Search Results - "Lo, Alexandra"
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Oligodeoxynucleotide inhibition of Toll‐like receptors 3, 7, 8, and 9 suppresses cytokine production in a human rheumatoid arthritis model
Published in European journal of immunology (01-03-2016)“…Toll‐like receptors (TLRs) are innate immune receptors that respond to both exogenous and endogenous stimuli and are suggested to contribute to the…”
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Inhibitors of TLR8 Reduce TNF Production from Human Rheumatoid Synovial Membrane Cultures
Published in The Journal of immunology (1950) (01-12-2008)“…The advent of anti-TNF biologicals has been a seminal advance in the treatment of rheumatoid arthritis (RA) and has confirmed the important role of TNF in…”
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A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia
Published in Nature genetics (01-04-2008)“…We report the first identified mutation in the gene encoding human cytochrome c (CYCS). Glycine 41, invariant throughout eukaryotes, is substituted by serine…”
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How much do Hong Kong emergency physicians know about common legal situations?
Published in Journal of forensic and legal medicine (01-02-2010)Get full text
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5
Evolution in the diagnosis and treatment of carcinoma of unknown primary: a multicenter Canadian analysis
Published in The oncologist (Dayton, Ohio) (09-11-2024)“…Guidelines for the management of patients with cancer of unknown primary (CUP), who have metastatic disease without an identified primary tumor site, have…”
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A randomized controlled study of acupuncture for pain relief during first trimester surgical termination of pregnancy performed under local analgesia
Published in Acupuncture in medicine : journal of the British Medical Acupuncture Society (01-06-2022)“…Background: Acupuncture reduces pain levels in many painful conditions. This study compared pain levels during surgical termination of first trimester…”
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Conformational change and human cytochrome c function: mutation of residue 41 modulates caspase activation and destabilizes Met-80 coordination
Published in Journal of biological inorganic chemistry (01-03-2013)“…Cytochrome c is a highly conserved protein, with 20 residues identical in all eukaryotic cytochromes c . Gly-41 is one of these invariant residues, and is…”
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A proapoptotic mutation in human cytochrome c associated with abnormal platelet production
Published in The FASEB journal (01-03-2006)“…Cytochrome c is a highly conserved protein with dual roles in mitochondrial electron transport and apoptosis. We have identified the first known mutation in…”
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132 Toll-like Receptors (TLRS) Contribute in the Inflammation and Pathogenesis of RA
Published in Cytokine (Philadelphia, Pa.) (01-07-2007)Get full text
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