Search Results - "Lluka, Lesley J"

Effects of long-term opioid analgesics on cognitive performance and plasma cytokine concentrations in patients with chronic low back pain: a cross-sectional pilot study by Richards, Georgia C., Lluka, Lesley J., Smith, Maree T., Haslam, Catherine, Moore, Brendan, O'Callaghan, James, Strong, Jenny

“…Cognitive performance and inflammation are altered in people with chronic low back pain (CLBP). Yet, the magnitude of these changes has been unclear because of…”
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A Role for Serotonin (5-HT) in Hepatic Stellate Cell Function and Liver Fibrosis by Ruddell, Richard G., Oakley, Fiona, Hussain, Ziafat, Yeung, Irene, Bryan-Lluka, Lesley J., Ramm, Grant A., Mann, Derek A.

“…Hepatic stellate cells (HSCs) are key cellular components of hepatic wound healing and fibrosis. There is emerging evidence that the fibrogenic function of…”
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Roles of transmembrane domain 2 and the first intracellular loop in human noradrenaline transporter function: pharmacological and SCAM analysis by Sucic, Sonja, Bryan‐Lluka, Lesley J.

“…The aim was to investigate the roles of transmembrane domain 2 and the adjacent region of the first intracellular loop in determining human noradrenaline…”
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Nitric oxide donors inhibit 5‐hydroxytryptamine (5‐HT) uptake by the human 5‐HT transporter (SERT) by Bryan‐Lluka, Lesley J, Papacostas, Marisa H, Paczkowski, Filip A, Wanstall, Janet C

“…The aim was to test the hypothesis that nitric oxide (NO) donor drugs can inhibit the 5‐hydroxytryptamine (5‐HT) transporter, SERT. The NO donors, MAHMA/NO (a…”
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SOLO-Based Task to Improve Self-Evaluation and Capacity to Integrate Concepts in First-Year Physiology Students by Williams, Mark T, Lluka, Lesley J, Meyer, Jan H. F, Chunduri, Prasad

“…An accurate self-assessment of student work can enhance student learning and subsequently improve academic performance. Instructors can facilitate this process…”
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Extracellular loop 3 of the noradrenaline transporter contributes to substrate and inhibitor selectivity by Lynagh, Timothy, Khamu, Tina S., Bryan-Lluka, Lesley J.

“…The human noradrenaline transporter (NET) and 5-hydroxytryptamine (5-HT) transporter (SERT) are inhibited by antidepressants and psychoactive drugs such as…”
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A Set of Vertically Integrated Inquiry-Based Practical Curricula that Develop Scientific Thinking Skills for Large Cohorts of Undergraduate Students by Zimbardi, Kirsten, Bugarcic, Andrea, Colthorpe, Kay, Good, Jonathan P, Lluka, Lesley J

“…Science graduates require critical thinking skills to deal with the complex problems they will face in their 21st century workplaces. Inquiry-based curricula…”
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Functional significance of a highly conserved glutamate residue of the human noradrenaline transporter by Sucic, Sonja, Paczkowski, Filip A., Runkel, Fabian, Bönisch, Heinz, Bryan‐Lluka, Lesley J.

“…The aim of the study was to investigate the role of glutamate residue 113 in transmembrane domain 2 of the human noradrenaline transporter in determining cell…”
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Investigation of the functional roles of the MELAL and GQXXRXG motifs of the human noradrenaline transporter using cysteine mutants by Sucic, Sonja, Bryan-Lluka, Lesley J.

“…The study examines the roles of the highly conserved MELAL and GQXXRXG motifs, located in the second transmembrane domain and the first intracellular loop of…”
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Dose determination of haloperidol, risperidone and olanzapine using an in vivo dopamine D2-receptor occupancy method in the rat by NAIKER, Dineshree V, CARTS, Stanley V, CATTS, Vibeke S, BEDI, Kuldip S, BRYAN-LLUKA, Lesley J

“…The purpose of the present study was to determine antipsychotic doses that achieve 80% striatal dopamine D2-receptor occupancy for haloperidol, risperidone and…”
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χ-Conopeptide MrIA Partially Overlaps Desipramine and Cocaine Binding Sites on the Human Norepinephrine Transporter by Bryan-Lluka, Lesley J., Bönisch, Heinz, Lewis, Richard J.

“…The interactions of χ-conopeptide MrIA with the human norepinephrine transporter (hNET) were investigated by determining the effects of hNET point mutations on…”
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Assessing core manipulative skills in a large, first-year laboratory by Moni, Roger W, Hryciw, Deanne H, Poronnik, Philip, Lluka, Lesley J, Moni, Karen B

“…1 Educational Research Unit The University of Queensland, Brisbane, Queensland, Australia 2 Education, School of Biomedical Sciences, The University of…”
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Quantitative analysis of immunolabeling for serotonin and for glutamate transporters after administration of imipramine and citalopram by Williams, Susan M., Bryan-Lluka, Lesley J., Pow, David V.

“…Serotonin (5-hydroxytryptamine, 5-HT) is an amine neurotransmitter derived from tryptophan and is important in brain systems regulating mood, emotional…”
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The personal response: A novel writing assignment to engage first year students in large human biology classes by Moni, Roger W., Moni, Karen B., Lluka, Lesley J., Poronnik, Philip

“…The teaching of highly valued scientific writing skills in the first year of university is challenging. This report describes the design, implementation, and…”
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Biohorizons: An eConference to Assess Human Biology in Large, First-Year Classes by Moni, Roger W, Moni, Karen B, Poronnik, Philip, Lluka, Lesley J

“…The authors detail the design, implementation and evaluation of an eConference entitled "Biohorizons," using a presage-process-product model to describe the…”
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Effects of short- and long-term exposure to c-AMP and c-GMP on the noradrenaline transporter by Bryan-Lluka, Lesley J., Paczkowski, Filip A., Bönisch, Heinz

“…The effects of short- and long-term exposure of cells to elevated cyclic adenosine monophosphate (c-AMP), using dibutyryl-c-AMP, 8-bromo-c-AMP, cholera toxin…”
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Amino acids involved in differences in the pharmacological profiles of the rat and human noradrenaline transporters by Paczkowski, Filip A, Bryan-Lluka, Lesley J

“…It has been suggested from a previous study in our laboratory that differences in the pharmacology of the species variants of the noradrenaline transporter…”
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Comparison of the pharmacological properties of cloned rat, human, and bovine norepinephrine transporters by Paczkowski, F A, Bryan-Lluka, L J, Pörzgen, P, Brüss, M, Bönisch, H

“…The aims of this study were to characterize the recently cloned rat norepinephrine transporter (NET) in more detail and in particular to study possible species…”
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Specific uptake of 5-hydroxytryptamine is reduced in lungs from hypoxic pulmonary hypertensive rats by Jeffery, Trina K, Bryan-Lluka, Lesley J, Wanstall, Janet C

“…In this study, the aim was to determine whether 5-hydroxytryptamine (5-HT) removal by the pulmonary endothelium is reduced in 1-week hypoxic, pulmonary…”
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5-Hydroxytryptamine and platelets: uptake and aggregation in hypoxic pulmonary hypertensive rats by Awabdy, Doreen, Bryan-Lluka, Lesley J., Wanstall, Janet C.

“…Pulmonary hypertension is associated with various alterations in 5-hydroxytryptamine (5-HT) physiology. In this study in platelets from hypoxic pulmonary…”
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