Search Results - "Llwyd, Osian"

Effect of drug interventions on cerebral hemodynamics in ischemic stroke patients by Llwyd, Osian, Fan, Jui-Lin, Müller, Martin

“…The ischemic penumbra is sensitive to alterations in cerebral perfusion. A myriad of drugs are used in acute ischemic stroke (AIS) management, yet their impact…”
Get full text

Cerebral autoregulation and response to intravenous thrombolysis for acute ischemic stroke by Nogueira, Ricardo C., Lam, Man Y., Llwyd, Osian, Salinet, Angela S. M., Bor-Seng-Shu, Edson, Panerai, Ronney B., Robinson, Thompson G.

“…We hypothesized that knowledge of cerebral autoregulation (CA) status during recanalization therapies could guide further studies aimed at neuroprotection…”
Get full text

Cerebral critical closing pressure and resistance-area product: the influence of dynamic cerebral autoregulation, age and sex by Panerai, Ronney B, Haunton, Victoria J, Llwyd, Osian, Minhas, Jatinder S, Katsogridakis, Emmanuel, Salinet, Angela SM, Maggio, Paola, Robinson, Thompson G

“…Instantaneous arterial pressure-flow (or velocity) relationships indicate the existence of a cerebral critical closing pressure (CrCP), with the slope of the…”
Get full text

The critical closing pressure contribution to dynamic cerebral autoregulation in humans: influence of arterial partial pressure of CO2 by Panerai, Ronney B., Minhas, Jatinder S., Llwyd, Osian, Salinet, Angela S. M., Katsogridakis, Emmanuel, Maggio, Paola, Robinson, Thompson G

“…Key points Dynamic cerebral autoregulation (CA) is often expressed by the mean arterial blood pressure (MAP)–cerebral blood flow (CBF) relationship, with…”
Get full text

Can we use short recordings for assessment of dynamic cerebral autoregulation? A sensitivity analysis study in acute ischaemic stroke and healthy subjects by Intharakham, Kannakorn, Panerai, Ronney B, Katsogridakis, Emmanuel, Lam, Man Y, Llwyd, Osian, Salinet, Angela S M, Nogueira, Ricardo C, Haunton, Victoria, Robinson, Thompson G

“…It is unclear whether the duration of recordings influences estimates of dynamic cerebral autoregulation (dCA). Therefore, we performed a retrospective study…”
Get more information

Chasing the evidence: the influence of data segmentation on estimates of dynamic cerebral autoregulation by Panerai, Ronney B, Intharakham, Kannakorn, Haunton, Victoria, Minhas, Jatinder S, Llwyd, Osian, Lam, Manda, Salinet, Angela S M, Nogueira, Ricardo C, Katsogridakis, Emmanuel, Maggio, Paola, Robinson, Thompson G

“…Transfer function analysis (TFA) of dynamic cerebral autoregulation (dCA) requires smoothing of spectral estimates using segmentation of the data (S )…”
Get more information

A Multi-Parametric Approach for Characterising Cerebral Haemodynamics in Acute Ischaemic and Haemorrhagic Stroke by Alshehri, Abdulaziz, Panerai, Ronney B, Salinet, Angela, Lam, Man Yee, Llwyd, Osian, Robinson, Thompson G, Minhas, Jatinder S

“…Early differentiation between acute ischaemic (AIS) and haemorrhagic stroke (ICH), based on cerebral and peripheral hemodynamic parameters, would be…”
Get full text

Extremes of cerebral blood flow during hypercapnic squat‐stand maneuvers by Barnes, Samuel C., Haunton, Victoria J., Beishon, Lucy, Llwyd, Osian, Robinson, Thompson G., Panerai, Ronney B.

“…Squat‐stand maneuvers (SSMs) are a popular method of inducing blood pressure (BP) oscillations to reliably assess dynamic cerebral autoregulation (dCA), but…”
Get full text

Cerebral Haemodynamics following Acute Ischaemic Stroke: Effects of Stroke Severity and Stroke Subtype by Llwyd, Osian, Salinet, Angela S.M., Panerai, Ronney B., Lam, Man Y., Saeed, Nazia P., Brodie, Fiona, Bor-Seng-Shu, Edson, Robinson, Thompson G., Nogueira, Ricardo C.

