Search Results - "Lloyd, K."

A metabolome atlas of the aging mouse brain by Ding, Jun, Ji, Jian, Rabow, Zachary, Shen, Tong, Folz, Jacob, Brydges, Christopher R., Fan, Sili, Lu, Xinchen, Mehta, Sajjan, Showalter, Megan R., Zhang, Ying, Araiza, Renee, Bower, Lynette R., Lloyd, K. C. Kent, Fiehn, Oliver

“…The mammalian brain relies on neurochemistry to fulfill its functions. Yet, the complexity of the brain metabolome and its changes during diseases or aging…”
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DNA fragmentation index (DFI) as a measure of sperm quality and fertility in mice by Li, Ming-Wen, Lloyd, K. C. Kent

“…Although thousands of genetically modified mouse strains have been cryopreserved by sperm freezing, the likelihood of cryorecovery success cannot be accurately…”
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Commentary: The International Mouse Phenotyping Consortium: high-throughput in vivo functional annotation of the mammalian genome by Lloyd, K. C. Kent

“…The International Mouse Phenotyping Consortium (IMPC) is a worldwide effort producing and phenotyping knockout mouse lines to expose the pathophysiological…”
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Efficient mouse genome engineering by CRISPR-EZ technology by Modzelewski, Andrew J, Chen, Sean, Willis, Brandon J, Lloyd, K C Kent, Wood, Joshua A, He, Lin

“…CRISPR-EZ achieves 100% delivery of Cas9/sgRNA RNPs by zygote electroporation, enabling efficient incorporation of indels, exon deletions, point mutations, and…”
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Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells by Choi, Yong Jin, Lin, Chao-Po, Risso, Davide, Chen, Sean, Kim, Thomas Aquinas, Tan, Meng How, Li, Jin Billy, Wu, Yalei, Chen, Caifu, Xuan, Zhenyu, Macfarlan, Todd, Peng, Weiqun, Lloyd, K. C. Kent, Kim, Sang Yong, Speed, Terence P., He, Lin

“…Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) efficiently generate all embryonic cell lineages but rarely generate extraembryonic cell…”
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The Mutant Mouse Resource and Research Center (MMRRC): the NIH-supported National Public Repository and Distribution Archive of Mutant Mouse Models in the USA by Amos-Landgraf, James, Franklin, Craig, Godfrey, Virginia, Grieder, Franziska, Grimsrud, Kristin, Korf, Ian, Lutz, Cat, Magnuson, Terry, Mirochnitchenko, Oleg, Patel, Samit, Reinholdt, Laura, Lloyd, K. C. Kent

“…The Mutant Mouse Resource and Research Center (MMRRC) Program is the pre-eminent public national mutant mouse repository and distribution archive in the USA,…”
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A knockout mouse resource for the biomedical research community by Lloyd, K. C. Kent

“…The Knockout Mouse Project (KOMP) Repository archives and distributes vectors, embryonic stem cell clones, frozen germplasm, and live mutant mice for 8,500…”
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Coupling of energy intake and energy expenditure across a temperature spectrum: impact of diet-induced obesity in mice by Ono-Moore, Kikumi D, Rutkowsky, Jennifer M, Pearson, Nicole A, Williams, D Keith, Grobe, Justin L, Tolentino, Todd, Lloyd, K C Kent, Adams, Sean H

“…Obesity and its metabolic sequelae are implicated in dysfunction of the somatosensory, sympathetic, and hypothalamic systems. Because these systems contribute…”
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A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice by Moore, Bret A, Roux, Michel J, Sebbag, Lionel, Cooper, Ann, Edwards, Sydney G, Leonard, Brian C, Imai, Denise M, Griffey, Stephen, Bower, Lynette, Clary, Dave, Lloyd, K C Kent, Hérault, Yann, Thomasy, Sara M, Murphy, Christopher J, Moshiri, Ala

“…The purpose of this study was to quantify the frequency and severity of ocular abnormalities affecting wild-type C57BL/6N mice, the most common strain used…”
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Food additives: Assessing the impact of exposure to permitted emulsifiers on bowel and metabolic health – introducing the FADiets study by Partridge, D., Lloyd, K. A., Rhodes, J. M., Walker, A. W., Johnstone, A. M., Campbell, B. J.

