Search Results - "Lo, Alexandra"

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    Oligodeoxynucleotide inhibition of Toll‐like receptors 3, 7, 8, and 9 suppresses cytokine production in a human rheumatoid arthritis model by Sacre, Sandra, Lo, Alexandra, Gregory, Bernard, Stephens, Matthew, Chamberlain, Giselle, Stott, Philip, Brennan, Fionula

    Published in European journal of immunology (01-03-2016)
    “…Toll‐like receptors (TLRs) are innate immune receptors that respond to both exogenous and endogenous stimuli and are suggested to contribute to the…”
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    Journal Article
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    Inhibitors of TLR8 Reduce TNF Production from Human Rheumatoid Synovial Membrane Cultures by Sacre, Sandra M, Lo, Alexandra, Gregory, Bernard, Simmonds, Rachel E, Williams, Lynn, Feldmann, Marc, Brennan, Fionula M, Foxwell, Brian M

    Published in The Journal of immunology (1950) (01-12-2008)
    “…The advent of anti-TNF biologicals has been a seminal advance in the treatment of rheumatoid arthritis (RA) and has confirmed the important role of TNF in…”
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    Evolution in the diagnosis and treatment of carcinoma of unknown primary: a multicenter Canadian analysis by Wong, Boaz, Liu, Jessica, Yeo, Sarah, Akurang, Deborah, Lo, Alexandra, Xu, Ying Hui, Wang, Ying, Welch, Stephen, Wheatley-Price, Paul

    Published in The oncologist (Dayton, Ohio) (09-11-2024)
    “…Guidelines for the management of patients with cancer of unknown primary (CUP), who have metastatic disease without an identified primary tumor site, have…”
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    Conformational change and human cytochrome c function: mutation of residue 41 modulates caspase activation and destabilizes Met-80 coordination by Josephs, Tracy M., Liptak, Matthew D., Hughes, Gillian, Lo, Alexandra, Smith, Rebecca M., Wilbanks, Sigurd M., Bren, Kara L., Ledgerwood, Elizabeth C.

    Published in Journal of biological inorganic chemistry (01-03-2013)
    “…Cytochrome  c is a highly conserved protein, with 20 residues identical in all eukaryotic cytochromes  c . Gly-41 is one of these invariant residues, and is…”
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    A proapoptotic mutation in human cytochrome c associated with abnormal platelet production by Ledgerwood, Elizabeth, Cheong, Anthony, Lo, Alexandra, Cramer, Elisabeth, Morison, Ian

    Published in The FASEB journal (01-03-2006)
    “…Cytochrome c is a highly conserved protein with dual roles in mitochondrial electron transport and apoptosis. We have identified the first known mutation in…”
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