Search Results - "Lo, Allen T. Y."

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  1. 1

    Structural characterisation of the complete cycle of sliding clamp loading in Escherichia coli by Xu, Zhi-Qiang, Jergic, Slobodan, Lo, Allen T. Y., Pradhan, Alok C., Brown, Simon H. J., Bouwer, James C., Ghodke, Harshad, Lewis, Peter J., Tolun, Gökhan, Oakley, Aaron J., Dixon, Nicholas E.

    Published in Nature communications (27-09-2024)
    “…Ring-shaped DNA sliding clamps are essential for DNA replication and genome maintenance. Clamps need to be opened and chaperoned onto DNA by clamp loader…”
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  2. 2

    Escherichia coli Single-Stranded DNA-Binding Protein: NanoESI-MS Studies of Salt-Modulated Subunit Exchange and DNA Binding Transactions by Mason, Claire E., Jergic, Slobodan, Lo, Allen T. Y., Wang, Yao, Dixon, Nicholas E., Beck, Jennifer L.

    “…Single-stranded DNA-binding proteins (SSBs) are ubiquitous oligomeric proteins that bind with very high affinity to single-stranded DNA and have a variety of…”
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  3. 3

    Fragment-Based Discovery of Inhibitors of the Bacterial DnaG-SSB Interaction by Chilingaryan, Zorik, Headey, Stephen J, Lo, Allen T Y, Xu, Zhi-Qiang, Otting, Gottfried, Dixon, Nicholas E, Scanlon, Martin J, Oakley, Aaron J

    Published in Antibiotics (Basel) (22-02-2018)
    “…In bacteria, the DnaG primase is responsible for synthesis of short RNA primers used to initiate chain extension by replicative DNA polymerase(s) during…”
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  4. 4

    A Primase-Induced Conformational Switch Controls the Stability of the Bacterial Replisome by Monachino, Enrico, Jergic, Slobodan, Lewis, Jacob S., Xu, Zhi-Qiang, Lo, Allen T.Y., O’Shea, Valerie L., Berger, James M., Dixon, Nicholas E., van Oijen, Antoine M.

    Published in Molecular cell (02-07-2020)
    “…Recent studies of bacterial DNA replication have led to a picture of the replisome as an entity that freely exchanges DNA polymerases and displays intermittent…”
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    Journal Article