming, So, Kwok-Fai, Lam, Wai-Ching, Yin Lo, Amy

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Cell Ferroptosis: New Mechanism and New Hope for Retinitis Pigmentosa by Yang, Ming, So, Kwok-Fai, Lam, Wai-Ching, Lo, Amy Cheuk Yin

“…Retinitis pigmentosa (RP) is a leading cause of inherited retinal degeneration, with more than 60 gene mutations. Despite the genetic heterogenicity,…”
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Comparison of electroretinographic responses between two different age groups of adult Dark Agouti rats by Fu, Lin, Lo, Amy Cheuk Yin, Lai, Jimmy Shiu Ming, Shih, Kendrick Co

“…AIM: To describe and compare the differences in electroretinographic responses between two different age groups of adult Dark Agouti(DA) rats and to better…”
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The role of electrical stimulation therapy in ophthalmic diseases by Fu, Lin, Lo, Amy Cheuk Yin, Lai, Jimmy Shiu Ming, Shih, Kendrick Co

“…Introduction Electrical stimulation therapy (EST) involves the use of a low-intensity electrical current in the treatment of neuromuscular conditions. During…”
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Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury by Fu, Lin, Fung, Frederic K, Lo, Amy Cheuk-Yin, Chan, Yau-Kei, So, Kwok-Fai, Wong, Ian Yat-Hin, Shih, Kendrick Co, Lai, Jimmy Shiu-Ming

“…To investigate the effect of transcorneal electrical stimulation (TcES) on retinal ganglion cell (RGC) function and survival after acute ocular…”
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Long-term lutein administration attenuates retinal inflammation and functional deficits in early diabetic retinopathy using the Ins2Akita/+ mice by Wang, Wei, Tam, Ka Cheung, Ng, Tsz Chung, Goit, Rajesh Kumar, Chan, Kate Lok San, Lo, Amy Cheuk Yin

“…IntroductionLutein is a carotenoid whose protective effects in the retina have been reported in various studies. The effect of lutein has not been reported in…”
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Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs by Chan, Jasper Fuk-Woo, Yip, Cyril Chik-Yan, Tsang, Jessica Oi-Ling, Tee, Kah-Meng, Cai, Jian-Piao, Chik, Kenn Ka-Heng, Zhu, Zheng, Chan, Chris Chung-Sing, Choi, Garnet Kwan-Yue, Sridhar, Siddharth, Zhang, Anna Jinxia, Lu, Gang, Chiu, Kin, Lo, Amy Cheuk-Yin, Tsao, Sai-Wah, Kok, Kin-Hang, Jin, Dong-Yan, Chan, Kwok-Hung, Yuen, Kwok-Yung

“…Zika virus (ZIKV) is unique among human-pathogenic flaviviruses by its association with congenital anomalies and trans-placental and sexual human-to-human…”
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Lutein Supplementation for Eye Diseases by Li, Long Hin, Lee, Jetty Chung-Yung, Leung, Ho Hang, Lam, Wai Ching, Fu, Zhongjie, Lo, Amy Cheuk Yin

“…Lutein is one of the few xanthophyll carotenoids that is found in high concentration in the macula of human retina. As synthesis of lutein within the human…”
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Diabetic Corneal Neuropathy: Pathogenic Mechanisms and Therapeutic Strategies by Zhou, Ting, Lee, Allie, Lo, Amy Cheuk Yin, Kwok, Jeremy Sze Wai John

“…Diabetes mellitus (DM) is a major global public health problem that can cause complications such as diabetic retinopathy, diabetic neuropathy, and diabetic…”
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Involvement of FSP1-CoQ10-NADH and GSH-GPx-4 pathways in retinal pigment epithelium ferroptosis by Yang, Ming, Tsui, Michelle Grace, Tsang, Jessica Kwan Wun, Goit, Rajesh Kumar, Yao, Kwok-Ming, So, Kwok-Fai, Lam, Wai-Ching, Lo, Amy Cheuk Yin

“…Retinal pigment epithelium (RPE) degeneration plays an important role in a group of retinal disorders such as retinal degeneration (RD) and age-related macular…”
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