“…Emulsifiers are common components of processed foods consumed as part of a Western diet. Emerging in vitro cell‐line culture, mouse model and human intestinal…”
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High-risk occupations for suicide by Roberts, S E, Jaremin, B, Lloyd, K

“…High occupational suicide rates are often linked to easy occupational access to a method of suicide. This study aimed to compare suicide rates across all…”
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Animal models for studies of HIV‐1 brain reservoirs by Waight, Emiko, Zhang, Chen, Mathews, Saumi, Kevadiya, Bhavesh D., Lloyd, K. C. Kent, Gendelman, Howard E., Gorantla, Santhi, Poluektova, Larisa Y., Dash, Prasanta K.

“…The HIV‐1 often evades a robust antiretroviral‐mediated immune response, leading to persistent infection within anatomically privileged sites including the…”
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Microbial Autotrophy Recorded by Carbonate Dual Clumped Isotope Disequilibrium by Ingalls, Miquela, Leapaldt, Hanna C., Lloyd, Max K.

“…The proliferation of microbial carbon fixation is a key control on the evolution of the biosphere and global carbon cycle. Most records of these metabolisms in…”
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Healthcare contacts with self-harm during COVID-19: An e-cohort whole-population-based study using individual-level linked routine electronic health records in Wales, UK, 2016-March 2021 by DelPozo-Banos, M, Lee, S C, Friedmann, Y, Akbari, A, Torabi, F, Lloyd, K, Lyons, R A, John, A

“…Reduced rates of help seeking by those who self-harmed during the COVID-19 pandemic have been reported. To understand changes in healthcare service contacts…”
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Hypoglycemia after Bariatric Surgery in Mice and Optimal Dosage and Efficacy of Glucose Supplementation by Hsi, Zoe Y, Stewart, Leslie A, Lloyd, KC Kent, Grimsrud, Kristin N

“…The Roux-en-Y Gastric Bypass (RYGB) mouse model is a vital tool for studying the pathophysiology of bariatric surgery and contributes greatly to research on…”
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Borrelia burgdorferi and Borrelia miyamotoi in Atlantic Canadian wildlife by Zinck, Christopher B, Lloyd, Vett K

“…Borrelia burgdorferi and Borrelia miyamotoi are tick-vectored zoonotic pathogens maintained in wildlife species. Tick populations are establishing in new areas…”
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Mixtures of Factor Analyzers with Common Factor Loadings: Applications to the Clustering and Visualization of High-Dimensional Data by Jangsun Baek, McLachlan, Geoffrey J, Flack, Lloyd K

“…Mixtures of factor analyzers enable model-based density estimation to be undertaken for high-dimensional data, where the number of observations n is not very…”
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Gathering of the Clouds: Attending to Indigenous understandings of time and climate through songspirals by Wright, S., Suchet-Pearson, S., Lloyd, K., Burarrwanga, L., Ganambarr, R., Ganambarr-Stubbs, M., Ganambarr, B., Maymuru, D.

“…[Display omitted] •Collaboratively written article with a decolonising approach to climate and weather.•Acknowledges more-than-human agency by recognising…”
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Establishment and range expansion of Dermacentor variabilis in the northern Maritimes of Canada: Community participatory science documents establishment of an invasive tick species by Kirby, Andrea M, Evans, Ellis P, Bishop, Samantha J, Lloyd, Vett K

“…Tick populations are dependent on a complex interplay of abiotic and biotic influences, many of which are influenced by anthropic factors including climate…”
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The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation by Muñoz-Fuentes, Violeta, Cacheiro, Pilar, Meehan, Terrence F., Aguilar-Pimentel, Juan Antonio, Brown, Steve D. M., Flenniken, Ann M., Flicek, Paul, Galli, Antonella, Mashhadi, Hamed Haseli, Hrabě de Angelis, Martin, Kim, Jong Kyoung, Lloyd, K. C. Kent, McKerlie, Colin, Morgan, Hugh, Murray, Stephen A., Nutter, Lauryl M. J., Reilly, Patrick T., Seavitt, John R., Seong, Je Kyung, Simon, Michelle, Wardle-Jones, Hannah, Mallon, Ann-Marie, Smedley, Damian, Parkinson, Helen E.

“…The International Mouse Phenotyping Consortium (IMPC) is building a catalogue of mammalian gene function by producing and phenotyping a knockout mouse line for…”
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