Search Results - "Lloyd, John R."

Enhancement of Thermal Energy Transport Across Graphene/Graphite and Polymer Interfaces: A Molecular Dynamics Study by Luo, Tengfei, Lloyd, John R.

“…Understanding thermal energy transport in polymeric nanocomposite materials is important to the engineering of polymer composites with better engineered heat…”
Get full text

Structural basis of G protein–coupled receptor–G protein interactions by Hu, Jianxin, Wess, Jürgen, Wang, Yan, Zhang, Xiaohong, Lloyd, John R, Li, Jian Hua, Karpiak, Joel, Costanzi, Stefano

“…Crosslinks between the active and inactive M3R and the G-protein G q to which it couples reveal GPCR-G protein movements that can occur upon agonist binding…”
Get full text

Discovery and Synthesis of Namalide Reveals a New Anabaenopeptin Scaffold and Peptidase Inhibitor by Cheruku, Pradeep, Plaza, Alberto, Lauro, Gianluigi, Keffer, Jessica, Lloyd, John R, Bifulco, Giuseppe, Bewley, Carole A

“…The discovery, structure elucidation, and solid-phase synthesis of namalide, a marine natural product, are described. Namalide is a cyclic tetrapeptide; its…”
Get full text

A Corona Discharge Initiated Electrochemical Electrospray Ionization Technique by Lloyd, John R., Hess, Sonja

“…We report here the development of a corona discharge (CD) initiated electrochemical (EC) electrospray ionization (ESI) technique using a standard electrospray…”
Get full text

Non-equilibrium molecular dynamics study of thermal energy transport in Au–SAM–Au junctions by Luo, Tengfei, Lloyd, John R.

“…Non-equilibrium molecular dynamics (NEMD) simulations were performed on Au–SAM (self-assembly monolayer)–Au junctions to study the thermal energy transport…”
Get full text

Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum Complexes by HALL, Matthew D, TELMA, Katherine A, CHANG, Ki-Eun, LEE, Tobie D, MADIGAN, James P, LLOYD, John R, GOLDLUST, Ian S, HOESCHELE, James D, GOTTESMAN, Michael M

“…The platinum drugs cisplatin, carboplatin, and oxaliplatin are highly utilized in the clinic and as a consequence are extensively studied in the laboratory…”
Get full text

Geographic variability and anti-staphylococcal activity of the chrysophaentins and their synthetic fragments by Keffer, Jessica L, Hammill, Jared T, Lloyd, John R, Plaza, Alberto, Wipf, Peter, Bewley, Carole A

“…Drug-resistant Staphylococcus aureus is a continuing public health concern, both in the hospital and community settings. Antibacterial compounds that possess…”
Get full text

Meropenem inhibits D,D-carboxypeptidase activity in Mycobacterium tuberculosis by Kumar, Pradeep, Arora, Kriti, Lloyd, John R., Lee, Ill Y., Nair, Vinod, Fischer, Elizabeth, Boshoff, Helena I. M., Barry III, Clifton E.

“…Summary Carbapenems such as meropenem are being investigated for their potential therapeutic utility against highly drug‐resistant tuberculosis. These…”
Get full text

Chrysophaentins A−H, Antibacterial Bisdiarylbutene Macrocycles That Inhibit the Bacterial Cell Division Protein FtsZ by Plaza, Alberto, Keffer, Jessica L, Bifulco, Giuseppe, Lloyd, John R, Bewley, Carole A

“…Eight new antimicrobial natural products named chrysophaentins A−H belonging to a new structural class have been isolated from the marine chrysophyte alga…”
Get full text

Chlorcyclizine Inhibits Viral Fusion of Hepatitis C Virus Entry by Directly Targeting HCV Envelope Glycoprotein 1 by Hu, Zongyi, Rolt, Adam, Hu, Xin, Ma, Christopher D, Le, Derek J, Park, Seung Bum, Houghton, Michael, Southall, Noel, Anderson, D Eric, Talley, Daniel C, Lloyd, John R, Marugan, Juan C, Liang, T Jake

“…Chlorcyclizine (CCZ) is a potent hepatitis C virus (HCV) entry inhibitor, but its molecular mechanism is unknown. Here, we show that CCZ directly targets the…”
Get more information

Celebesides A−C and Theopapuamides B−D, Depsipeptides from an Indonesian Sponge That Inhibit HIV-1 Entry by Plaza, Alberto, Bifulco, Giuseppe, Keffer, Jessica L, Lloyd, John R, Baker, Heather L, Bewley, Carole A

