Search Results - "Lloyd, Paul"
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Diabetic retinopathy and other ocular findings in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study
Published in Diabetes care (01-01-2014)“…OBJECTIVE To evaluate whether intensive treatment (INT) with the goal of achieving blood glucose levels as close to the nondiabetic range as safely possible…”
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Peripheral Lesions Identified on Ultrawide Field Imaging Predict Increased Risk of Diabetic Retinopathy Progression over 4 Years
Published in Ophthalmology (Rochester, Minn.) (01-05-2015)“…Objective To determine whether peripheral diabetic retinopathy (DR) lesions identified on ultrawide field (UWF) imaging are associated with increased DR…”
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Peripheral Lesions Identified by Mydriatic Ultrawide Field Imaging: Distribution and Potential Impact on Diabetic Retinopathy Severity
Published in Ophthalmology (Rochester, Minn.) (01-12-2013)“…Objective To assess diabetic retinopathy (DR) as determined by lesions identified using mydriatic ultrawide field imaging (DiSLO200; Optos plc, Scotland, UK)…”
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A Magneto‐optical Molecular Device: Interplay of Spin Crossover, Luminescence, Photomagnetism, and Photochromism
Published in Angewandte Chemie International Edition (04-12-2017)“…A bis(pyrazolylpyridyl) ligand, L, containing a central photochromic dithienylethene spacer predictably forms a ferrous [Fe2L3]4+ helicate exhibiting spin…”
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Randomized Trial Evaluating Ranibizumab Plus Prompt or Deferred Laser or Triamcinolone Plus Prompt Laser for Diabetic Macular Edema
Published in Ophthalmology (Rochester, Minn.) (01-06-2010)“…Objective Evaluate intravitreal 0.5 mg ranibizumab or 4 mg triamcinolone combined with focal/grid laser compared with focal/grid laser alone for treatment of…”
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Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study
Published in Journal of clinical oncology (20-08-2018)“…Purpose The prevalence and features of treatment-emergent small-cell neuroendocrine prostate cancer (t-SCNC) are not well characterized in the era of modern…”
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Collaborative Retrospective Macula Society Study of Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
Published in Ophthalmology (Rochester, Minn.) (01-05-2014)“…Purpose To assess the visual and anatomic outcomes of central serous chorioretinopathy (CSC) after verteporfin photodynamic therapy (PDT). Design Retrospective…”
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Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA
Published in Nature communications (19-10-2020)“…Pancreatic cancer is often detected late, when curative therapies are no longer possible. Here, we present non-invasive detection of pancreatic ductal…”
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Hemorrhage and/or Microaneurysm Severity and Count in Ultrawide Field Images and Early Treatment Diabetic Retinopathy Study Photography
Published in Ophthalmology (Rochester, Minn.) (01-07-2017)“…Objective To evaluate detection of hemorrhage and/or microaneurysm (H/Ma) using ultrawide field (UWF) retinal imaging as compared with standard Early Treatment…”
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Neural Retinal Disorganization as a Robust Marker of Visual Acuity in Current and Resolved Diabetic Macular Edema
Published in Diabetes (New York, N.Y.) (01-07-2015)“…Despite treatment advances, diabetic eye disease remains a leading cause of visual acuity (VA) loss worldwide. No methods to prospectively determine which…”
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Vascular Density of Deep, Intermediate and Superficial Vascular Plexuses Are Differentially Affected by Diabetic Retinopathy Severity
Published in Investigative ophthalmology & visual science (31-08-2020)“…The purpose of this study was to evaluate differences in optical coherence tomography angiography (OCTA) metrics in the superficial (SCP), intermediate (ICP),…”
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Diabetic Retinopathy Severity and Peripheral Lesions Are Associated with Nonperfusion on Ultrawide Field Angiography
Published in Ophthalmology (Rochester, Minn.) (01-12-2015)“…Purpose To assess whether the presence of peripheral nonperfusion on ultrawide field (UWF) fluorescein angiography (FA) is associated with diabetic retinopathy…”
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Angiogenic Pathways in Diabetic Retinopathy
Published in The New England journal of medicine (25-08-2005)“…Visual loss is often considered the most feared complication of human disease, other than death. In 2002, 124 million people worldwide had poor vision and 37…”
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Genomic Drivers of Poor Prognosis and Enzalutamide Resistance in Metastatic Castration-resistant Prostate Cancer
Published in European urology (01-11-2019)“…Metastatic castration-resistant prostate cancer (mCRPC) is the lethal form of the disease. Several recent studies have identified genomic alterations in mCRPC,…”
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Identification of Diabetic Retinopathy and Ungradable Image Rate with Ultrawide Field Imaging in a National Teleophthalmology Program
Published in Ophthalmology (Rochester, Minn.) (01-06-2016)“…Purpose To compare diabetic retinopathy (DR) identification and ungradable image rates between nonmydriatic ultrawide field (UWF) imaging and nonmydriatic…”
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Plasma Kallikrein-Kinin System as a VEGF-Independent Mediator of Diabetic Macular Edema
Published in Diabetes (New York, N.Y.) (01-10-2015)“…This study characterizes the kallikrein-kinin system in vitreous from individuals with diabetic macular edema (DME) and examines mechanisms contributing to…”
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Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer
Published in Cell reports (Cambridge) (06-06-2017)“…Global changes in chromatin accessibility may drive cancer progression by reprogramming transcription factor (TF) binding. In addition, histone acetylation…”
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Rationale for the Diabetic Retinopathy Clinical Research Network Treatment Protocol for Center-Involved Diabetic Macular Edema
Published in Ophthalmology (Rochester, Minn.) (01-12-2011)“…Objective To describe the underlying principles used to develop a web-based algorithm that incorporated intravitreal anti–vascular endothelial growth factor…”
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Anti–Vascular Endothelial Growth Factor Agents in the Treatment of Retinal Disease
Published in Ophthalmology (Rochester, Minn.) (01-10-2016)“…The association of retinal hypoxia with retinal neovascularization has been recognized for decades, causing Michaelson to postulate in 1948 that a factor…”
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Automated Retinal Image Analysis for Diabetic Retinopathy in Telemedicine
Published in Current diabetes reports (01-03-2015)“…There will be an estimated 552 million persons with diabetes globally by the year 2030. Over half of these individuals will develop diabetic retinopathy,…”
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