“…Background: Acute ischaemic stroke (AIS) patients often show impaired cerebral autoregulation (CA). We tested the hypothesis that CA impairment and other…”
Get full text

Cerebrovascular Effects of Sildenafil in Small Vessel Disease: The OxHARP Trial by Webb, Alastair J S, Birks, Jacqueline, Feakins, Karolina A, Lawson, Amy, Dawson, Jesse, Rothman, Alexander M K, Werring, David J, Llwyd, Osian, Stewart, Catriona, Thomas, James

“…Vascular cognitive impairment due to cerebral small vessel disease is associated with cerebral pulsatility, white matter hypoperfusion, and reduced…”
Get full text

Effects of dominant and non-dominant passive arm manoeuvres on the neurovascular coupling response by Llwyd, Osian, Panerai, Ronney B., Robinson, Thompson G.

“…Purpose Models designed to study neurovascular coupling (NVC) describe a possible cerebral hemisphere dominance dependent on task completed and preference in…”
Get full text

Determinants of the dynamic cerebral critical closing pressure response to changes in mean arterial pressure by Panerai, Ronney B, Alshehri, Abdulaziz, Beishon, Lucy C, Davies, Aaron, Haunton, Victoria J, Katsogridakis, Emmanuel, Lam, Man Y, Llwyd, Osian, Robinson, Thompson G, Minhas, Jatinder S

“… Cerebral critical closing pressure (CrCP) represents the value of arterial blood pressure (BP) where cerebral blood flow (CBF) becomes zero. Its dynamic…”
Get more information

The critical closing pressure contribution to dynamic cerebral autoregulation in humans: influence of arterial partial pressure of CO 2 by Panerai, Ronney B, Minhas, Jatinder S, Llwyd, Osian, Salinet, Angela S M, Katsogridakis, Emmanuel, Maggio, Paola, Robinson, Thompson G

“…Dynamic cerebral autoregulation (CA) is often expressed by the mean arterial blood pressure (MAP)-cerebral blood flow (CBF) relationship, with little attention…”
Get full text

Differences in the profile of protection afforded by TRO40303 and mild hypothermia in models of cardiac ischemia/reperfusion injury by Hansson, Magnus J., Llwyd, Osian, Morin, Didier, de Paulis, Damien, Arnoux, Thomas, Gouarné, Caroline, Koul, Sasha, Engblom, Henrik, Bordet, Thierry, Tissier, Renaud, Arheden, Haakan, Erlinge, David, Halestrap, Andrew P., Berdeaux, Alain, Pruss, Rebecca M., Schaller, Sophie

“…The mode of protection against cardiac reperfusion injury by mild hypothermia and TRO40303 was investigated in various experimental models and compared to…”
Get full text

Can we assess dynamic cerebral autoregulation in stroke patients with high rates of cardiac ectopicity? by Llwyd, Osian, Haunton, Victoria, Salinet, Angela S.M., Nath, Mintu, Lam, Man Y., Saeed, Nazia P., Brodie, Fiona, Robinson, Thompson G., Panerai, Ronney B.

“…It is unclear whether physiological recordings containing high numbers of ectopic heartbeats can be used to measure the cerebral autoregulation (CA) of blood…”
Get full text

The involvement of camkii in myocardial ischaemia-reperfusion injury by Llwyd, Osian

“…CaMKII acts as a second messenger to Ca2+ signals within the cardiac myocyte. Cellular stresses such as ischaemia and subsequent reperfusion perturb the normal…”
Get full text

Extremes of cerebral blood flow during hypercapnic squat-stand maneuvers by Barnes, Samuel C, Haunton, Victoria J, Beishon, Lucy, Llwyd, Osian, Robinson, Thompson G, Panerai, Ronney B

“…Squat-stand maneuvers (SSMs) are a popular method of inducing blood pressure (BP) oscillations to reliably assess dynamic cerebral autoregulation (dCA), but…”
Get full text