“…Six new depsipeptides belonging to two different structural classes, termed celebesides A−C and theopapuamides B−D, have been isolated from the marine sponge…”
Get full text

Peptide Fragmentation by Corona Discharge Induced Electrochemical Ionization by Lloyd, John R., Hess, Sonja

“…Fundamental studies have greatly improved our understanding of electrospray, including the underlying electrochemical reactions. Generally regarded as…”
Get full text

Mutremdamide A and Koshikamides C−H, Peptide Inhibitors of HIV-1 Entry from Different Theonella Species by Plaza, Alberto, Bifulco, Giuseppe, Masullo, Milena, Lloyd, John R, Keffer, Jessica L, Colin, Patrick L, Hooper, John N. A, Bell, Lori J, Bewley, Carole A

“…A new sulfated cyclic depsipeptide, termed mutremdamide A, and six new highly N-methylated peptides, termed koshikamides C−H, were isolated from different…”
Get full text

Evaluation of fluorophore-tethered platinum complexes to monitor the fate of cisplatin analogs by Jagodinsky, Justin C., Sulima, Agnieszka, Cao, Yiqi, Poprawski, Joanna E., Blackman, Burchelle N., Lloyd, John R., Swenson, Rolf E., Gottesman, Michael M., Hall, Matthew D.

“…The platinum drugs cisplatin, carboplatin, and oxaliplatin are highly utilized in the clinic and as a consequence have been extensively studied in the…”
Get full text

Treatment Adherence Associated With Conventional and Atypical Antipsychotics in a Large State Medicaid Program by Menzin, Joseph, Boulanger, Luke, Friedman, Mark, Mackell, Joan, Lloyd, John R

“…OBJECTIVES: Rates of medication adherence over a one-year period were assessed among outpatients with schizophrenia who initiated therapy with conventional or…”
Get full text

Paltolides A−C, Anabaenopeptin-Type Peptides from the Palau Sponge Theonella swinhoei by Plaza, Alberto, Keffer, Jessica L, Lloyd, John R, Colin, Patrick L, Bewley, Carole A

“…Three new anabaenopeptin-like peptides, named paltolides A−C, were isolated from a deep-water specimen of the marine sponge Theonella swinhoei from Palau…”
Get full text

Assessment of 4-Nitrogenated Benzyloxymethyl Groups for 2‘-Hydroxyl Protection in Solid-Phase RNA Synthesis by Cieślak, Jacek, Kauffman, Jon S, Kolodziejski, Michelle J, Lloyd, John R, Beaucage, Serge L

“…The search for a 2‘-OH protecting group that would impart ribonucleoside phosphoramidites with coupling kinetics and coupling efficiencies comparable to those…”
Get full text

Solid-Phase Synthesis of Thermolytic DNA Oligonucleotides Functionalized with a Single 4-Hydroxy-1-butyl or 4-Phosphato-/Thiophosphato-1-butyl Thiophosphate Protecting Group by Grajkowski, Andrzej, Ausín, Cristina, Kauffman, Jon S, Snyder, John, Hess, Sonja, Lloyd, John R, Beaucage, Serge L

“…Several thermolytic CpG-containing DNA oligonucleotides analogous to 1 have been synthesized to serve as potential immunotherapeutic oligonucleotide prodrug…”
Get full text

Structural Assignment of Poecillastrins B and C, Macrolide Lactams from the Deep-Water Caribbean Sponge Poecillastra Species by Takada, Kentaro, Choi, Byoung W, Rashid, Mohammad A, Gamble, William R, Cardellina, John H, Van, Que N, Lloyd, John R, McMahon, James B, Gustafson, Kirk R

“…Two new chondropsin-type macrolide lactams, poecillastrins B (1) and C (2), were isolated from aqueous extracts of the marine sponge Poecillastra sp. These…”
Get full text

Iron- and 4-hydroxy-2-alkylquinoline-containing periplasmic inclusion bodies of Pseudomonas aeruginosa: A chemical analysis by Royt, Paulette W., Honeychuck, Robert V., Pant, Ramesh R., Rogers, Magnus L., Asher, Ludmila V., Lloyd, John R., Carlos, W.E., Belkin, Harvey E., Patwardhan, Swati

“…Iron-rich Pseudomonas aeruginosa forms periplasmic inclusion bodies that contain iron and five different 4-hydroxy-2-alkylquinolines including the Pseudomonas…”
Get full text